Integration of multiethnic fine-mapping and genomic annotation to prioritize candidate functional SNPs at prostate cancer susceptibility regions

Fine mapping of type 1 diabetes susceptibility loci and evidence for colocalization of causal variants with lymphoid gene enhancers

(2015) Suna Onengut-Gumuscu et al.   NATURE GENETICS

Joint Analysis of Functional Genomic Data and Genome-wide Association Studies of 18 Human Traits

(2014) Joseph K. Pickrell   AMERICAN JOURNAL OF HUMAN GENETICS

From genome to function by studying eQTLs

(2014) Harm-Jan Westra et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Nucleosome positioning and histone modifications define relationships between regulatory elements and nearby gene expression in breast epithelial cells

(2014) Suhn Rhie et al.   BMC GENOMICS

CtBP2 Modulates the Androgen Receptor to Promote Prostate Cancer Progression

(2014) K.-i. Takayama et al.   CANCER RESEARCH

Expression QTL-based analyses reveal candidate causal genes and loci across five tumor types

(2014) Qiyuan Li et al.   HUMAN MOLECULAR GENETICS

Multi-ethnic fine-mapping of 14 central adiposity loci

(2014) C.-T. Liu et al.   HUMAN MOLECULAR GENETICS

A meta-analysis of 87,040 individuals identifies 23 new susceptibility loci for prostate cancer

(2014) Ali Amin Al Olama et al.   NATURE GENETICS

A prostate cancer susceptibility allele at 6q22 increases RFX6 expression by modulating HOXB13 chromatin binding

(2014) Qilai Huang et al.   NATURE GENETICS

Genome-wide trans-ancestry meta-analysis provides insight into the genetic architecture of type 2 diabetes susceptibility

(2014) Anubha Mahajan et al.   NATURE GENETICS

Comprehensive Functional Annotation of 77 Prostate Cancer Risk Loci

(2014) Dennis J. Hazelett et al.   PLoS Genetics

Integrative eQTL-Based Analyses Reveal the Biology of Breast Cancer Risk Loci

(2013) Qiyuan Li et al.   CELL

Variants at IRX4 as prostate cancer expression quantitative trait loci

(2013) Xing Xu et al.   EUROPEAN JOURNAL OF HUMAN GENETICS

A genome-wide association study of prostate cancer in West African men

(2013) Michael Blaise Cook et al.   HUMAN GENETICS

Fine-mapping identifies multiple prostate cancer risk loci at 5p15, one of which associates with TERT expression

(2013) Zsofia Kote-Jarai et al.   HUMAN MOLECULAR GENETICS

Identification of 23 new prostate cancer susceptibility loci using the iCOGS custom genotyping array

(2013) Rosalind A Eeles et al.   NATURE GENETICS

Chromatin stretch enhancer states drive cell-specific gene regulation and harbor human disease risk variants

(2013) S. C. J. Parker et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Trans-Ethnic Fine-Mapping of Lipid Loci Identifies Population-Specific Signals and Allelic Heterogeneity That Increases the Trait Variance Explained

(2013) Ying Wu et al.   PLoS Genetics

Discovery and Fine Mapping of Serum Protein Loci through Transethnic Meta-analysis

(2012) Nora Franceschini et al.   AMERICAN JOURNAL OF HUMAN GENETICS

miRcode: a map of putative microRNA target sites in the long non-coding transcriptome

(2012) Ashwini Jeggari et al.   BIOINFORMATICS

The Androgen Receptor Induces a Distinct Transcriptional Program in Castration-Resistant Prostate Cancer in Man

(2012) Naomi L. Sharma et al.   CANCER CELL

Evaluating Genetic Risk for Prostate Cancer among Japanese and Latinos

(2012) I. Cheng et al.   CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION

Efficiency of trans-ethnic genome-wide meta-analysis and fine-mapping

(2012) Rick Twee-Hee Ong et al.   EUROPEAN JOURNAL OF HUMAN GENETICS

Annotation of functional variation in personal genomes using RegulomeDB

(2012) A. P. Boyle et al.   GENOME RESEARCH

The accessible chromatin landscape of the human genome

(2012) Robert E. Thurman et al.   NATURE

Common variants at 11q12, 10q26 and 3p11.2 are associated with prostate cancer susceptibility in Japanese

(2012) Shusuke Akamatsu et al.   NATURE GENETICS

Bayesian refinement of association signals for 14 loci in 3 common diseases

(2012) Julian B Maller et al.   NATURE GENETICS

Genome-wide association study in Chinese men identifies two new prostate cancer risk loci at 9q31.2 and 19q13.4

(2012) Jianfeng Xu et al.   NATURE GENETICS

FunciSNP: an R/bioconductor tool integrating functional non-coding data sets with genetic association studies to identify candidate regulatory SNPs

(2012) Simon G. Coetzee et al.   NUCLEIC ACIDS RESEARCH

Genetic and functional analyses implicate the NUDT11, HNF1B, and SLC22A3 genes in prostate cancer pathogenesis

(2012) C. Grisanzio et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Systematic Localization of Common Disease-Associated Variation in Regulatory DNA

(2012) M. T. Maurano et al.   SCIENCE

Prostate cancer epidemiology in the United States

(2012) Otis W. Brawley   WORLD JOURNAL OF UROLOGY

Transethnic meta-analysis of genomewide association studies

(2011) Andrew P. Morris   GENETIC EPIDEMIOLOGY

Fine mapping the KLK3 locus on chromosome 19q13.33 associated with prostate cancer susceptibility and PSA levels

(2011) Hemang Parikh et al.   HUMAN GENETICS

Identification of a novel prostate cancer susceptibility variant in the KLK3 gene transcript

(2011) Z. Kote-Jarai et al.   HUMAN GENETICS

Large-scale fine mapping of the HNF1B locus and prostate cancer risk

(2011) Sonja I. Berndt et al.   HUMAN MOLECULAR GENETICS

Fine mapping of a region of chromosome 11q13 reveals multiple independent loci associated with risk of prostate cancer

(2011) Charles C. Chung et al.   HUMAN MOLECULAR GENETICS

Genome-wide association study identifies new prostate cancer susceptibility loci

(2011) Fredrick R. Schumacher et al.   HUMAN MOLECULAR GENETICS

Integration of Regulatory Networks by NKX3-1 Promotes Androgen-Dependent Prostate Cancer Survival

(2011) P. Y. Tan et al.   MOLECULAR AND CELLULAR BIOLOGY

Dynamic Nucleosome-Depleted Regions at Androgen Receptor Enhancers in the Absence of Ligand in Prostate Cancer Cells

(2011) C. Andreu-Vieyra et al.   MOLECULAR AND CELLULAR BIOLOGY

Reprogramming transcription by distinct classes of enhancers functionally defined by eRNA

(2011) Dong Wang et al.   NATURE

Genome-wide association study of prostate cancer in men of African ancestry identifies a susceptibility locus at 17q21

(2011) Christopher A Haiman et al.   NATURE GENETICS

Seven prostate cancer susceptibility loci identified by a multi-stage genome-wide association study

(2011) Zsofia Kote-Jarai et al.   NATURE GENETICS

HaploReg: a resource for exploring chromatin states, conservation, and regulatory motif alterations within sets of genetically linked variants

(2011) L. D. Ward et al.   NUCLEIC ACIDS RESEARCH

Comprehensive resequence analysis of a 123-kb region of chromosome 11q13 associated with prostate cancer

(2011) Charles C. Chung et al.   PROSTATE

Characterizing Genetic Risk at Known Prostate Cancer Susceptibility Loci in African Americans

(2011) Christopher A. Haiman et al.   PLoS Genetics

Leveraging Genetic Variability across Populations for the Identification of Causal Variants

(2010) Noah Zaitlen et al.   AMERICAN JOURNAL OF HUMAN GENETICS

A systematic approach to understand the functional consequences of non-protein coding risk regions

(2010) Gerhard A. Coetzee et al.   CELL CYCLE

Identifying candidate causal variants via trans-population fine-mapping

(2010) Yik-Ying Teo et al.   GENETIC EPIDEMIOLOGY

A functional variant in NKX3.1 associated with prostate cancer susceptibility down-regulates NKX3.1 expression

(2010) Shusuke Akamatsu et al.   HUMAN MOLECULAR GENETICS

Genome-wide association study identifies five new susceptibility loci for prostate cancer in the Japanese population

(2010) Ryo Takata et al.   NATURE GENETICS

8q24 prostate, breast, and colon cancer risk loci show tissue-specific long-range interaction with MYC

(2010) N. Ahmadiyeh et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Analysis of the 10q11 Cancer Risk Locus Implicates MSMB and NCOA4 in Human Prostate Tumorigenesis

(2010) Mark M. Pomerantz et al.   PLoS Genetics

Trait-Associated SNPs Are More Likely to Be eQTLs: Annotation to Enhance Discovery from GWAS

(2010) Dan L. Nicolae et al.   PLoS Genetics

Two Independent Prostate Cancer Risk-Associated Loci at 11q13

(2009) S. L. Zheng et al.   CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION

Identification of seven new prostate cancer susceptibility loci through a genome-wide association study

(2009) Rosalind A Eeles et al.   NATURE GENETICS

Identification of a new prostate cancer susceptibility locus on chromosome 8q24

(2009) Meredith Yeager et al.   NATURE GENETICS

Genome-wide association and replication studies identify four variants associated with prostate cancer susceptibility

(2009) Julius Gudmundsson et al.   NATURE GENETICS

Multiple loci on 8q24 associated with prostate cancer susceptibility

(2009) Ali Amin Al Olama et al.   NATURE GENETICS

Mapping complex disease traits with global gene expression

(2009) William Cookson et al.   NATURE REVIEWS GENETICS

Fine mapping and functional analysis of a common variant in MSMB on chromosome 10q11.2 associated with prostate cancer susceptibility

(2009) H. Lou et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Functional Enhancers at the Gene-Poor 8q24 Cancer-Linked Locus

(2009) Li Jia et al.   PLoS Genetics

A Flexible and Accurate Genotype Imputation Method for the Next Generation of Genome-Wide Association Studies

(2009) Bryan N. Howie et al.   PLoS Genetics

Multiple Novel Prostate Cancer Predisposition Loci Confirmed by an International Study: The PRACTICAL Consortium

(2008) Z. Kote-Jarai et al.   CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION

Sequence Variants at 22q13 Are Associated with Prostate Cancer Risk

(2008) J. Sun et al.   CANCER RESEARCH

Bayes factors for genome-wide association studies: comparison withP-values

(2008) Jon Wakefield   GENETIC EPIDEMIOLOGY

Evidence for two independent prostate cancer risk–associated loci in the HNF1B gene at 17q12

(2008) Jielin Sun et al.   NATURE GENETICS

Common sequence variants on 2p15 and Xp11.22 confer susceptibility to prostate cancer

(2008) Julius Gudmundsson et al.   NATURE GENETICS

Multiple newly identified loci associated with prostate cancer susceptibility

(2008) Rosalind A Eeles et al.   NATURE GENETICS