Altering 5-hydroxymethylcytosine modification impacts ischemic brain injury

Role of vascular endothelial growth factor and other growth factors in post-stroke recovery

(2014) Madakasira VasanthaPadma Srivastava et al.   Annals of Indian Academy of Neurology

Tenascin-C is increased in atherothrombotic stroke patients and has an anti-inflammatory effect in the human carotid artery

(2014) Paula Clancy et al.   BIOFACTORS

Dynamic expression changes of Bcl-2, Caspase-3 and Hsp70 in middle cerebral artery occlusion rats

(2014) Xiaoping Wang et al.   BRAIN INJURY

Unlocking epigenetic codes in neurogenesis

(2014) B. Yao et al.   GENES & DEVELOPMENT

Serum Brain-derived neurotrophic factor levels in post-stroke depression

(2014) Jie Li et al.   JOURNAL OF AFFECTIVE DISORDERS

Tim-3 cell signaling and iNOS are involved in the protective effects of ischemic postconditioning against focal ischemia in rats

(2014) Dingtai Wei et al.   METABOLIC BRAIN DISEASE

Induction of Transforming Growth Factor Beta Receptors following Focal Ischemia in the Rat Brain

(2014) Gabriella Pál et al.   PLoS One

Analysis of the expression of nine secreted matrix metalloproteinases and their endogenous inhibitors in the brain of mice subjected to ischaemic stroke

(2014) Sébastien Lenglet et al.   THROMBOSIS AND HAEMOSTASIS

Genome-wide alteration of 5-hydroxymethylcytosine in a mouse model of fragile X-associated tremor/ataxia syndrome

(2013) Bing Yao et al.   HUMAN MOLECULAR GENETICS

Genome-wide loss of 5-hmC is a novel epigenetic feature of Huntington's disease

(2013) Fengli Wang et al.   HUMAN MOLECULAR GENETICS

Ascorbate Induces Ten-Eleven Translocation (Tet) Methylcytosine Dioxygenase-mediated Generation of 5-Hydroxymethylcytosine

(2013) Emily A. Minor et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Consistent decrease in global DNA methylation and hydroxymethylation in the hippocampus of Alzheimer's disease patients

(2013) Leonidas Chouliaras et al.   NEUROBIOLOGY OF AGING

Reduction of DNA hydroxymethylation in the mouse kidney insulted by ischemia reperfusion

(2012) Ning Huang et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Base-Resolution Analysis of 5-Hydroxymethylcytosine in the Mammalian Genome

(2012) Miao Yu et al.   CELL

Genome-wide DNA hydroxymethylation changes are associated with neurodevelopmental genes in the developing human cerebellum

(2012) Tao Wang et al.   HUMAN MOLECULAR GENETICS

A natural coumarin derivative esculetin offers neuroprotection on cerebral ischemia/reperfusion injury in mice

(2012) Chen Wang et al.   JOURNAL OF NEUROCHEMISTRY

Hypoxic preconditioning induces stroke tolerance in mice via a cascading HIF, sphingosine kinase, and CCL2 signaling pathway

(2012) Bradley K. Wacker et al.   JOURNAL OF NEUROCHEMISTRY

Effect of Focal Ischemia on Long Noncoding RNAs

(2012) Ashutosh Dharap et al.   STROKE

Deletion of Tet2 in mice leads to dysregulated hematopoietic stem cells and subsequent development of myeloid malignancies

(2011) Z. Li et al.   BLOOD

TET2 Inactivation Results in Pleiotropic Hematopoietic Abnormalities in Mouse and Is a Recurrent Event during Human Lymphomagenesis

(2011) Cyril Quivoron et al.   CANCER CELL

Oncometabolite 2-Hydroxyglutarate Is a Competitive Inhibitor of α-Ketoglutarate-Dependent Dioxygenases

(2011) Wei Xu et al.   CANCER CELL

Prediction of novel families of enzymes involved in oxidative and other complex modifications of bases in nucleic acids

(2011) Lakshminarayan M. Iyer et al.   CELL CYCLE

Lineage-specific distribution of high levels of genomic

(2011) Alexey Ruzov et al.   CELL RESEARCH

Two novel mutations of the IRX4 gene in patients with congenital heart disease

(2011) Zhi Cheng et al.   HUMAN GENETICS

Genome-wide mapping of 5-hydroxymethylcytosine in embryonic stem cells

(2011) William A. Pastor et al.   NATURE

Dynamic regulation of 5-hydroxymethylcytosine in mouse ES cells and during differentiation

(2011) Gabriella Ficz et al.   NATURE

5-hmC–mediated epigenetic dynamics during postnatal neurodevelopment and aging

(2011) Keith E Szulwach et al.   NATURE NEUROSCIENCE

Genetic Determinants of Cardiovascular Events among Women with Migraine: A Genome-Wide Association Study

(2011) Markus Schürks et al.   PLoS One

Ten-Eleven-Translocation 2 (TET2) negatively regulates homeostasis and differentiation of hematopoietic stem cells in mice

(2011) M. Ko et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Emerging Role of Epigenetics in Stroke

(2010) Irfan A. Qureshi et al.   ARCHIVES OF NEUROLOGY

Role of Tet proteins in 5mC to 5hmC conversion, ES-cell self-renewal and inner cell mass specification

(2010) Shinsuke Ito et al.   NATURE

Selective chemical labeling reveals the genome-wide distribution of 5-hydroxymethylcytosine

(2010) Chun-Xiao Song et al.   NATURE BIOTECHNOLOGY

Conversion of 5-Methylcytosine to 5-Hydroxymethylcytosine in Mammalian DNA by MLL Partner TET1

(2009) M. Tahiliani et al.   SCIENCE

The Nuclear DNA Base 5-Hydroxymethylcytosine Is Present in Purkinje Neurons and the Brain

(2009) S. Kriaucionis et al.   SCIENCE

Neuroprotective effect of humanin on cerebral ischemia/reperfusion injury is mediated by a PI3K/Akt pathway

(2008) Xingshun Xu et al.   BRAIN RESEARCH

Duane's retraction syndrome as a cause of diplopia in adults

(2008) J. H. Kim et al.   EUROPEAN JOURNAL OF NEUROLOGY

Epigenetic regulation of the estrogen receptor alpha promoter in the cerebral cortex following ischemia in male and female rats

(2008) J.M. Westberry et al.   NEUROSCIENCE