Novel Phenolic Inhibitors of Small/Intermediate-Conductance Ca2+-Activated K+ Channels, KCa3.1 and KCa2.3

Activation of endothelial and epithelial KCa2.3 calcium-activated potassium channels by NS309 relaxes human small pulmonary arteries and bronchioles

(2012) Christel Kroigaard et al.   BRITISH JOURNAL OF PHARMACOLOGY

Modafinil inhibits KCa3.1 currents and muscle contraction via a cAMP-dependent mechanism

(2012) Shinkyu Choi et al.   PHARMACOLOGICAL RESEARCH

Genetic KCa3.1-Deficiency Produces Locomotor Hyperactivity and Alterations in Cerebral Monoamine Levels

(2012) Kate Lykke Lambertsen et al.   PLoS One

Identification of the functional binding pocket for compounds targeting small-conductance Ca2+-activated potassium channels

(2012) Miao Zhang et al.   Nature Communications

Trivanillic polyphenols with anticancer cytostatic effects through the targeting of multiple kinases and intracellular Ca2+release

(2011) Delphine Lamoral-Theys et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Functional ion channels and cell proliferation in 3T3-L1 preadipocytes

(2011) Xiao-Hua Zhang et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Protein kinase A signalling is involved in the relaxant responses to the selectiveβ-oestrogen receptor agonist diarylpropionitrile in rat aortic smooth musclein vitro

(2011) Marta S. Valero et al.   JOURNAL OF PHARMACY AND PHARMACOLOGY

Pirfenidone in patients with idiopathic pulmonary fibrosis (CAPACITY): two randomised trials

(2011) Paul W Noble et al.   LANCET

Negative Gating Modulation by (R)-N-(Benzimidazol-2-yl)-1,2,3,4-tetrahydro-1-naphthylamine (NS8593) Depends on Residues in the Inner Pore Vestibule: Pharmacological Evidence of Deep-Pore Gating of KCa2 Channels

(2011) D. P. Jenkins et al.   MOLECULAR PHARMACOLOGY

Simple di- and trivanillates exhibit cytostatic properties toward cancer cells resistant to pro-apoptotic stimuli

(2010) Delphine Lamoral-Theys et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Vascular KCa-channels as therapeutic targets in hypertension and restenosis disease

(2010) Ralf Köhler et al.   EXPERT OPINION ON THERAPEUTIC TARGETS

Endothelium-independent vasorelaxation by the selective alpha estrogen receptor agonist propyl pyrazole triol in rat aortic smooth muscle

(2010) José O. Alda et al.   JOURNAL OF PHARMACY AND PHARMACOLOGY

Calcium-Activated Potassium Channels BK and IK1 Are Functionally Expressed in Human Gliomas but Do Not Regulate Cell Proliferation

(2010) Iskandar F. Abdullaev et al.   PLoS One

Genetic Deficit of SK3 and IK1 Channels Disrupts the Endothelium-Derived Hyperpolarizing Factor Vasodilator Pathway and Causes Hypertension

(2009) Sebastian Brähler et al.   CIRCULATION

The Class II Phosphatidylinositol 3 kinase C2β Is Required for the Activation of the K+ Channel KCa3.1 and CD4 T-Cells

(2009) Shekhar Srivastava et al.   MOLECULAR BIOLOGY OF THE CELL

Renal fibrosis is attenuated by targeted disruption of KCa3.1 potassium channels

(2009) I. Grgic et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Local Delivery of the K Ca 3.1 Blocker, TRAM-34, Prevents Acute Angioplasty-Induced Coronary Smooth Muscle Phenotypic Modulation and Limits Stenosis

(2008) D.L. Tharp et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

K+Channel Modulators for the Treatment of Neurological Disorders and Autoimmune Diseases

(2008) Heike Wulff et al.   CHEMICAL REVIEWS

Targeting Ion Channels in Cancer: A Novel Frontier in Antineoplastic Therapy

(2008) A. Arcangeli et al.   CURRENT MEDICINAL CHEMISTRY

The intermediate-conductance calcium-activated potassium channel KCa3.1 contributes to atherogenesis in mice and humans

(2008) Kazuyoshi Toyama et al.   JOURNAL OF CLINICAL INVESTIGATION

Ca2+-activated K+Channels in Murine Endothelial Cells: Block by Intracellular Calcium and Magnesium

(2008) Jonathan Ledoux et al.   JOURNAL OF GENERAL PHYSIOLOGY

Naphtho[1,2-d]thiazol-2-ylamine (SKA-31), a New Activator of KCa2 and KCa3.1 Potassium Channels, Potentiates the Endothelium-Derived Hyperpolarizing Factor Response and Lowers Blood Pressure

(2008) A. Sankaranarayanan et al.   MOLECULAR PHARMACOLOGY

Disruption of the Gardos channel (KCa3.1) in mice causes subtle erythrocyte macrocytosis and progressive splenomegaly

(2008) Ivica Grgic et al.   PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY

Protein histidine phosphatase 1 negatively regulates CD4 T cells by inhibiting the K+ channel KCa3.1

(2008) S. Srivastava et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA