Hypoxic preconditioning induces stroke tolerance in mice via a cascading HIF, sphingosine kinase, and CCL2 signaling pathway

Hypoxia-Inducible Factors and Sphingosine 1-Phosphate Signaling

(2012) Olivier Cuvillier et al.   Anti-Cancer Agents in Medicinal Chemistry

Junctional Protein Regulation by Sphingosine Kinase 2 Contributes to Blood–Brain Barrier Protection in Hypoxic Preconditioning-Induced Cerebral Ischemic Tolerance

(2012) Bradley K Wacker et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

CCL2 upregulation triggers hypoxic preconditioning-induced protection from stroke

(2012) Ann M Stowe et al.   Journal of Neuroinflammation

Adaptive and Maladaptive Cardiorespiratory Responses to Continuous and Intermittent Hypoxia Mediated by Hypoxia-Inducible Factors 1 and 2

(2012) Nanduri R. Prabhakar et al.   PHYSIOLOGICAL REVIEWS

Repetitive hypoxia extends endogenous neurovascular protection for stroke

(2011) Ann M. Stowe et al.   ANNALS OF NEUROLOGY

Sphingosine kinase 1 pathway is involved in melatonin-induced HIF-1α inactivation in hypoxic PC-3 prostate cancer cells

(2011) Sung-Yun Cho et al.   JOURNAL OF PINEAL RESEARCH

Sphingosine Kinase 2 Mediates Cerebral Preconditioning and Protects the Mouse Brain Against Ischemic Injury

(2011) Lai Ming Yung et al.   STROKE

Can Genes Modify Stroke Outcome and By What Mechanisms?

(2011) Roger P. Simon et al.   STROKE

Monocyte Chemoattractant Protein–1 Released from Alveolar Macrophages Mediates the Systemic Inflammation of Acute Alveolar Hypoxia

(2010) Jie Chao et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Protein S controls hypoxic/ischemic blood-brain barrier disruption through the TAM receptor Tyro3 and sphingosine 1-phosphate receptor

(2010) D. Zhu et al.   BLOOD

Sphingosine-1-Phosphate Receptor 3 Promotes Recruitment of Monocyte/Macrophages in Inflammation and Atherosclerosis

(2010) Petra Keul et al.   CIRCULATION RESEARCH

The involvement of sphingosine kinase 1 in LPS-induced Toll-like receptor 4-mediated accumulation of HIF-1α protein, activation of ASK1 and production of the pro-inflammatory cytokine IL-6

(2010) Dmitri Pchejetski et al.   IMMUNOLOGY AND CELL BIOLOGY

Essential roles of sphingosine-1–phosphate receptor 2 in human mast cell activation, anaphylaxis, and pulmonary edema

(2010) Carole A. Oskeritzian et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Sphingosine-1-Phosphate

(2009) Maude D. Michaud et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

When the Sphingosine Kinase 1/Sphingosine 1-Phosphate Pathway Meets Hypoxia Signaling: New Targets for Cancer Therapy

(2009) I. Ader et al.   CANCER RESEARCH

Oxygen Sensors at the Crossroad of Metabolism

(2009) Julián Aragonés et al.   Cell Metabolism

Hypoxia-inducible factor 1: a new hope to counteract neurodegeneration?

(2009) Sónia C. Correia et al.   JOURNAL OF NEUROCHEMISTRY

Hypoxia Enhances Sphingosine Kinase 2 Activity and Provokes Sphingosine-1-Phosphate-Mediated Chemoresistance in A549 Lung Cancer Cells

(2009) S. E. Schnitzer et al.   MOLECULAR CANCER RESEARCH

Regulation of Oxygen Homeostasis by Hypoxia-Inducible Factor 1

(2009) Gregg L. Semenza   PHYSIOLOGY

Hypoxic Preconditioning-Induced Cerebral Ischemic Tolerance

(2009) Bradley K. Wacker et al.   STROKE

Sphingosine kinase-1 is a hypoxia-regulated gene that stimulates migration of human endothelial cells

(2008) Stephanie Schwalm et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Distinct roles of sphingosine kinases 1 and 2 in human mast-cell functions

(2008) C. A. Oskeritzian et al.   BLOOD

Sphingosine Kinase 1: A New Modulator of Hypoxia Inducible Factor 1  during Hypoxia in Human Cancer Cells

(2008) I. Ader et al.   CANCER RESEARCH

Monocyte Chemotactic Protein (MCP)-1 Promotes Angiogenesis via a Novel Transcription Factor, MCP-1-induced Protein (MCPIP)

(2008) Jianli Niu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY