Management of multicellular senescence and oxidative stress

mTOR's role in ageing: protein synthesis or autophagy?

(2016) Sarah L. Hands et al.   Aging-US

Progeria, rapamycin and normal aging: recent breakthrough

(2016) Mikhail V. Blagosklonny   Aging-US

Everolimus in colorectal cancer

(2013) Ivy Altomare et al.   EXPERT OPINION ON PHARMACOTHERAPY

Telocytes: ultrastructural, immunohistochemical and electrophysiological characteristics in human myometrium

(2013) Sanda M Cretoiu et al.   REPRODUCTION

Cardiac telocytes were decreased during myocardial infarction and their therapeutic effects for ischaemic heart in rat

(2012) Baoyin Zhao et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Human myometrium - the ultrastructural 3D network of telocytes

(2012) Sanda M. Creţoiu et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Rapamycin protects against myocardial ischemia–reperfusion injury through JAK2–STAT3 signaling pathway

(2012) Anindita Das et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Evolutionary Meaning of Non-Synchronous Medusa Release and Spawning in the Most Advanced Bivalve-Inhabiting Hydrozoan,Eugymnanthea japonica

(2012) Shin Kubota   ZOOLOGICAL SCIENCE

Rapamycin and other longevity-promoting compounds enhance the generation of mouse induced pluripotent stem cells

(2011) Taotao Chen et al.   AGING CELL

Involvement of Creatine Kinase B in Cigarette Smoke–Induced Bronchial Epithelial Cell Senescence

(2011) Hiromichi Hara et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Hallmarks of Cancer: The Next Generation

(2011) Douglas Hanahan et al.   CELL

Rapamycin decelerates cellular senescence

(2011) Zoya N. Demidenko et al.   CELL CYCLE

Pseudo-DNA damage response in senescent cells

(2011) Tatyana V. Pospelova et al.   CELL CYCLE

Necroptosis, necrostatins and tissue injury

(2011) Christopher C.T. Smith et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Cells Derived from Young Bone Marrow Alleviate Renal Aging

(2011) H.-C. Yang et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Caloric restriction

(2011) John R. Speakman et al.   MOLECULAR ASPECTS OF MEDICINE

Clearance of p16Ink4a-positive senescent cells delays ageing-associated disorders

(2011) Darren J. Baker et al.   NATURE

Evaluation of Systemic and Dermal Toxicity and Dermal Photoprotection by Sour Cherry Kernels

(2011) Istvan Bak et al.   PHYTOTHERAPY RESEARCH

5′-Adenosine Monophosphate-Activated Protein Kinase–Mammalian Target of Rapamycin Axis As Therapeutic Target for Age-Related Macular Degeneration

(2011) Juha M.T. Hyttinen et al.   REJUVENATION RESEARCH

Rapamycin Reverses Cellular Phenotypes and Enhances Mutant Protein Clearance in Hutchinson-Gilford Progeria Syndrome Cells

(2011) K. Cao et al.   Science Translational Medicine

Preconditioning by Phosphodiesterase-5 Inhibition Improves Therapeutic Efficacy of Adipose-Derived Stem Cells Following Myocardial Infarction in Mice

(2011) Nicholas N. Hoke et al.   STEM CELLS

Postconditioning and protection from reperfusion injury: where do we stand? * Position Paper from the Working Group of Cellular Biology of the Heart of the European Society of Cardiology

(2010) M. Ovize et al.   CARDIOVASCULAR RESEARCH

Epigenetic profiles in primordial germ cells: Global modulation and fine tuning of the epigenome for acquisition of totipotency

(2010) Kentaro Mochizuki et al.   DEVELOPMENT GROWTH & DIFFERENTIATION

Chemical Inducers of Autophagy That Enhance the Clearance of Mutant Proteins in Neurodegenerative Diseases

(2010) Maurizio Renna et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Role of progerin-induced telomere dysfunction in HGPS premature cellular senescence

(2010) E. K. Benson et al.   JOURNAL OF CELL SCIENCE

Telocytes in human isolated atrial amyloidosis: ultrastructural remodelling

(2010) E. Mandache et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Does autophagy take a front seat in lifespan extension?

(2010) Goran Petrovski et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Regenerative medicine: then and now - an update of recent history into future possibilities

(2010) E. Polykandriotis et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Epigenetic Basis for Fetal Origins of Age-Related Disease

(2010) Reid F. Thompson et al.   JOURNAL OF WOMENS HEALTH

Telomerase reactivation reverses tissue degeneration in aged telomerase-deficient mice

(2010) Mariela Jaskelioff et al.   NATURE

Progeria syndromes and ageing: what is the connection?

(2010) Christopher R. Burtner et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Low-dose oral sirolimus reduces atherogenesis, vascular inflammation and modulates plaque composition in mice lacking the LDL receptor

(2009) L Zhao et al.   BRITISH JOURNAL OF PHARMACOLOGY

Necroptosis, necrosis and secondary necrosis converge on similar cellular disintegration features

(2009) T Vanden Berghe et al.   CELL DEATH AND DIFFERENTIATION

Proteomic analysis of protein complexes in human SH-SY5Y neuroblastoma cells by using blue-native gel electrophoresis: An increase in lamin A/C associated with heat shock protein 90 in response to 6-hydroxydopamine-induced oxidative stress

(2009) Megumi Nakamura et al.   EXPERIMENTAL GERONTOLOGY

Placental-derived and expanded mesenchymal stromal cells (PLX-I) to enhance the engraftment of hematopoietic stem cells derived from umbilical cord blood

(2008) William R Prather et al.   EXPERT OPINION ON BIOLOGICAL THERAPY

Lamin A-dependent misregulation of adult stem cells associated with accelerated ageing

(2008) Paola Scaffidi et al.   NATURE CELL BIOLOGY

Prevention of atherosclerosis by the mTOR inhibitor everolimus in LDLR−/− mice despite severe hypercholesterolemia

(2007) Marc A. Mueller et al.   ATHEROSCLEROSIS