Catalpol provides a protective effect on fibrillary Aβ1-42 -induced barrier disruption in an in vitro model of the blood-brain barrier

The potential mechanism for Hydroxysafflor yellow A attenuating blood-brain barrier dysfunction via tight junction signaling pathways excavated by an integrated serial affinity chromatography and shotgun proteomics analysis approach

(2018) Yanni Lv et al.   NEUROCHEMISTRY INTERNATIONAL

Catalpol restores LPS-elicited rat microcirculation disorder by regulation of a network of signaling involving inhibition of TLR-4 and SRC

(2016) Yun-Pei Zhang et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

High-Throughput Screening for Identification of Blood-Brain Barrier Integrity Enhancers: A Drug Repurposing Opportunity to Rectify Vascular Amyloid Toxicity

(2016) Hisham Qosa et al.   JOURNAL OF ALZHEIMERS DISEASE

Catalpol stimulates VEGF production via the JAK2/STAT3 pathway to improve angiogenesis in rats’ stroke model

(2016) Wan Dong et al.   JOURNAL OF ETHNOPHARMACOLOGY

1,25-Dihydroxyvitamin D3 regulates expression of LRP1 and RAGE in vitro and in vivo, enhancing Aβ1–40 brain-to-blood efflux and peripheral uptake transport

(2016) Y.-X. Guo et al.   NEUROSCIENCE

Amyloid β oligomers elicit mitochondrial transport defects and fragmentation in a time-dependent and pathway-specific manner

(2016) Yanfang Rui et al.   Molecular Brain

Aβ induces PUMA activation: a new mechanism for Aβ-mediated neuronal apoptosis

(2015) Jie Feng et al.   NEUROBIOLOGY OF AGING

The Molecular Constituents of the Blood–Brain Barrier

(2015) Brian Wai Chow et al.   TRENDS IN NEUROSCIENCES

Oxidative and pro-inflammatory impact of regular and denicotinized cigarettes on blood brain barrier endothelial cells: is smoking reduced or nicotine-free products really safe?

(2014) Pooja Naik et al.   BMC NEUROSCIENCE

Oligomeric Aβ-induced synaptic dysfunction in Alzheimer’s disease

(2014) Shichun Tu et al.   Molecular Neurodegeneration

Blood–Brain Barrier Dysfunction as a Cause and Consequence of Alzheimer's Disease

(2013) Michelle A Erickson et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

A 1-42-RAGE Interaction Disrupts Tight Junctions of the Blood-Brain Barrier Via Ca2+-Calcineurin Signaling

(2012) S.-Y. Kook et al.   JOURNAL OF NEUROSCIENCE

Ischemia–reperfusion impairs blood–brain barrier function and alters tight junction protein expression in the ovine fetus

(2012) X. Chen et al.   NEUROSCIENCE

Low-density lipoprotein receptor-related protein 1: A physiological Aβ homeostatic mechanism with multiple therapeutic opportunities

(2012) Abhay P. Sagare et al.   PHARMACOLOGY & THERAPEUTICS

The Interaction of Amyloid β and the Receptor for Advanced Glycation Endproducts Induces Matrix Metalloproteinase-2 Expression in Brain Endothelial Cells

(2011) Huan Du et al.   CELLULAR AND MOLECULAR NEUROBIOLOGY

Insights into Caspase-Mediated Apoptotic Pathways Induced by Amyloid-ß in Cerebral Microvascular Endothelial Cells

(2011) Silvia Fossati et al.   Neurodegenerative Diseases

Amyloid-β Contributes to Blood–Brain Barrier Leakage in Transgenic Human Amyloid Precursor Protein Mice and in Humans With Cerebral Amyloid Angiopathy

(2011) Anika M.S. Hartz et al.   STROKE

MDR1–P-glycoprotein (ABCB1)-Mediated Disposition of Amyloid-β Peptides: Implications for the Pathogenesis and Therapy of Alzheimer’s Disease

(2010) G Jedlitschky et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

Blood-Brain-Barrier Models for the Investigation of Transporter- and Receptor-Mediated Amyloid-β Clearance in Alzheimers Disease

(2010) T. Pflanzner et al.   Current Alzheimer Research

Amyloid β-peptide 31-35-induced neuronal apoptosis is mediated by caspase-dependent pathways via cAMP-dependent protein kinase A activation

(2009) Li Zhao et al.   AGING CELL

Clearance of Amyloid-β Peptide Across the Blood-Brain Barrier: Implication for Therapies in Alzheimers Disease

(2009) R. Deane et al.   CNS & Neurological Disorders-Drug Targets

Catalpol protects primary cultured cortical neurons induced by Aβ1–42 through a mitochondrial-dependent caspase pathway

(2009) Jian Hua Liang et al.   NEUROCHEMISTRY INTERNATIONAL

Tight junctions and the modulation of barrier function in disease

(2008) Carola Förster   HISTOCHEMISTRY AND CELL BIOLOGY

Soluble aggregates of the amyloid-β protein selectively stimulate permeability in human brain microvascular endothelial monolayers

(2008) Francisco J. Gonzalez-Velasquez et al.   JOURNAL OF NEUROCHEMISTRY

Catalpol attenuates the neurotoxicity induced by β-amyloid1–42 in cortical neuron–glia cultures

(2007) Bo Jiang et al.   BRAIN RESEARCH