Gene-based meta-analysis of genome-wide association studies implicates new loci involved in obesity

Structure, production and signaling of leptin

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Genetic studies of body mass index yield new insights for obesity biology

(2015) Adam E. Locke et al.   NATURE

FTO Obesity Variant Circuitry and Adipocyte Browning in Humans

(2015) Melina Claussnitzer et al.   NEW ENGLAND JOURNAL OF MEDICINE

FTO influences adipogenesis by regulating mitotic clonal expansion

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MethylAid: visual and interactive quality control of large Illumina 450k datasets

(2014) M. van Iterson et al.   BIOINFORMATICS

GRASP: analysis of genotype-phenotype results from 1390 genome-wide association studies and corresponding open access database

(2014) R. Leslie et al.   BIOINFORMATICS

Hypomorphism for RPGRIP1L, a Ciliary Gene Vicinal to the FTO Locus, Causes Increased Adiposity in Mice

(2014) George Stratigopoulos et al.   Cell Metabolism

Obesity-associated variants within FTO form long-range functional connections with IRX3

(2014) Scott Smemo et al.   NATURE

Global Analysis of DNA Methylation Variation in Adipose Tissue from Twins Reveals Links to Disease-Associated Variants in Distal Regulatory Elements

(2013) Elin Grundberg et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Zfyve9a regulates the proliferation of hepatic cells during zebrafish embryogenesis

(2013) Nian Liu et al.   INTERNATIONAL JOURNAL OF DEVELOPMENTAL BIOLOGY

The Genotype-Tissue Expression (GTEx) project

(2013) John Lonsdale et al.   NATURE GENETICS

Recent Adaptive Events in Human Brain Revealed by Meta-Analysis of Positively Selected Genes

(2013) Yue Huang et al.   PLoS One

Assessing Methods for Assigning SNPs to Genes in Gene-Based Tests of Association Using Common Variants

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A Multi-SNP Locus-Association Method Reveals a Substantial Fraction of the Missing Heritability

(2012) Georg B. Ehret et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Isolation and characterization of a thioredoxin domain-containing protein 12 from orange-spotted grouper, Epinephelus coioides

(2012) Jingguang Wei et al.   FISH & SHELLFISH IMMUNOLOGY

Mapping cis- and trans-regulatory effects across multiple tissues in twins

(2012) Elin Grundberg et al.   NATURE GENETICS

The ConsensusPathDB interaction database: 2013 update

(2012) Atanas Kamburov et al.   NUCLEIC ACIDS RESEARCH

Gene Size Matters

(2012) Alexandra Mirina et al.   PLoS One

GATES: A Rapid and Powerful Gene-Based Association Test Using Extended Simes Procedure

(2011) Miao-Xin Li et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Evaluation of an approximation method for assessment of overall significance of multiple-dependent tests in a genomewide association study

(2011) Valentina Moskvina et al.   GENETIC EPIDEMIOLOGY

Isoleucyl-tRNA synthetase levels modulate the penetrance of a homoplasmic m.4277T>C mitochondrial tRNAIle mutation causing hypertrophic cardiomyopathy

(2011) Elena Perli et al.   HUMAN MOLECULAR GENETICS

Allelic heterogeneity and more detailed analyses of known loci explain additional phenotypic variation and reveal complex patterns of association

(2011) Andrew R. Wood et al.   HUMAN MOLECULAR GENETICS

Elevation of hemopexin-like fragment of matrix metalloproteinase-2 tissue levels inhibits ischemic wound healing and angiogenesis

(2011) April E. Nedeau et al.   JOURNAL OF VASCULAR SURGERY

Gene-Based Tests of Association

(2011) Hailiang Huang et al.   PLoS Genetics

A Versatile Gene-Based Test for Genome-wide Association Studies

(2010) Jimmy Z. Liu et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Genevar: a database and Java application for the analysis and visualization of SNP-gene associations in eQTL studies

(2010) T.-P. Yang et al.   BIOINFORMATICS

Centriolar Association of ALMS1 and Likely Centrosomal Functions of the ALMS Motif–containing Proteins C10orf90 and KIAA1731

(2010) Victoria J. Knorz et al.   MOLECULAR BIOLOGY OF THE CELL

Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index

(2010) Elizabeth K Speliotes et al.   NATURE GENETICS

Pancreatic Hypertrophy in Ki-ras-Induced Actin-Interacting Protein Gene Knockout Mice

(2010) Kyoko Miyasaka et al.   PANCREAS

Strategies and issues in the detection of pathway enrichment in genome-wide association studies

(2009) Mun-Gwan Hong et al.   HUMAN GENETICS

Finding the missing heritability of complex diseases

(2009) Teri A. Manolio et al.   NATURE

Altered Energy Homeostasis and Resistance to Diet-Induced Obesity in KRAP-Deficient Mice

(2009) Takahiro Fujimoto et al.   PLoS One