Genome-wide association study of response to methotrexate in early rheumatoid arthritis patients

GeneImp: Fast Imputation to Large Reference Panels Using Genotype Likelihoods from Ultralow Coverage Sequencing

(2017) Athina Spiliopoulou et al.   GENETICS

The autoimmune risk gene ZMIZ1 is a vitamin D responsive marker of a molecular phenotype of multiple sclerosis

(2017) N.L. Fewings et al.   JOURNAL OF AUTOIMMUNITY

GeneImp: Fast Imputation to Large Reference Panels Using Genotype Likelihoods from Ultralow Coverage Sequencing

(2017) Athina Spiliopoulou et al.   GENETICS

Paracetamol: a probably still safe drug

(2016) Alessandro Battaggia et al.   ANNALS OF THE RHEUMATIC DISEASES

A prospective, single-centre, randomised study evaluating the clinical, imaging and immunological depth of remission achieved by very early versus delayed Etanercept in patients with Rheumatoid Arthritis (VEDERA)

(2016) Raluca B. Dumitru et al.   BMC MUSCULOSKELETAL DISORDERS

Stratified medicine in rheumatoid arthritis—the MATURA programme

(2016) Anne Barton et al.   RHEUMATOLOGY

Brief Report: Predicting Functional Disability: One-Year Results From the Scottish Early Rheumatoid Arthritis Inception Cohort

(2016) Caroline Kronisch et al.   Arthritis & Rheumatology

Evidence for treating rheumatoid arthritis to target: results of a systematic literature search update

(2015) Michaela A Stoffer et al.   ANNALS OF THE RHEUMATIC DISEASES

Role of RSUME in inflammation and cancer

(2015) Valeria G. Antico Arciuch et al.   FEBS LETTERS

A randomised controlled trial of etanercept and methotrexate to induce remission in early inflammatory arthritis: the EMPIRE trial

(2014) J L Nam et al.   ANNALS OF THE RHEUMATIC DISEASES

Estimation of heritability of different outcomes for genetic studies of TNFi response in patients with rheumatoid arthritis

(2014) Maša Umićević Mirkov et al.   ANNALS OF THE RHEUMATIC DISEASES

Genetic and epigenetic predictors of responsiveness to treatment in RA

(2014) Darren Plant et al.   Nature Reviews Rheumatology

Genome-wide analysis of methotrexate pharmacogenomics in rheumatoid arthritis shows multiple novel risk variants and leads for TYMS regulation

(2014) Sabyasachi Senapati et al.   Pharmacogenetics and Genomics

Genome-wide data reveal novel genes for methotrexate response in a large cohort of juvenile idiopathic arthritis cases

(2014) J Cobb et al.   PHARMACOGENOMICS JOURNAL

Safety with Ocrelizumab in Rheumatoid Arthritis: Results from the Ocrelizumab Phase III Program

(2014) Paul Emery et al.   PLoS One

Haplotype Estimation Using Sequencing Reads

(2013) Olivier Delaneau et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Remission induction comparing infliximab and high-dose intravenous steroid, followed by treat-to-target: a double-blind, randomised, controlled trial in new-onset, treatment-naive, rheumatoid arthritis (the IDEA study)

(2013) J L Nam et al.   ANNALS OF THE RHEUMATIC DISEASES

Genetics of rheumatoid arthritis contributes to biology and drug discovery

(2013) Yukinori Okada et al.   NATURE

Analysis of immune-related loci identifies 48 new susceptibility variants for multiple sclerosis

(2013) Ashley H Beecham et al.   NATURE GENETICS

RFC180G>A Is a Genetic Determinant of Methotrexate Efficacy in Rheumatoid Arthritis: A Human Genome Epidemiologic Review and Meta-Analysis of Observational Studies

(2013) Tabitha N. Kung et al.   Arthritis & Rheumatology

Combined Analysis of Genome-wide Association Studies for Crohn Disease and Psoriasis Identifies Seven Shared Susceptibility Loci

(2012) David Ellinghaus et al.   AMERICAN JOURNAL OF HUMAN GENETICS

A randomized comparative effectiveness study of oral triple therapy versus etanercept plus methotrexate in early aggressive rheumatoid arthritis: The Treatment of Early Aggressive Rheumatoid Arthritis trial

(2012) Larry W. Moreland et al.   ARTHRITIS AND RHEUMATISM

Association of the TYMS 3G/3G genotype with poor response and GGH 354GG genotype with the bone marrow toxicity of the methotrexate in RA patients

(2012) Biljana Jekic et al.   EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY

The clinical picture of rheumatoid arthritis according to the 2010 American College of Rheumatology/European League Against Rheumatism criteria: Is this still the same disease?

(2011) M. J. H. de Hair et al.   ARTHRITIS AND RHEUMATISM

PharmGKB summary

(2011) Torben S. Mikkelsen et al.   Pharmacogenetics and Genomics

Efficacy and safety of different doses and retreatment of rituximab: a randomised, placebo-controlled trial in patients who are biological naive with active rheumatoid arthritis and an inadequate response to methotrexate (Study Evaluating Rituximab's Efficacy in MTX iNadequate rEsponders (SERENE))

(2010) P. Emery et al.   ANNALS OF THE RHEUMATIC DISEASES

Evidence for treating rheumatoid arthritis to target: results of a systematic literature search

(2010) M. Schoels et al.   ANNALS OF THE RHEUMATIC DISEASES

Treating rheumatoid arthritis to target: recommendations of an international task force

(2010) J. S. Smolen et al.   ANNALS OF THE RHEUMATIC DISEASES

Inhibition of joint damage and improved clinical outcomes with rituximab plus methotrexate in early active rheumatoid arthritis: the IMAGE trial

(2010) P. P. Tak et al.   ANNALS OF THE RHEUMATIC DISEASES

Gene profiling predicts rheumatoid arthritis responsiveness to IL-1Ra (anakinra)

(2010) C. Bansard et al.   RHEUMATOLOGY

Persistently moderate DAS-28 is not benign: loss of function occurs in early RA despite step-up DMARD therapy

(2010) P. G. Conaghan et al.   RHEUMATOLOGY

Efficacy and safety of various repeat treatment dosing regimens of rituximab in patients with active rheumatoid arthritis: results of a Phase III randomized study (MIRROR)

(2010) A. Rubbert-Roth et al.   RHEUMATOLOGY

Comparison of tocilizumab monotherapy versus methotrexate monotherapy in patients with moderate to severe rheumatoid arthritis: the AMBITION study

(2009) G. Jones et al.   ANNALS OF THE RHEUMATIC DISEASES

EGFR ligands and their signaling scissors, ADAMs, as new molecular targets for anticancer treatments

(2009) Hiromi Kataoka   JOURNAL OF DERMATOLOGICAL SCIENCE

Addition of infliximab compared with addition of sulfasalazine and hydroxychloroquine to methotrexate in patients with early rheumatoid arthritis (Swefot trial): 1-year results of a randomised trial

(2009) RF van Vollenhoven et al.   LANCET

Treatment of rheumatoid arthritis: state of the art 2009

(2009) Ronald F. van Vollenhoven   Nature Reviews Rheumatology

Investigation of candidate polymorphisms and disease activity in rheumatoid arthritis patients on methotrexate

(2009) Y. C. Lee et al.   RHEUMATOLOGY

A Flexible and Accurate Genotype Imputation Method for the Next Generation of Genome-Wide Association Studies

(2009) Bryan N. Howie et al.   PLoS Genetics

Genome-wide association study of rheumatoid arthritis in the Spanish population:KLF12as a risk locus for rheumatoid arthritis susceptibility

(2008) Antonio Julià et al.   ARTHRITIS AND RHEUMATISM

Principal component analysis of genetic data

(2008) David Reich et al.   NATURE GENETICS