Genome Annotation by Shotgun Inactivation of a Native Gene in Hemizygous Cells: Application toBRCA2with Implication of Hypomorphic Variants

BRCA2 Phosphorylated by PLK1 Moves to the Midbody to Regulate Cytokinesis Mediated by Nonmuscle Myosin IIC

(2014) M. Takaoka et al.   CANCER RESEARCH

Two Decades After BRCA: Setting Paradigms in Personalized Cancer Care and Prevention

(2014) F. J. Couch et al.   SCIENCE

A robust TALENs system for highly efficient mammalian genome editing

(2014) Yuanxi Feng et al.   Scientific Reports

Hypersensitivities for Acetaldehyde and Other Agents among Cancer Cells Null for Clinically Relevant Fanconi Anemia Genes

(2013) Soma Ghosh et al.   AMERICAN JOURNAL OF PATHOLOGY

High-efficiency and heritable gene targeting in mouse by transcription activator-like effector nucleases

(2013) Zhongwei Qiu et al.   NUCLEIC ACIDS RESEARCH

BRCA2 Localization to the Midbody by Filamin A Regulates CEP55 Signaling and Completion of Cytokinesis

(2012) Gourish Mondal et al.   DEVELOPMENTAL CELL

The Causes and Consequences of Polyploidy in Normal Development and Cancer

(2011) Teresa Davoli et al.   Annual Review of Cell and Developmental Biology

Genetic engineering of human pluripotent cells using TALE nucleases

(2011) Dirk Hockemeyer et al.   NATURE BIOTECHNOLOGY

Two classes of BRC repeats in BRCA2 promote RAD51 nucleoprotein filament function by distinct mechanisms

(2011) A. Carreira et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Evidence that the tumor-suppressor protein BRCA2 does not regulate cytokinesis in human cells

(2010) S. Lekomtsev et al.   JOURNAL OF CELL SCIENCE

A Syngeneic Variance Library for Functional Annotation of Human Variation: Application to BRCA2

(2008) T. Hucl et al.   CANCER RESEARCH

Investigating the role of Aurora kinases in RAS signaling

(2008) Audrey Kosik et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Mouse embryonic stem cell–based functional assay to evaluate mutations in BRCA2

(2008) Sergey G Kuznetsov et al.   NATURE MEDICINE