Kruppel-Like Factor 1 (KLF1), KLF2, and Myc Control a Regulatory Network Essential for Embryonic Erythropoiesis

Single-lineage transcriptome analysis reveals key regulatory pathways in primitive erythroid progenitors in the mouse embryo

(2011) J. Isern et al.   BLOOD

Genome-wide ChIP-Seq reveals a dramatic shift in the binding of the transcription factor erythroid Kruppel-like factor during erythrocyte differentiation

(2011) A. M. Pilon et al.   BLOOD

Krüppel-like factor 2 regulated gene expression in mouse embryonic yolk sac erythroid cells

(2011) Latasha C. Redmond et al.   BLOOD CELLS MOLECULES AND DISEASES

Transcription Factors KLF1 and KLF2 Positively Regulate Embryonic and Fetal β-Globin Genes through Direct Promoter Binding

(2011) Yousef N. Alhashem et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A Dominant Mutation in the Gene Encoding the Erythroid Transcription Factor KLF1 Causes a Congenital Dyserythropoietic Anemia

(2010) Lionel Arnaud et al.   AMERICAN JOURNAL OF HUMAN GENETICS

A global role for KLF1 in erythropoiesis revealed by ChIP-seq in primary erythroid cells

(2010) M. R. Tallack et al.   GENOME RESEARCH

Down-regulation of Myc Is Essential for Terminal Erythroid Maturation

(2010) Senthil Raja Jayapal et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Haploinsufficiency for the erythroid transcription factor KLF1 causes hereditary persistence of fetal hemoglobin

(2010) Joseph Borg et al.   NATURE GENETICS

KLF1 regulates BCL11A expression and γ- to β-globin gene switching

(2010) Dewang Zhou et al.   NATURE GENETICS

Mammalian Krüppel-Like Factors in Health and Diseases

(2010) Beth B. McConnell et al.   PHYSIOLOGICAL REVIEWS

C-myc as a modulator of renal stem/progenitor cell population

(2009) Martin Couillard et al.   DEVELOPMENTAL DYNAMICS

EKLF/KLF1 Controls Cell Cycle Entry via Direct Regulation of E2f2

(2009) Michael R. Tallack et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Preferential associations between co-regulated genes reveal a transcriptional interactome in erythroid cells

(2009) Stefan Schoenfelder et al.   NATURE GENETICS

Placental rescue reveals a sole requirement for c-Myc in embryonic erythroblast survival and hematopoietic stem cell function

(2008) N. C. Dubois et al.   DEVELOPMENT

c-myc in the hematopoietic lineage is crucial for its angiogenic function in the mouse embryo

(2008) C. He et al.   DEVELOPMENT

Identification of erythroid-enriched gene expression in the mouse embryonic yolk sac using microdissected cells

(2008) Latasha C. Redmond et al.   DEVELOPMENTAL DYNAMICS

Myc's broad reach

(2008) M. Eilers et al.   GENES & DEVELOPMENT

Evidence for a Bigenic Chromatin Subdomain in Regulation of the Fetal-to-Adult Hemoglobin Switch

(2008) H. Beauchemin et al.   MOLECULAR AND CELLULAR BIOLOGY

Failure of Terminal Erythroid Differentiation in EKLF-Deficient Mice Is Associated with Cell Cycle Perturbation and Reduced Expression of E2F2

(2008) A. M. Pilon et al.   MOLECULAR AND CELLULAR BIOLOGY

Myc Inhibits p27-Induced Erythroid Differentiation of Leukemia Cells by Repressing Erythroid Master Genes without Reversing p27-Mediated Cell Cycle Arrest

(2008) J. C. Acosta et al.   MOLECULAR AND CELLULAR BIOLOGY

A core Klf circuitry regulates self-renewal of embryonic stem cells

(2008) Jianming Jiang et al.   NATURE CELL BIOLOGY