Molecular Mechanisms Underlying Curcumin-Mediated Therapeutic Effects in Type 2 Diabetes and Cancer

Inhibition of NF-κB translocation by curcumin analogs induces G0/G1 arrest and downregulates thymidylate synthase in colorectal cancer

(2016) Balney Rajitha et al.   CANCER LETTERS

Curcumin prevents inflammatory response, oxidative stress and insulin resistance in high fructose fed male Wistar rats: Potential role of serine kinases

(2016) Nachimuthu Maithilikarpagaselvi et al.   CHEMICO-BIOLOGICAL INTERACTIONS

Exploring the use of nanocarrier systems to deliver the magical molecule; Curcumin and its derivatives

(2016) Mina Mehanny et al.   JOURNAL OF CONTROLLED RELEASE

Molecular mechanisms underlying chemopreventive potential of curcumin: Current challenges and future perspectives

(2016) Gaurav Kumar et al.   LIFE SCIENCES

Novel synthetic curcumin analogs as potent antiangiogenic agents in colorectal cancer

(2016) Balney Rajitha et al.   MOLECULAR CARCINOGENESIS

The New Combination Docetaxel, Prednisone and Curcumin in Patients with Castration-Resistant Prostate Cancer: A Pilot Phase II Study

(2016) Hakim Mahammedi et al.   ONCOLOGY

Curcumin rescues high fat diet-induced obesity and insulin sensitivity in mice through regulating SREBP pathway

(2016) Lili Ding et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Curcumin attenuates palmitate-induced apoptosis in MIN6 pancreatic β-cells through PI3K/Akt/FoxO1 and mitochondrial survival pathways

(2015) Feng Hao et al.   APOPTOSIS

Curcumin promotes browning of white adipose tissue in a norepinephrine-dependent way

(2015) Shan Wang et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Curcumin promotes apoptosis by activating the p53-miR-192-5p/215-XIAP pathway in non-small cell lung cancer

(2015) Mingxiang Ye et al.   CANCER LETTERS

A Time to Kill: Targeting Apoptosis in Cancer

(2015) Jean Koff et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Curcumin: A pleiotropic phytonutrient in diabetic complications

(2015) Manish Kumar Jeenger et al.   NUTRITION

Obesity and Diabetes: The Increased Risk of Cancer and Cancer-Related Mortality

(2015) Emily Jane Gallagher et al.   PHYSIOLOGICAL REVIEWS

Curcumin suppresses migration and invasion of human endometrial carcinoma cells

(2015) QIAN CHEN et al.   Oncology Letters

Curcumin Conjugated with PLGA Potentiates Sustainability, Anti-Proliferative Activity and Apoptosis in Human Colon Carcinoma Cells

(2015) Bhargav N. Waghela et al.   PLoS One

Resveratrol potentiates the in vitro and in vivo anti-tumoral effects of curcumin in head and neck carcinomas

(2015) Laura Masuelli et al.   Oncotarget

Curcumin Inhibits MHCC97H Liver Cancer Cells by Activating ROS/TLR-4/Caspase Signaling Pathway

(2014) Pei-Min Li et al.   Asian Pacific Journal of Cancer Prevention

Anti-cancer activity of curcumin loaded nanoparticles in prostate cancer

(2014) Murali M. Yallapu et al.   BIOMATERIALS

Curcumin Induced Human Gastric Cancer BGC-823 Cells Apoptosis by ROS-Mediated ASK1-MKK4-JNK Stress Signaling Pathway

(2014) Tao Liang et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Resveratrol and curcumin enhance pancreatic β-cell function by inhibiting phosphodiesterase activity

(2014) Michael Rouse et al.   JOURNAL OF ENDOCRINOLOGY

Curcumin induces apoptosis through mitochondrial pathway and caspases activation in human melanoma cells

(2014) Ai-Jun Jiang et al.   MOLECULAR BIOLOGY REPORTS

pTyr421 Cortactin Is Overexpressed in Colon Cancer and Is Dephosphorylated by Curcumin: Involvement of Non-Receptor Type 1 Protein Tyrosine Phosphatase (PTPN1)

(2014) Vijayababu M. Radhakrishnan et al.   PLoS One

Drug Resistance in Cancer: An Overview

(2014) Genevieve Housman et al.   Cancers

Curcumin Inhibits TGF-β1-Induced MMP-9 and Invasion through ERK and Smad Signaling in Breast Cancer MDA-MB-231 Cells

(2013) Na Mo et al.   Asian Pacific Journal of Cancer Prevention

Curcumin Inhibits Human Non-small Cell Lung Cancer A549 Cell Proliferation Through Regulation of Bcl-2/Bax and Cytochrome C

(2013) Yue Li et al.   Asian Pacific Journal of Cancer Prevention

Curcumin Attenuates Diet-Induced Hepatic Steatosis by Activating AMP-Activated Protein Kinase

(2013) Min Young Um et al.   BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY

Angiogenesis and Vascular Functions in Modulation of Obesity, Adipose Metabolism, and Insulin Sensitivity

(2013) Yihai Cao   Cell Metabolism

Diabetes Mellitus and Inflammation

(2013) Eric Lontchi-Yimagou et al.   Current Diabetes Reports

AMPK, insulin resistance, and the metabolic syndrome

(2013) Neil B. Ruderman et al.   JOURNAL OF CLINICAL INVESTIGATION

Curcumin for Radiation Dermatitis: A Randomized, Double-Blind, Placebo-Controlled Clinical Trial of Thirty Breast Cancer Patients

(2013) Julie L. Ryan et al.   RADIATION RESEARCH

Curcumin induces osteosarcoma MG63 cells apoptosis via ROS/Cyto-C/Caspase-3 pathway

(2013) Zhengqi Chang et al.   TUMOR BIOLOGY

Curcumin Inhibits Tongue Carcinoma Cells Migration and Invasion Through Downregulation of Matrix Metallopeptidase 10

(2012) Raymond King-Yin Tsang et al.   CANCER INVESTIGATION

Curcumin Extract for Prevention of Type 2 Diabetes

(2012) S. Chuengsamarn et al.   DIABETES CARE

Curcuminoids exert glucose-lowering effect in type 2 diabetes by decreasing serum free fatty acids: a double-blind, placebo-controlled trial

(2012) Li-Xin Na et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Curcumin suppresses the TPA-induced invasion through inhibition of PKCα-dependent MMP-expression in MCF-7 human breast cancer cells

(2012) Jeong-Mi Kim et al.   PHYTOMEDICINE

Curcumin Prevents High Fat Diet Induced Insulin Resistance and Obesity via Attenuating Lipogenesis in Liver and Inflammatory Pathway in Adipocytes

(2012) Weijuan Shao et al.   PLoS One

Hallmarks of Cancer: The Next Generation

(2011) Douglas Hanahan et al.   CELL

The antihyperglycemic effect of curcumin in high fat diet fed rats. Role of TNF-α and free fatty acids

(2011) Mohamed A. El-Moselhy et al.   FOOD AND CHEMICAL TOXICOLOGY

Optimised nano-formulation on the bioavailability of hydrophobic polyphenol, curcumin, in freely-moving rats

(2011) Yin-Meng Tsai et al.   FOOD CHEMISTRY

Suppression of Free Fatty Acid-Induced Insulin Resistance by Phytopolyphenols in C2C12 Mouse Skeletal Muscle Cells

(2011) Yea-Tzy Deng et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Curcumin-induced suppression of adipogenic differentiation is accompanied by activation of Wnt/β-catenin signaling

(2010) Jiyun Ahn et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Phase I dose escalation trial of docetaxel plus curcumin in patients with advanced and metastatic breast cancer

(2010) Mathilde Bayet-Robert et al.   CANCER BIOLOGY & THERAPY

A phase I/II study of gemcitabine-based chemotherapy plus curcumin for patients with gemcitabine-resistant pancreatic cancer

(2010) Masashi Kanai et al.   CANCER CHEMOTHERAPY AND PHARMACOLOGY

Diabetes and Cancer: A consensus report

(2010) E. Giovannucci et al.   DIABETES CARE

Curcumin induces down-regulation of EZH2 expression through the MAPK pathway in MDA-MB-435 human breast cancer cells

(2010) Wen-Feng Hua et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Curcumin suppresses the dynamic instability of microtubules, activates the mitotic checkpoint and induces apoptosis in MCF-7 cells

(2010) Mithu Banerjee et al.   FEBS Journal

Synergistic effect of curcumin and insulin on muscle cell glucose metabolism

(2010) Changkeun Kang et al.   FOOD AND CHEMICAL TOXICOLOGY

Curcumin inhibits hepatic protein-tyrosine phosphatase 1B and prevents hypertriglyceridemia and hepatic steatosis in fructose-fed rats

(2010) Jian-Mei Li et al.   HEPATOLOGY

Curcumin, the Golden Spice From Indian Saffron, Is a Chemosensitizer and Radiosensitizer for Tumors and Chemoprotector and Radioprotector for Normal Organs

(2010) Ajay Goel et al.   NUTRITION AND CANCER-AN INTERNATIONAL JOURNAL

Curcumin improves insulin resistance in skeletal muscle of rats

(2010) L.-X. Na et al.   NUTRITION METABOLISM AND CARDIOVASCULAR DISEASES

Curcumin and Cancer Cells: How Many Ways Can Curry Kill Tumor Cells Selectively?

(2009) Jayaraj Ravindran et al.   AAPS Journal

Curcumin activates AMPK and suppresses gluconeogenic gene expression in hepatoma cells

(2009) Teayoun Kim et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Potent growth suppressive activity of curcumin in human breast cancer cells: Modulation of Wnt/β-catenin signaling

(2009) Chandra P. Prasad et al.   CHEMICO-BIOLOGICAL INTERACTIONS

Curcumin Inhibits Adipogenesis in 3T3-L1 Adipocytes and Angiogenesis and Obesity in C57/BL Mice

(2009) Asma Ejaz et al.   JOURNAL OF NUTRITION

Curcumin reduces the expression of Bcl-2 by upregulating miR-15a and miR-16 in MCF-7 cells

(2009) Jie Yang et al.   MEDICAL ONCOLOGY

Structure and physiological functions of the human peroxisome proliferator-activated receptor γ

(2008) Andrzej Zieleniak et al.   ARCHIVUM IMMUNOLOGIAE ET THERAPIAE EXPERIMENTALIS

Phase II Trial of Curcumin in Patients with Advanced Pancreatic Cancer

(2008) N. Dhillon et al.   CLINICAL CANCER RESEARCH

Dietary Curcumin Significantly Improves Obesity-Associated Inflammation and Diabetes in Mouse Models of Diabesity

(2008) Stuart P. Weisberg et al.   ENDOCRINOLOGY

Effect of curcumin supplementation on blood glucose, plasma insulin, and glucose homeostasis related enzyme activities in diabeticdb/dbmice

(2008) Kwon-Il Seo et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Curcumin and resveratrol inhibit nuclear factor-kappaB-mediated cytokine expression in adipocytes

(2008) Amanda M Gonzales et al.   Nutrition & Metabolism

Influences of weight loss on long-term diabetes outcomes

(2008) Lorna S. Aucott   PROCEEDINGS OF THE NUTRITION SOCIETY