A genome-wide expression quantitative trait loci analysis of proprotein convertase subtilisin/kexin enzymes identifies a novel regulatory gene variant for FURIN expression and blood pressure
Published 2015 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
A genome-wide expression quantitative trait loci analysis of proprotein convertase subtilisin/kexin enzymes identifies a novel regulatory gene variant for FURIN expression and blood pressure
Authors
Keywords
Lactase Persistence, eQTL Analysis, PCSK Gene, Young Finn Study, PCSK Expression
Journal
HUMAN GENETICS
Volume 134, Issue 6, Pages 627-636
Publisher
Springer Nature
Online
2015-03-27
DOI
10.1007/s00439-015-1546-5
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- From genome to function by studying eQTLs
- (2014) Harm-Jan Westra et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE
- Cardiovascular risk factors in 2011 and secular trends since 2007: The Cardiovascular Risk in Young Finns Study
- (2014) Joel Nuotio et al. SCANDINAVIAN JOURNAL OF PUBLIC HEALTH
- Mapping eQTLs in the Norfolk Island Genetic Isolate Identifies Candidate Genes for CVD Risk Traits
- (2013) Miles C. Benton et al. AMERICAN JOURNAL OF HUMAN GENETICS
- Association of resting heart rate with cardiovascular function: a cross-sectional study in 522 Finnish subjects
- (2013) Jenni K Koskela et al. BMC Cardiovascular Disorders
- Association of Neuroimmune Guidance Cue Netrin-1 and Its Chemorepulsive Receptor UNC5B With Atherosclerotic Plaque Expression Signatures and Stability in Human(s)
- (2013) Niku Oksala et al. Circulation-Cardiovascular Genetics
- Genetics of the First Seven Proprotein Convertase Enzymes in Health and Disease
- (2013) Hannu Turpeinen et al. CURRENT GENOMICS
- Loci influencing blood pressure identified using a cardiovascular gene-centric array
- (2013) Santhi K. Ganesh, Vinicius Tragante, Wei Guo, Yiran Guo, Matthew B. Lanktree, Erin N. Smith, Toby Johnson, Berta Almoguera Castillo, John Barnard, Jens Baumert, Yen-Pei Christy Chang, Clara C. Elbers, Martin Farrall, Mary E. Fischer, Nora Franceschini, Tom R. Gaunt, Johannes M.I.H. Gho, Christian Gieger, Yan Gong, Aaron Isaacs, Marcus E. Kleber, Irene Mateo Leach, Caitrin W. McDonough, Matthijs F.L. Meijs, Olle Mellander, Cliona M. Molony, Ilja M. Nolte, Sandosh Padmanabhan, Tom S. Price, Ramakrishnan Rajagopalan, Jonathan Shaffer, Sonia Shah, Haiqing Shen, Nicole Soranzo, Peter J. van der Most, Erik P.A. Van Iperen, Jessic A. Van Setten, Judith M. Vonk, Li Zhang, Amber L. Beitelshees, Gerald S. Berenson, Deepak L. Bhatt, Jolanda M.A. Boer, Eric Boerwinkle, Ben Burkley, Amber Burt, Aravinda Chakravarti, Wei Chen, Rhonda M. Cooper-DeHoff, Sean P. Curtis, Albert Dreisbach, David Duggan, Georg B. Ehret, Richard R. Fabsitz, Myriam Fornage, Ervin Fox, Clement E. Furlong, Ron T. Gansevoort, Marten H. Hofker, G. Kees Hovingh, Susan A. Kirkland, Kandice Kottke-Marchant, Abdullah Kutlar, Andrea Z. LaCroix, Taimour Y. Langaee, Yun R. Li, Honghuang Lin, Kiang Liu, Steffi Maiwald, Rainer Malik, Gurunathan Murugesan, Christopher Newton-Cheh, Jeffery R. O'Connell, N. Charlotte Onland-Moret, Willem H. Ouwehand et al. HUMAN MOLECULAR GENETICS
- An Update on Immune System Activation in the Pathogenesis of Hypertension
- (2013) Michael J. Ryan HYPERTENSION
- The Multifaceted Proprotein Convertases: Their Unique, Redundant, Complementary, and Opposite Functions
- (2013) Nabil G. Seidah et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Systematic identification of trans eQTLs as putative drivers of known disease associations
- (2013) Harm-Jan Westra et al. NATURE GENETICS
- Alzheimer's disease susceptibility variants in the MS4A6A gene are associated with altered levels of MS4A6A expression in blood
- (2013) Petroula Proitsi et al. NEUROBIOLOGY OF AGING
- Proprotein Convertase Subtilisin/Kexin Type 3 Promotes Adipose Tissue-Driven Macrophage Chemotaxis and Is Increased in Obesity
- (2013) Kai Kappert et al. PLoS One
- Fast and accurate genotype imputation in genome-wide association studies through pre-phasing
- (2012) Bryan Howie et al. NATURE GENETICS
- The biology and therapeutic targeting of the proprotein convertases
- (2012) Nabil G. Seidah et al. NATURE REVIEWS DRUG DISCOVERY
- Proprotein convertases in human atherosclerotic plaques: The overexpression of FURIN and its substrate cytokines BAFF and APRIL
- (2011) Hannu Turpeinen et al. ATHEROSCLEROSIS
- Identification of proprotein convertase substrates using genome-wide expression correlation analysis
- (2011) Hannu Turpeinen et al. BMC GENOMICS
- Genetic variants in novel pathways influence blood pressure and cardiovascular disease risk
- (2011) Georg B. Ehret et al. NATURE
- Proprotein Convertases in Health and Disease
- (2011) Andrew W. Artenstein et al. NEW ENGLAND JOURNAL OF MEDICINE
- LocusZoom: regional visualization of genome-wide association scan results
- (2010) R. J. Pruim et al. BIOINFORMATICS
- Associations between genetic variations in the FURIN gene and hypertension
- (2010) Nanfang Li et al. BMC Medical Genetics
- Processing of Pro-B-Type Natriuretic Peptide: Furin and Corin as Candidate Convertases
- (2010) A. G. Semenov et al. CLINICAL CHEMISTRY
- Multiple common variants for celiac disease influencing immune gene expression
- (2010) Patrick C A Dubois et al. NATURE GENETICS
- Zebrafish ProVEGF-C Expression, Proteolytic Processing and Inhibitory Effect of Unprocessed ProVEGF-C during Fin Regeneration
- (2010) Abdel-Majid Khatib et al. PLoS One
- ADAM-9, ADAM-15, and ADAM-17 are upregulated in macrophages in advanced human atherosclerotic plaques in aorta and carotid and femoral arteries—Tampere vascular study
- (2009) Niku Oksala et al. ANNALS OF MEDICINE
- Influence of a single nucleotide polymorphism in the P1 promoter of the furin gene on transcription activity and hepatitis B virus infection
- (2009) Rui Xiang Lei et al. HEPATOLOGY
- Soluble Form of the (Pro)Renin Receptor Generated by Intracellular Cleavage by Furin Is Secreted in Plasma
- (2009) Christelle Cousin et al. HYPERTENSION
- Genome-wide association study identifies eight loci associated with blood pressure
- (2009) Christopher Newton-Cheh et al. NATURE GENETICS
- Prorenin and (pro)renin receptor: a review of available data fromin vitrostudies and experimental models in rodents
- (2008) Geneviève Nguyen et al. EXPERIMENTAL PHYSIOLOGY
- Lactose digestion and the evolutionary genetics of lactase persistence
- (2008) Catherine J. E. Ingram et al. HUMAN GENETICS
- The activation and physiological functions of the proprotein convertases
- (2008) N SEIDAH et al. INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY
- Global burden of blood-pressure-related disease, 2001
- (2008) Carlene MM Lawes et al. LANCET
- Analysis of cardiovascular responses to passive head‐up tilt using continuous pulse wave analysis and impedance cardiography
- (2008) Anna Tahvanainen et al. SCANDINAVIAN JOURNAL OF CLINICAL & LABORATORY INVESTIGATION
- The Cell-Specific Pattern of Cholecystokinin Peptides in Endocrine CellsVersusNeurons Is Governed by the Expression of Prohormone Convertases 1/3, 2, and 5/6
- (2007) Jens F. Rehfeld et al. ENDOCRINOLOGY
Discover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversationPublish scientific posters with Peeref
Peeref publishes scientific posters from all research disciplines. Our Diamond Open Access policy means free access to content and no publication fees for authors.
Learn More