Pharmacological activation of TRPV4 produces immediate cell damage and induction of apoptosis in human melanoma cells and HaCaT keratinocytes

TRPV4 Mediates Mast Cell Activation in Cathelicidin-Induced Rosacea Inflammation

(2017) Nicholas L. Mascarenhas et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

TRPV4 Moves toward Center-Fold in Rosacea Pathogenesis

(2017) Yong Chen et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Emerging roles of calcium-activated K channels and TRPV4 channels in lung oedema and pulmonary circulatory collapse

(2016) U. Simonsen et al.   Acta Physiologica

Baicalein increases keratin 1 and 10 expression in HaCaT keratinocytes via TRPV4 receptor activation

(2016) Kuo-Feng Huang et al.   EXPERIMENTAL DERMATOLOGY

KCa3.1 (IK) modulates pancreatic cancer cell migration, invasion and proliferation: anomalous effects on TRAM-34

(2016) B. Bonito et al.   PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY

TRPV4: Molecular Conductor of a Diverse Orchestra

(2016) John P. M. White et al.   PHYSIOLOGICAL REVIEWS

Inhibition of SK4 Potassium Channels Suppresses Cell Proliferation, Migration and the Epithelial-Mesenchymal Transition in Triple-Negative Breast Cancer Cells

(2016) Panshi Zhang et al.   PLoS One

Melanin content in melanoma metastases affects the outcome of radiotherapy

(2016) Anna A. Brożyna et al.   Oncotarget

TRPV4 channels regulate tumor angiogenesis via modulation of Rho/Rho kinase pathway

(2016) Roslin J. Thoppil et al.   Oncotarget

TRPV4 Regulates Breast Cancer Cell Extravasation, Stiffness and Actin Cortex

(2016) Wen Hsin Lee et al.   Scientific Reports

Pharmacological inhibitors of TRPV4 channels reduce cytokine production, restore endothelial function and increase survival in septic mice

(2016) Thomas Dalsgaard et al.   Scientific Reports

High Expression of KCa3.1 in Patients with Clear Cell Renal Carcinoma Predicts High Metastatic Risk and Poor Survival

(2015) Maj Rabjerg et al.   PLoS One

The role of melanogenesis in regulation of melanoma behavior: Melanogenesis leads to stimulation of HIF-1α expression and HIF-dependent attendant pathways

(2014) A. Slominski et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

Targeting proliferation of chronic lymphocytic leukemia (CLL) cells through KCa3.1 blockade

(2014) E M Grössinger et al.   LEUKEMIA

Pivotal Role of the Lipid Raft SK3-Orai1 Complex in Human Cancer Cell Migration and Bone Metastases

(2013) A. Chantome et al.   CANCER RESEARCH

The puzzle of TRPV4 channelopathies

(2013) Bernd Nilius et al.   EMBO REPORTS

Novel Phenolic Inhibitors of Small/Intermediate-Conductance Ca2+-Activated K+ Channels, KCa3.1 and KCa2.3

(2013) Aida Oliván-Viguera et al.   PLoS One

UVB radiation generates sunburn pain and affects skin by activating epidermal TRPV4 ion channels and triggering endothelin-1 signaling

(2013) Carlene Moore et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

KCa3.1 channels are involved in the infiltrative behavior of glioblastoma in vivo

(2013) G D'Alessandro et al.   Cell Death & Disease

An Orally Active TRPV4 Channel Blocker Prevents and Resolves Pulmonary Edema Induced by Heart Failure

(2012) Kevin S. Thorneloe et al.   Science Translational Medicine

Migration-associated secretion of melanoma inhibitory activity at the cell rear is supported by KCa3.1 potassium channels

(2010) Jennifer Schmidt et al.   CELL RESEARCH

Inhibition of the cation channel TRPV4 improves bladder function in mice and rats with cyclophosphamide-induced cystitis

(2010) W. Everaerts et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Inhibition of melanogenesis as a radiation sensitizer for melanoma therapy

(2008) Anna A. Brożyna et al.   INTERNATIONAL JOURNAL OF CANCER

Systemic Activation of the Transient Receptor Potential Vanilloid Subtype 4 Channel Causes Endothelial Failure and Circulatory Collapse: Part 2

(2008) R. N. Willette et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS