Coenzyme Q10 Prevents Senescence and Dysfunction Caused by Oxidative Stress in Vascular Endothelial Cells

Oxidative Stress, Inflammation, and Vascular Aging in Hypertension

(2017) Tomasz J. Guzik et al.   HYPERTENSION

Coenzyme Q10 Improves Lipid Metabolism and Ameliorates Obesity by Regulating CaMKII-Mediated PDE4 Inhibition

(2017) Zhe Xu et al.   Scientific Reports

Vascular ageing and endothelial cell senescence: Molecular mechanisms of physiology and diseases

(2016) Carla Regina et al.   MECHANISMS OF AGEING AND DEVELOPMENT

ROS, Cell Senescence, and Novel Molecular Mechanisms in Aging and Age-Related Diseases

(2016) Pierpaola Davalli et al.   Oxidative Medicine and Cellular Longevity

Curcumin Attenuates Hydrogen Peroxide-Induced Premature Senescence via the Activation of SIRT1 in Human Umbilical Vein Endothelial Cells

(2015) Yueliu Sun et al.   BIOLOGICAL & PHARMACEUTICAL BULLETIN

Donepezil attenuates high glucose-accelerated senescence in human umbilical vein endothelial cells through SIRT1 activation

(2015) Tao Zhang et al.   CELL STRESS & CHAPERONES

Enhancer of zeste homolog 2 depletion induces cellular senescence via histone demethylation along the INK4/ARF locus

(2015) Bai Jie et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Coenzyme Q10 Inhibits the Aging of Mesenchymal Stem Cells Induced by D-Galactose through Akt/mTOR Signaling

(2015) Dayong Zhang et al.   Oxidative Medicine and Cellular Longevity

SIRT1-mediated epigenetic downregulation of plasminogen activator inhibitor-1 prevents vascular endothelial replicative senescence

(2014) Yan-Zhen Wan et al.   AGING CELL

MiR-92a regulates viability and angiogenesis of endothelial cells under oxidative stress

(2014) Lan Zhang et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Ginsenoside Rb1 Prevents H2O2-Induced HUVEC Senescence by Stimulating Sirtuin-1 Pathway

(2014) Zhiming Song et al.   PLoS One

Coenzyme Q10 Protects Human Endothelial Cells from β-Amyloid Uptake and Oxidative Stress-Induced Injury

(2014) Mario Durán-Prado et al.   PLoS One

Telomeres, cardiovascular aging, and potential intervention for cellular senescence

(2014) WeiLi Zhang et al.   Science China-Life Sciences

Gold Nanoparticles Inhibit VEGF165-Induced Migration and Tube Formation of Endothelial Cells via the Akt Pathway

(2014) Yunlong Pan et al.   Biomed Research International

Ubiquinol-10 Supplementation Activates Mitochondria Functions to Decelerate Senescence in Senescence-Accelerated Mice

(2013) Geng Tian et al.   ANTIOXIDANTS & REDOX SIGNALING

SIRT1 inhibits NADPH oxidase activation and protects endothelial function in the rat aorta: Implications for vascular aging

(2013) María José Zarzuelo et al.   BIOCHEMICAL PHARMACOLOGY

Ubiad1 Is an Antioxidant Enzyme that Regulates eNOS Activity by CoQ10 Synthesis

(2013) Vera Mugoni et al.   CELL

Anti-inflammatory effect of ubiquinol-10 on young and senescent endothelial cells via miR-146a modulation

(2013) Fabiola Olivieri et al.   FREE RADICAL BIOLOGY AND MEDICINE

Management of multicellular senescence and oxidative stress

(2013) David D. Haines et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Induction of G2/M phase cell cycle arrest and apoptosis by ginsenoside Rf in human osteosarcoma MG-63 cells through the mitochondrial pathway

(2013) WEN-JI SHANGGUAN et al.   ONCOLOGY REPORTS

Low concentrations of isothiocyanates protect mesenchymal stem cells from oxidative injuries, while high concentrations exacerbate DNA damage

(2012) Fulvia Zanichelli et al.   APOPTOSIS

Mortality from ischaemic heart disease by country, region, and age: Statistics from World Health Organisation and United Nations

(2012) Judith A. Finegold et al.   INTERNATIONAL JOURNAL OF CARDIOLOGY

Relationship between Human Aging Muscle and Oxidative System Pathway

(2012) Enrico Doria et al.   Oxidative Medicine and Cellular Longevity

Acute Activation of AMP-Activated Protein Kinase Prevents H2O2-Induced Premature Senescence in Primary Human Keratinocytes

(2012) Yasuo Ido et al.   PLoS One

Role of TRPM2 in H2O2-Induced Cell Apoptosis in Endothelial Cells

(2012) Lei Sun et al.   PLoS One

Oral advanced glycation endproducts (AGEs) promote insulin resistance and diabetes by depleting the antioxidant defenses AGE receptor-1 and sirtuin 1

(2012) W. Cai et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Rosuvastatin combined with regular exercise preserves coenzyme Q10 levels associated with a significant increase in high-density lipoprotein cholesterol in patients with coronary artery disease

(2011) Kensuke Toyama et al.   ATHEROSCLEROSIS

Reversal of mitochondrial dysfunction by coenzyme Q10 supplement improves endothelial function in patients with ischaemic left ventricular systolic dysfunction: A randomized controlled trial

(2011) Yuk-Ling Dai et al.   ATHEROSCLEROSIS

A blood flow-dependent klf2a-NO signaling cascade is required for stabilization of hematopoietic stem cell programming in zebrafish embryos

(2011) L. Wang et al.   BLOOD

Aging and vascular endothelial function in humans

(2011) Douglas R. Seals et al.   CLINICAL SCIENCE

Nitric oxide synthases: regulation and function

(2011) U. Forstermann et al.   EUROPEAN HEART JOURNAL

MicroRNA changes in human arterial endothelial cells with senescence: Relation to apoptosis, eNOS and inflammation

(2011) Catarina Rippe et al.   EXPERIMENTAL GERONTOLOGY

SIRT1/eNOS Axis as a Potential Target against Vascular Senescence, Dysfunction and Atherosclerosis

(2011) Hidetaka Ota et al.   Journal of Atherosclerosis and Thrombosis

The role of SirT1 in muscle mitochondrial turnover

(2011) Keir J. Menzies et al.   MITOCHONDRION

Glucagon-Like Peptide 1 Prevents Reactive Oxygen Species–Induced Endothelial Cell Senescence Through the Activation of Protein Kinase A

(2010) Hisko Oeseburg et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

SIRT1 regulates oxidant- and cigarette smoke-induced eNOS acetylation in endothelial cells: Role of resveratrol

(2010) Gnanapragasam Arunachalam et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Coenzyme Q – Biosynthesis and functions

(2010) Magnus Bentinger et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Sirt3 Mediates Reduction of Oxidative Damage and Prevention of Age-Related Hearing Loss under Caloric Restriction

(2010) Shinichi Someya et al.   CELL

Preparation and characterization of liposomal coenzyme Q10 for in vivo topical application

(2010) Wen-Chuan Lee et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Cellular signaling and NO production

(2010) Thomas Michel et al.   PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY

Inflammatory networks during cellular senescence: causes and consequences

(2010) Adam Freund et al.   TRENDS IN MOLECULAR MEDICINE

The evolution of coenzyme Q

(2009) Frederick L. Crane   BIOFACTORS

Nuclear Factor-κB Activation Contributes to Vascular Endothelial Dysfunction via Oxidative Stress in Overweight/Obese Middle-Aged and Older Humans

(2009) Gary L. Pierce et al.   CIRCULATION

Chemokine Signaling via the CXCR2 Receptor Reinforces Senescence

(2008) Juan C. Acosta et al.   CELL

Bradykinin Protects Against Oxidative Stress–Induced Endothelial Cell Senescence

(2008) Hisko Oeseburg et al.   HYPERTENSION

An Oncogene-Induced DNA Damage Model for Cancer Development

(2008) T. D. Halazonetis et al.   SCIENCE