Fampridine is a Substrate and Inhibitor of Human OCT2, but not of Human MATE1, or MATE2K

Emtricitabine is a substrate of MATE1 but not of OCT1, OCT2, P-gp, BCRP or MRP2 transporters

(2016) Josef Reznicek et al.   XENOBIOTICA

The Effect of Famotidine, a MATE1-Selective Inhibitor, on the Pharmacokinetics and Pharmacodynamics of Metformin

(2015) Jennifer E. Hibma et al.   CLINICAL PHARMACOKINETICS

The Effect of Nizatidine, a MATE2K Selective Inhibitor, on the Pharmacokinetics and Pharmacodynamics of Metformin in Healthy Volunteers

(2015) Kari M. Morrissey et al.   CLINICAL PHARMACOKINETICS

Involvement of Organic Cation Transporters in the Clearance and Milk Secretion of Thiamine in Mice

(2015) Koji Kato et al.   PHARMACEUTICAL RESEARCH

Substrate-Dependent Inhibition of the Human Organic Cation Transporter OCT2: A Comparison of Metformin with Experimental Substrates

(2015) Kristina Hacker et al.   PLoS One

Organic Cation Transporter OCTs (SLC22) and MATEs (SLC47) in the Human Kidney

(2013) Hideyuki Motohashi et al.   AAPS Journal

Precise comparison of protein localization among OCT, OAT, and MATE in human kidney

(2013) Hideyuki Motohashi et al.   JOURNAL OF PHARMACEUTICAL SCIENCES

Ondansetron can enhance cisplatin-induced nephrotoxicity via inhibition of multiple toxin and extrusion proteins (MATEs)

(2013) Qing Li et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Discovery of Potent, Selective Multidrug and Toxin Extrusion Transporter 1 (MATE1, SLC47A1) Inhibitors Through Prescription Drug Profiling and Computational Modeling

(2012) Matthias B. Wittwer et al.   JOURNAL OF MEDICINAL CHEMISTRY

Characterization of the human MATE2 proton-coupled polyspecific organic cation exporter

(2011) Toshinori Komatsu et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Profiling of a Prescription Drug Library for Potential Renal Drug–Drug Interactions Mediated by the Organic Cation Transporter 2

(2011) Yasuto Kido et al.   JOURNAL OF MEDICINAL CHEMISTRY

Interactions of Tyrosine Kinase Inhibitors with Organic Cation Transporters and Multidrug and Toxic Compound Extrusion Proteins

(2011) T. Minematsu et al.   MOLECULAR CANCER THERAPEUTICS

Potent and Specific Inhibition of mMate1-Mediated Efflux of Type I Organic Cations in the Liver and Kidney by Pyrimethamine

(2010) S. Ito et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS