Irf6 directly regulates Klf17 in zebrafish periderm and Klf4 in murine oral epithelium, and dominant-negative KLF4 variants are present in patients with cleft lip and palate

Identification of Functional Variants for Cleft Lip with or without Cleft Palate in or near PAX7, FGFR2, and NOG by Targeted Sequencing of GWAS Loci

(2015) Elizabeth J. Leslie et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Genome-wide analysis of the zebrafish Klf family identifies two genes important for erythroid maturation

(2015) Yuanyuan Xue et al.   DEVELOPMENTAL BIOLOGY

Toward an orofacial gene regulatory network

(2015) Youssef A. Kousa et al.   DEVELOPMENTAL DYNAMICS

Pioneer factors govern super-enhancer dynamics in stem cell plasticity and lineage choice

(2015) Rene C. Adam et al.   NATURE

Genome-wide association study identifies a new susceptibility locus for cleft lip with or without a cleft palate

(2015) Yimin Sun et al.   Nature Communications

Periderm prevents pathological epithelial adhesions during embryogenesis

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Basal Keratinocytes Contribute to All Strata of the Adult Zebrafish Epidermis

(2014) Raymond T. H. Lee et al.   PLoS One

Dominant Mutations in GRHL3 Cause Van der Woude Syndrome and Disrupt Oral Periderm Development

(2013) Myriam Peyrard-Janvid et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Genetics of cleft lip and cleft palate

(2013) Elizabeth J. Leslie et al.   AMERICAN JOURNAL OF MEDICAL GENETICS PART C-SEMINARS IN MEDICAL GENETICS

Master Transcription Factors and Mediator Establish Super-Enhancers at Key Cell Identity Genes

(2013) Warren A. Whyte et al.   CELL

A Pou5f1/Oct4 dependent Klf2a, Klf2b, and Klf17 regulatory sub-network contributes to EVL and ectoderm development during zebrafish embryogenesis

(2013) Kay Kotkamp et al.   DEVELOPMENTAL BIOLOGY

Gene regulatory evolution and the origin of macroevolutionary novelties: Insights from the neural crest

(2013) Eric Van Otterloo et al.   GENESIS

JASPAR 2014: an extensively expanded and updated open-access database of transcription factor binding profiles

(2013) Anthony Mathelier et al.   NUCLEIC ACIDS RESEARCH

The Evolution of Human Genetic Studies of Cleft Lip and Cleft Palate

(2012) Mary L. Marazita   Annual Review of Genomics and Human Genetics

Extensive Promoter-Centered Chromatin Interactions Provide a Topological Basis for Transcription Regulation

(2012) Guoliang Li et al.   CELL

Evaluating rare coding variants as contributing causes to non-syndromic cleft lip and palate

(2012) EJ Leslie et al.   CLINICAL GENETICS

Interferon Regulatory Factor 6 Promotes Differentiation of the Periderm by Activating Expression of Grainyhead-Like 3

(2012) Gabriel de la Garza et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Kruppel-Like Factor 1 (KLF1), KLF2, and Myc Control a Regulatory Network Essential for Embryonic Erythropoiesis

(2012) C. J. Pang et al.   MOLECULAR AND CELLULAR BIOLOGY

An integrated encyclopedia of DNA elements in the human genome

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Genome-wide meta-analyses of nonsyndromic cleft lip with or without cleft palate identify six new risk loci

(2012) Kerstin U Ludwig et al.   NATURE GENETICS

Genetics of Nonsyndromic Orofacial Clefts

(2011) Fedik Rahimov et al.   CLEFT PALATE-CRANIOFACIAL JOURNAL

The GUDMAP database - an online resource for genitourinary research

(2011) S. D. Harding et al.   DEVELOPMENT

Lack of the ventral anterior homeodomain transcription factor VAX1 leads to induction of a second pituitary

(2011) K. Bharti et al.   DEVELOPMENT

Interferon Regulatory Factor 6 Is Necessary, but Not Sufficient, for Keratinocyte Differentiation

(2011) Leah C. Biggs et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Zebrafish Krüppel-Like Factor 4a Represses Intestinal Cell Proliferation and Promotes Differentiation of Intestinal Cell Lineages

(2011) I-Chen Li et al.   PLoS One

Developmental factor IRF6 exhibits tumor suppressor activity in squamous cell carcinomas

(2011) E. Botti et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A New Testing Strategy to Identify Rare Variants with Either Risk or Protective Effect on Disease

(2011) Iuliana Ionita-Laza et al.   PLoS Genetics

Testing for an Unusual Distribution of Rare Variants

(2011) Benjamin M. Neale et al.   PLoS Genetics

Pooled Association Tests for Rare Variants in Exon-Resequencing Studies

(2010) Alkes L. Price et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Deriving the consequences of genomic variants with the Ensembl API and SNP Effect Predictor

(2010) William McLaren et al.   BIOINFORMATICS

A genome-wide association study of cleft lip with and without cleft palate identifies risk variants near MAFB and ABCA4

(2010) Terri H Beaty et al.   NATURE GENETICS

Mammalian Krüppel-Like Factors in Health and Diseases

(2010) Beth B. McConnell et al.   PHYSIOLOGICAL REVIEWS

Zebrafish enhancer detection (ZED) vector: A new tool to facilitate transgenesis and the functional analysis ofcis-regulatory regions in zebrafish

(2009) José Bessa et al.   DEVELOPMENTAL DYNAMICS

FOXE1 association with both isolated cleft lip with or without cleft palate, and isolated cleft palate

(2009) Lina M. Moreno et al.   HUMAN MOLECULAR GENETICS

A Genome-Wide Association Study Identifies a Locus for Nonsyndromic Cleft Lip with or without Cleft Palate on 8q24

(2009) Struan F.A. Grant et al.   JOURNAL OF PEDIATRICS

Finding the missing heritability of complex diseases

(2009) Teri A. Manolio et al.   NATURE

Genome-wide association study identifies two susceptibility loci for nonsyndromic cleft lip with or without cleft palate

(2009) Elisabeth Mangold et al.   NATURE GENETICS

Key susceptibility locus for nonsyndromic cleft lip with or without cleft palate on chromosome 8q24

(2009) Stefanie Birnbaum et al.   NATURE GENETICS

Maternal Interferon Regulatory Factor 6 is required for the differentiation of primary superficial epithelia in Danio and Xenopus embryos

(2008) Jaime L. Sabel et al.   DEVELOPMENTAL BIOLOGY

A Network of Krüppel-like Factors (Klfs)

(2008) Sally A. Eaton et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Personal genomes: The case of the missing heritability

(2008) Brendan Maher   NATURE

The Krüppel-like factor 9 (KLF9) network in HEC-1-A endometrial carcinoma cells suggests the carcinogenic potential of dys-regulated KLF9 expression

(2008) Frank A Simmen et al.   Reproductive Biology and Endocrinology

Model-based Analysis of ChIP-Seq (MACS)

(2008) Yong Zhang et al.   GENOME BIOLOGY