Implication of the PI3K/Akt/mTOR Pathway in the Process of Incompetent Valves in Patients with Chronic Venous Insufficiency and the Relationship with Aging

Bone marrow mesenchymal stem cells conditioned medium protects VSC4.1 cells against 2,5-hexanedione-induced autophagy via NGF-PI3K/Akt/mTOR signaling pathway

(2018) Xin Zhang et al.   BRAIN RESEARCH

Placentas from women with pregnancy-associated venous insufficiency show villi damage with evidence of hypoxic cellular stress

(2018) Natalio García-Honduvilla et al.   HUMAN PATHOLOGY

Human venous valve disease caused by mutations inFOXC2andGJC2

(2017) Oliver Lyons et al.   JOURNAL OF EXPERIMENTAL MEDICINE

SRC-3 Plays a Critical Role in Human Umbilical Vein Endothelial Cells by Regulating the PI3K/Akt/mTOR Pathway in Preeclampsia

(2017) Yu Yuan et al.   Reproductive Sciences

Rapamycin Prevents cyclophosphamide-induced Over-activation of Primordial Follicle pool through PI3K/Akt/mTOR Signaling Pathway in vivo

(2017) Linyan Zhou et al.   Journal of Ovarian Research

A neuropeptide, Substance-P, directly induces tissue-repairing M2 like macrophages by activating the PI3K/Akt/mTOR pathway even in the presence of IFNγ

(2017) Ji Eun Lim et al.   Scientific Reports

Somatic overgrowth disorders of the PI3K/AKT/mTOR pathway & therapeutic strategies

(2016) Kim M. Keppler-Noreuil et al.   AMERICAN JOURNAL OF MEDICAL GENETICS PART C-SEMINARS IN MEDICAL GENETICS

Interleukin-1β Plays a Pivotal Role via the PI3K/Akt/mTOR Signaling Pathway in the Chronicity of Mesial Temporal Lobe Epilepsy

(2016) Zhaohua Xiao et al.   NEUROIMMUNOMODULATION

Somatic activating mutations in Pik3ca cause sporadic venous malformations in mice and humans

(2016) Sandra D. Castillo et al.   Science Translational Medicine

Somatic PIK3CA mutations as a driver of sporadic venous malformations

(2016) Pau Castel et al.   Science Translational Medicine

Epidemiological Study on Chronic Venous Disease in Belgium and Luxembourg: Prevalence, Risk Factors, and Symptomatology

(2015) M.E. Vuylsteke et al.   EUROPEAN JOURNAL OF VASCULAR AND ENDOVASCULAR SURGERY

PI3King the Lock

(2015) David King et al.   JOURNAL OF PEDIATRIC HEMATOLOGY ONCOLOGY

Targeting the PI3K/AKT/mTOR pathway in squamous cell carcinoma of the head and neck

(2015) Daniel R. Simpson et al.   ORAL ONCOLOGY

Hypoxia-Inducible Factor as an Angiogenic Master Switch

(2015) Takuya Hashimoto et al.   Frontiers in Pediatrics

Chronic Venous Insufficiency

(2014) Robert T. Eberhardt et al.   CIRCULATION

PI3K/Akt/uncoupling protein 2 signaling pathway may be involved in cell senescence and apoptosis induced by angiotensin II in human vascular endothelial cells

(2014) Ping Li et al.   MOLECULAR BIOLOGY REPORTS

Discovery and saturation analysis of cancer genes across 21 tumour types

(2014) Michael S. Lawrence et al.   NATURE

Novel Molecular Aspects of Ghrelin and Leptin in the Control of Adipobiology and the Cardiovascular System

(2014) Amaia Rodríguez   Obesity Facts

Long-term p110α PI3K inactivation exerts a beneficial effect on metabolism

(2013) Lazaros C. Foukas et al.   EMBO Molecular Medicine

Increased Expression of Hypoxia-Inducible Factor-1alpha and Bcl-2 in Varicocele and Varicose Veins

(2012) Jane-Dar Lee et al.   ANNALS OF VASCULAR SURGERY

Primer-BLAST: A tool to design target-specific primers for polymerase chain reaction

(2012) Jian Ye et al.   BMC BIOINFORMATICS

Flow control in our vessels: vascular valves make sure there is no way back

(2012) Eleni Bazigou et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Increased activation of the hypoxia-inducible factor pathway in varicose veins

(2012) Chung S. Lim et al.   JOURNAL OF VASCULAR SURGERY

Increased expression of hypoxia-inducible factor-1α and metallothionein in varicocele and varicose veins

(2012) J-D Lee et al.   PHLEBOLOGY

Clinical, Aetiological, Anatomical and Pathological Classification (Ceap): Gold Standard and Limits

(2012) E Rabe et al.   PHLEBOLOGY

Inflammation and apoptosis in aortic tissues of aged type II diabetes: Amelioration with α-lipoic acid through phosphatidylinositol 3-kinase/Akt- dependent mechanism

(2010) Milad S. Bitar et al.   LIFE SCIENCES

HIF-1 and HIF-2 transcription factors — Similar but not identical

(2010) Agnieszka Loboda et al.   MOLECULES AND CELLS

The inflammatory reaction during chronic venous disease of lower limbs.

(2009) Dominika Ojdana et al.   FOLIA HISTOCHEMICA ET CYTOBIOLOGICA

Updated terminology of chronic venous disorders: The VEIN-TERM transatlantic interdisciplinary consensus document

(2009) Bo Eklof et al.   JOURNAL OF VASCULAR SURGERY

Venous valves and major superficial tributary veins near the saphenofemoral junction

(2009) Dominic Mühlberger et al.   JOURNAL OF VASCULAR SURGERY