Resveratrol-Induced Downregulation of NAF-1 Enhances the Sensitivity of Pancreatic Cancer Cells to Gemcitabine via the ROS/Nrf2 Signaling Pathways

Optimal dose reduction of FOLFIRINOX for preserving tumour response in advanced pancreatic cancer: Using cumulative relative dose intensity

(2017) Jong-chan Lee et al.   EUROPEAN JOURNAL OF CANCER

Targeted therapy of pancreatic cancer: biomarkers are needed

(2017) Jörg Kleeff et al.   LANCET ONCOLOGY

Activation of Nrf2 Signaling Augments Vesicular Stomatitis Virus Oncolysis via Autophagy-Driven Suppression of Antiviral Immunity

(2017) David Olagnier et al.   MOLECULAR THERAPY

Safety and efficacy of FOLFIRINOX in elderly patients with metastatic or locally advanced pancreatic adenocarcinoma: A retrospective analysis

(2017) C. Baldini et al.   PANCREATOLOGY

Resveratrol ameliorates myocardial fibrosis by inhibiting ROS/ERK/TGF-β/periostin pathway in STZ-induced diabetic mice

(2016) Han Wu et al.   BMC Cardiovascular Disorders

Resveratrol inhibits hyperglycemia-driven ROS-induced invasion and migration of pancreatic cancer cells via suppression of the ERK and p38 MAPK signaling pathways

(2016) Lei Cao et al.   INTERNATIONAL JOURNAL OF ONCOLOGY

Resveratrol Inhibits Proliferation, Invasion, and Epithelial-Mesenchymal Transition by Increasing miR-200c Expression in HCT-116 Colorectal Cancer Cells

(2016) Fatemeh Karimi Dermani et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Parenchymal and Stromal Cells Contribute to Pro-Inflammatory Myocardial Environment at Early Stages of Diabetes: Protective Role of Resveratrol

(2016) Monia Savi et al.   Nutrients

YAP Inhibition by Resveratrol via Activation of AMPK Enhances the Sensitivity of Pancreatic Cancer Cells to Gemcitabine

(2016) Zhengdong Jiang et al.   Nutrients

Resveratrol inhibits TIGAR to promote ROS induced apoptosis and autophagy

(2015) Bhupender Kumar et al.   BIOCHIMIE

Dual roles of NRF2 in tumor prevention and progression: Possible implications in cancer treatment

(2015) Eui Jung Moon et al.   FREE RADICAL BIOLOGY AND MEDICINE

Activation of apoptosis in NAF-1-deficient human epithelial breast cancer cells

(2015) Sarah H. Holt et al.   JOURNAL OF CELL SCIENCE

Resveratrol inhibits hypoxia-driven ROS-induced invasive and migratory ability of pancreatic cancer cells via suppression of the Hedgehog signaling pathway

(2015) WEI LI et al.   ONCOLOGY REPORTS

Cancer Cell Growth Is Differentially Affected by Constitutive Activation of NRF2 by KEAP1 Deletion and Pharmacological Activation of NRF2 by the Synthetic Triterpenoid, RTA 405

(2015) Brandon L. Probst et al.   PLoS One

The Fe-S cluster-containing NEET proteins mitoNEET and NAF-1 as chemotherapeutic targets in breast cancer

(2015) Fang Bai et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Overexpressed CISD2 has prognostic value in human gastric cancer and promotes gastric cancer cell proliferation and tumorigenesis via AKT signaling pathway

(2015) Lan Wang et al.   Oncotarget

Nrf2 Overexpression Predicts Prognosis and 5-FU Resistance in Gastric Cancer

(2014) Xiu-Feng Hu et al.   Asian Pacific Journal of Cancer Prevention

Projecting Cancer Incidence and Deaths to 2030: The Unexpected Burden of Thyroid, Liver, and Pancreas Cancers in the United States

(2014) L. Rahib et al.   CANCER RESEARCH

Cisd2 mediates lifespan: is there an interconnection among Ca2+homeostasis, autophagy, and lifespan?

(2014) C.-H. Wang et al.   FREE RADICAL RESEARCH

CISD2 expression is a novel marker correlating with pelvic lymph node metastasis and prognosis in patients with early-stage cervical cancer

(2014) Luxin Liu et al.   MEDICAL ONCOLOGY

Role of Nrf2 in Oxidative Stress and Toxicity

(2013) Qiang Ma   Annual Review of Pharmacology and Toxicology

Apigenin sensitizes doxorubicin-resistant hepatocellular carcinoma BEL-7402/ADM cells to doxorubicin via inhibiting PI3K/Akt/Nrf2 pathway

(2013) Ai-Mei Gao et al.   CARCINOGENESIS

Resveratrol Inhibits the Epithelial-Mesenchymal Transition of Pancreatic Cancer Cells Via Suppression of the PI-3K/Akt/NF-κB Pathway

(2013) Wei Li et al.   CURRENT MEDICINAL CHEMISTRY

The emerging role of the Nrf2-Keap1 signaling pathway in cancer

(2013) M. C. Jaramillo et al.   GENES & DEVELOPMENT

Resveratrol Suppresses Cancer Cell Glucose Uptake by Targeting Reactive Oxygen Species-Mediated Hypoxia-Inducible Factor-1  Activation

(2013) K.-H. Jung et al.   JOURNAL OF NUCLEAR MEDICINE

Nutrient-Deprivation Autophagy Factor-1 (NAF-1): Biochemical Properties of a Novel Cellular Target for Anti-Diabetic Drugs

(2013) Sagi Tamir et al.   PLoS One

NAF-1 and mitoNEET are central to human breast cancer proliferation by maintaining mitochondrial homeostasis and promoting tumor growth

(2013) Yang-Sung Sohn et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mechanisms of resistance to chemotherapeutic and anti-angiogenic drugs as novel targets for pancreatic cancer therapy

(2013) Anna Tamburrino et al.   Frontiers in Pharmacology

BCL2-CISD2

(2012) Natasha C. Chang et al.   Autophagy

The transcription factor NF-E2-related Factor 2 (Nrf2): a protooncogene?

(2012) Phillip Shelton et al.   FASEB JOURNAL

Green tea polyphenols function as prooxidants to inhibit Pseudomonas aeruginosa and induce the expression of oxidative stress-related genes

(2012) Xiaoxiang Liu et al.   FOLIA MICROBIOLOGICA

Upregulation of phase II enzymes through phytochemical activation of Nrf2 protects cardiomyocytes against oxidant stress

(2012) Danielle J. Reuland et al.   FREE RADICAL BIOLOGY AND MEDICINE

Resveratrol induces apoptosis via ROS-triggered autophagy in human colon cancer cells

(2012) HISANORI MIKI et al.   INTERNATIONAL JOURNAL OF ONCOLOGY

Resveratrol Inhibits Proliferation and Induces Apoptosis through the Hedgehog Signaling Pathway in Pancreatic Cancer Cell

(2012) Wenhui Mo et al.   PANCREATOLOGY

β2-adrenoceptor blocker synergizes with gemcitabine to inhibit the proliferation of pancreatic cancer cells via apoptosis induction

(2011) Tao Shan et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Molecular cross-talk between the NRF2/KEAP1 signaling pathway, autophagy, and apoptosis

(2011) Tomasz M. Stępkowski et al.   FREE RADICAL BIOLOGY AND MEDICINE

A role for the CISD2 gene in lifespan control and human disease

(2010) Yi-Fan Chen et al.   Annals of the New York Academy of Sciences

Cisd2 mediates mitochondrial integrity and life span in mammals

(2009) Yi-Fan Chen et al.   Autophagy

Nrf2: friend or foe for chemoprevention?

(2009) T. W. Kensler et al.   CARCINOGENESIS

Antagonism of Beclin 1-dependent autophagy by BCL-2 at the endoplasmic reticulum requires NAF-1

(2009) Natasha C Chang et al.   EMBO JOURNAL

Resveratrol protects primary rat hepatocytes against necrosis induced by reactive oxygen species

(2008) J.A. Rubiolo et al.   BIOMEDICINE & PHARMACOTHERAPY

Analyzing real-time PCR data by the comparative CT method

(2008) Thomas D Schmittgen et al.   Nature Protocols