Breast cancer metastasis to liver and lung is facilitated by Pit-1-CXCL12-CXCR4 axis

Inhibition of signaling between human CXCR4 and zebrafish ligands by the small molecule IT1t impairs the formation of triple-negative breast cancer early metastases in a zebrafish xenograft model

(2016) Claudia Tulotta et al.   Disease Models & Mechanisms

CXCR4 inhibitors could benefit to HER2 but not to triple-negative breast cancer patients

(2016) S Lefort et al.   ONCOGENE

Over-Expression of POU Class 1 Homeobox 1 Transcription Factor (Pit-1) Predicts Poor Prognosis for Breast Cancer Patients

(2016) Zhongcheng Gao et al.   MEDICAL SCIENCE MONITOR

Molecular Pathways: Targeting the CXCR4-CXCL12 Axis--Untapped Potential in the Tumor Microenvironment

(2015) S. Scala   CLINICAL CANCER RESEARCH

CXCL12/CXCR4: a symbiotic bridge linking cancer cells and their stromal neighbors in oncogenic communication networks

(2015) F Guo et al.   ONCOGENE

A phenotype from tumor stroma based on the expression of metalloproteases and their inhibitors, associated with prognosis in breast cancer

(2015) Noemí Eiró et al.   OncoImmunology

Targeting CXCL12/CXCR4 signaling with oncolytic virotherapy disrupts tumor vasculature and inhibits breast cancer metastases

(2013) M. Gil et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A review on CXCR4/CXCL12 axis in oncology: No place to hide

(2012) Urszula M. Domanska et al.   EUROPEAN JOURNAL OF CANCER

Tumor Metastasis: Molecular Insights and Evolving Paradigms

(2011) Scott Valastyan et al.   CELL

A Computational Tool for Quantitative Analysis of Vascular Networks

(2011) Enrique Zudaire et al.   PLoS One

CXCR4 peptide antagonist inhibits primary breast tumor growth, metastasis and enhances the efficacy of anti-VEGF treatment or docetaxel in a transgenic mouse model

(2010) Saima Hassan et al.   INTERNATIONAL JOURNAL OF CANCER

Deregulation of the Pit-1 transcription factor in human breast cancer cells promotes tumor growth and metastasis

(2010) Isabel Ben-Batalla et al.   JOURNAL OF CLINICAL INVESTIGATION

Chemokines and chemokine receptors: new insights into cancer-related inflammation

(2010) Gwendal Lazennec et al.   TRENDS IN MOLECULAR MEDICINE

An online survival analysis tool to rapidly assess the effect of 22,277 genes on breast cancer prognosis using microarray data of 1,809 patients

(2009) Balazs Györffy et al.   BREAST CANCER RESEARCH AND TREATMENT

Cxcl12a–Cxcr4b signaling is important for proper development of the forebrain GnRH system in zebrafish

(2009) Ori Palevitch et al.   GENERAL AND COMPARATIVE ENDOCRINOLOGY

CXCL12/CXCR4 signalling in neuronal cell migration

(2008) Marie-Catherine Tiveron et al.   CURRENT OPINION IN NEUROBIOLOGY

A CXCR4 Antagonist CTCE-9908 Inhibits Primary Tumor Growth and Metastasis of Breast Cancer

(2008) Eugene H. Huang et al.   JOURNAL OF SURGICAL RESEARCH

Direct inhibition of the DNA-binding activity of POU transcription factors Pit-1 and Brn-3 by selective binding of a phenyl-furan-benzimidazole dication

(2008) Paul Peixoto et al.   NUCLEIC ACIDS RESEARCH