RFC180G>A Is a Genetic Determinant of Methotrexate Efficacy in Rheumatoid Arthritis: A Human Genome Epidemiologic Review and Meta-Analysis of Observational Studies

A Single Nucleotide Polymorphism of Reduced Folate Carrier 1 Predicts Methotrexate Efficacy in Japanese Patients with Rheumatoid Arthritis

(2013) Hideki Hayashi et al.   Drug Metabolism and Pharmacokinetics

Polymorphisms in Methotrexate Pathways: What Is Clinically Relevant, What Is Not, and What Is Promising

(2012) Guillermo Gervasini   CURRENT DRUG METABOLISM

Genetic polymorphisms in key methotrexate pathway genes are associated with response to treatment in rheumatoid arthritis patients

(2012) S A Owen et al.   PHARMACOGENOMICS JOURNAL

The role of MTHFR and RFC1 polymorphisms on toxicity and outcome of adult patients with hematological malignancies treated with high-dose methotrexate followed by leucovorin rescue

(2011) Patrizia Chiusolo et al.   CANCER CHEMOTHERAPY AND PHARMACOLOGY

Developing a Construct to Evaluate Flares in Rheumatoid Arthritis: A Conceptual Report of the OMERACT RA Flare Definition Working Group

(2011) R. ALTEN et al.   JOURNAL OF RHEUMATOLOGY

Canadian Rheumatology Association Recommendations for Pharmacological Management of Rheumatoid Arthritis with Traditional and Biologic Disease-modifying Antirheumatic Drugs

(2011) VIVIAN P. BYKERK et al.   JOURNAL OF RHEUMATOLOGY

MTHFR gene polymorphisms and outcome of methotrexate treatment in patients with rheumatoid arthritis: analysis of key polymorphisms and meta-analysis of C677T and A1298C polymorphisms

(2011) S A Owen et al.   PHARMACOGENOMICS JOURNAL

The C677T polymorphism in theMTHFRgene is associated with the toxicity of methotrexate in a Spanish rheumatoid arthritis population

(2011) R Cáliz et al.   SCANDINAVIAN JOURNAL OF RHEUMATOLOGY

Long-term impact of delay in assessment of patients with early arthritis

(2010) Michael P. M. van der Linden et al.   ARTHRITIS AND RHEUMATISM

The association of reduced folate carrier 80G>A polymorphism to outcome in childhood acute lymphoblastic leukemia interacts with chromosome 21 copy number

(2010) J. Gregers et al.   BLOOD

Associations between the C677T and A1298C Polymorphisms of MTHFR and the Efficacy and Toxicity of Methotrexate in Rheumatoid Arthritis

(2010) Young Ho Lee et al.   CLINICAL DRUG INVESTIGATION

Care Gap in Patients with Early Inflammatory Arthritis with a High Fracture Risk Identified Using FRAX(R)

(2010) C. K. CHENG et al.   JOURNAL OF RHEUMATOLOGY

Polymorphisms within the folate pathway predict folate concentrations but are not associated with disease activity in rheumatoid arthritis patients on methotrexate

(2010) Lisa K. Stamp et al.   Pharmacogenetics and Genomics

Metaanalysis of Methylenetetrahydrofolate Reductase (MTHFR) Polymorphisms Affecting Methotrexate Toxicity

(2009) M. C. FISHER et al.   JOURNAL OF RHEUMATOLOGY

Reduced folate carrier and methylenetetrahydrofolate reductase gene polymorphisms: associations with clinical outcome in childhood acute lymphoblastic leukemia

(2009) L J Ashton et al.   LEUKEMIA

Gene–gene interactions in folate and adenosine biosynthesis pathways affect methotrexate efficacy and tolerability in rheumatoid arthritis

(2009) Thierry Dervieux et al.   Pharmacogenetics and Genomics

Radiographic changes in rheumatoid arthritis patients attaining different disease activity states with methotrexate monotherapy and infliximab plus methotrexate: the impacts of remission and tumour necrosis factor blockade

(2008) J S Smolen et al.   ANNALS OF THE RHEUMATIC DISEASES

Long-term safety of methotrexate monotherapy in patients with rheumatoid arthritis: a systematic literature research

(2008) C Salliot et al.   ANNALS OF THE RHEUMATIC DISEASES

Genetic determinants of methotrexate toxicity in rheumatoid arthritis patients: a study of polymorphisms affecting methotrexate transport and folate metabolism

(2008) Petra Bohanec Grabar et al.   EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY