DLX4is associated with orofacial clefting and abnormal jaw development

HeterozygousDLX5nonsense mutation associated with isolated split-hand/foot malformation with reduced penetrance and variable expressivity in two unrelated families

(2014) Anna Sowińska-Seidler et al.   BIRTH DEFECTS RESEARCH PART A-CLINICAL AND MOLECULAR TERATOLOGY

Exome sequencing reveals a heterozygous DLX5 mutation in a Chinese family with autosomal-dominant split-hand/foot malformation

(2014) Xue Wang et al.   EUROPEAN JOURNAL OF HUMAN GENETICS

Genetics of cleft lip and/or cleft palate: Association with other common anomalies

(2014) Núria Setó-Salvia et al.   European Journal of Medical Genetics

A LINE-1 Insertion in DLX6 Is Responsible for Cleft Palate and Mandibular Abnormalities in a Canine Model of Pierre Robin Sequence

(2014) Zena T. Wolf et al.   PLoS Genetics

Genetics of cleft lip and cleft palate

(2013) Elizabeth J. Leslie et al.   AMERICAN JOURNAL OF MEDICAL GENETICS PART C-SEMINARS IN MEDICAL GENETICS

Pdgfra protects against ethanol-induced craniofacial defects in a zebrafish model of FASD

(2013) N. McCarthy et al.   DEVELOPMENT

ALDH1A3 loss of function causes bilateral anophthalmia/microphthalmia and hypoplasia of the optic nerve and optic chiasm

(2013) Mani Yahyavi et al.   HUMAN MOLECULAR GENETICS

Association between MSX1 SNPs and Nonsyndromic Cleft Lip with or without Cleft Palate in the Korean Population

(2013) Na Young Kim et al.   JOURNAL OF KOREAN MEDICAL SCIENCE

Distinct requirements for wnt9a and irf6 in extension and integration mechanisms during zebrafish palate morphogenesis

(2012) M. Dougherty et al.   DEVELOPMENT

Bmp signaling regulates a dose-dependent transcriptional program to control facial skeletal development

(2012) M. Bonilla-Claudio et al.   DEVELOPMENT

Cleft palate defect ofDlx1/2−/− mutant mice is caused by lack of vertical outgrowth in the posterior palate

(2012) Juhee Jeong et al.   DEVELOPMENTAL DYNAMICS

Craniofacial abnormalities result from knock down of nonsyndromic clefting gene,crispld2, in zebrafish

(2012) Qiuping Yuan et al.   GENESIS

Focal facial dermal dysplasia, type IV, is caused by mutations in CYP26C1

(2012) A. M. Slavotinek et al.   HUMAN MOLECULAR GENETICS

BP1, an Isoform of DLX4 Homeoprotein, Negatively Regulates BRCA1 in Sporadic Breast Cancer

(2012) Brian J. Kluk et al.   International Journal of Biological Sciences

DLX4 Upregulates TWIST and Enhances Tumor Migration, Invasion and Metastasis

(2012) Lianmei Zhang et al.   International Journal of Biological Sciences

wANNOVAR: annotating genetic variants for personal genomes via the web

(2012) Xiao Chang et al.   JOURNAL OF MEDICAL GENETICS

BMP4 Was Associated with NSCL/P in an Asian Population

(2012) Qianqian Chen et al.   PLoS One

DLX3 Homeodomain Mutations Cause Tricho-Dento-Osseous Syndrome with Novel Phenotypes

(2011) Pekka Nieminen et al.   CELLS TISSUES ORGANS

Genetics of Nonsyndromic Orofacial Clefts

(2011) Fedik Rahimov et al.   CLEFT PALATE-CRANIOFACIAL JOURNAL

Demographics of Orofacial Clefts in Canada from 2002 to 2008

(2011) Sabrina Pavri et al.   CLEFT PALATE-CRANIOFACIAL JOURNAL

Examination of a palatogenic gene program in zebrafish

(2011) Mary E. Swartz et al.   DEVELOPMENTAL DYNAMICS

Identification of a novelDLX5mutation in a family with autosomal recessive split hand and foot malformation

(2011) Hanan E Shamseldin et al.   JOURNAL OF MEDICAL GENETICS

Homeodomain protein DLX4 counteracts key transcriptional control mechanisms of the TGF-β cytostatic program and blocks the antiproliferative effect of TGF-β

(2011) B Q Trinh et al.   ONCOGENE

Imperforate anus is a rare associated finding in blepharocheilodontic syndrome

(2010) K. Nicole Weaver et al.   AMERICAN JOURNAL OF MEDICAL GENETICS PART A

Prevalence at Birth of Cleft Lip with or without Cleft Palate: Data from the International Perinatal Database of Typical Oral Clefts (IPDTOC)

(2010)   CLEFT PALATE-CRANIOFACIAL JOURNAL

hand2 and Dlx genes specify dorsal, intermediate and ventral domains within zebrafish pharyngeal arches

(2010) J. C. Talbot et al.   DEVELOPMENT

Modulation of BMP signaling by Noggin is required for the maintenance of palatal epithelial integrity during palatogenesis

(2010) Fenglei He et al.   DEVELOPMENTAL BIOLOGY

MutationTaster evaluates disease-causing potential of sequence alterations

(2010) Jana Marie Schwarz et al.   NATURE METHODS

ANNOVAR: functional annotation of genetic variants from high-throughput sequencing data

(2010) K. Wang et al.   NUCLEIC ACIDS RESEARCH

Mutations in BMP4 Are Associated with Subepithelial, Microform, and Overt Cleft Lip

(2009) Satoshi Suzuki et al.   AMERICAN JOURNAL OF HUMAN GENETICS

The Frequency of Palatal Anomalies in Saethre-Chotzen Syndrome

(2009) Joan M. Stoler et al.   CLEFT PALATE-CRANIOFACIAL JOURNAL

Amplification of the BP1 homeobox gene in breast cancer

(2008) Luciane R. Cavalli et al.   CANCER GENETICS AND CYTOGENETICS

Characterization of a distinct subpopulation of striatal projection neurons expressing the Dlx genes in the basal ganglia through the activity of the I56ii enhancer

(2008) Noël Ghanem et al.   DEVELOPMENTAL BIOLOGY

dlx3b/4b are required for the formation of the preplacodal region and otic placode through local modulation of BMP activity

(2008) Robert Esterberg et al.   DEVELOPMENTAL BIOLOGY

Candidate gene/loci studies in cleft lip/palate and dental anomalies finds novel susceptibility genes for clefts

(2008) Alexandre R Vieira et al.   GENETICS IN MEDICINE

BP1, a homeoprotein, is significantly expressed in prostate adenocarcinoma and is concordant with prostatic intraepithelial neoplasia

(2008) Arnold M Schwartz et al.   MODERN PATHOLOGY

Zebrafish dlx2a contributes to hindbrain neural crest survival, is necessary for differentiation of sensory ganglia and functions with dlx1a in maturation of the arch cartilage elements

(2007) Steven M. Sperber et al.   DEVELOPMENTAL BIOLOGY