Oxidative stress increases M1dG, a major peroxidation-derived DNA adduct, in mitochondrial DNA

BMPR2 Preserves Mitochondrial Function and DNA during Reoxygenation to Promote Endothelial Cell Survival and Reverse Pulmonary Hypertension

(2015) Isabel Diebold et al.   Cell Metabolism

Nuclear Oxidation of a Major Peroxidation DNA Adduct, M1dG, in the Genome

(2015) Orrette R. Wauchope et al.   CHEMICAL RESEARCH IN TOXICOLOGY

Estrogen Metabolite 16α-Hydroxyestrone Exacerbates Bone Morphogenetic Protein Receptor Type II–Associated Pulmonary Arterial Hypertension Through MicroRNA-29–Mediated Modulation of Cellular MetabolismCLINICAL PERSPECTIVE

(2015) Xinping Chen et al.   CIRCULATION

Electron flow into cytochrome c coupled with reactive oxygen species from the electron transport chain converts cytochrome c to a cardiolipin peroxidase: role during ischemia–reperfusion

(2014) Hema S. Aluri et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Analysis of a Malondialdehyde–Deoxyguanosine Adduct in Human Leukocyte DNA by Liquid Chromatography Nanoelectrospray–High-Resolution Tandem Mass Spectrometry

(2014) Bin Ma et al.   CHEMICAL RESEARCH IN TOXICOLOGY

Pulmonary Arterial Hypertension

(2014) Yen-Chun Lai et al.   CIRCULATION RESEARCH

Heterozygous Null Bone Morphogenetic Protein Receptor Type 2 Mutations Promote SRC Kinase-dependent Caveolar Trafficking Defects and Endothelial Dysfunction in Pulmonary Arterial Hypertension

(2014) Allison R. Prewitt et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Oxidative Injury is a Common Consequence of BMPR2 Mutations

(2014) Kirk L. Lane et al.   Pulmonary Circulation

Interaction between Bone Morphogenetic Protein Receptor Type 2 and Estrogenic Compounds in Pulmonary Arterial Hypertension

(2014) Joshua P. Fessel et al.   Pulmonary Circulation

Interaction of Sirt3 with OGG1 contributes to repair of mitochondrial DNA and protects from apoptotic cell death under oxidative stress

(2013) Y Cheng et al.   Cell Death & Disease

Selection of Monoclonal Antibodies Against 6-oxo-M1dG and Their Use in an LC-MS/MS Assay for the Presence of 6-oxo-M1dG in Vivo

(2012) Dapo Akingbade et al.   CHEMICAL RESEARCH IN TOXICOLOGY

Mitochondrial DNA nucleoid structure

(2011) Daniel F. Bogenhagen   Biochimica et Biophysica Acta-Gene Regulatory Mechanisms

Cross talk between mitochondria and NADPH oxidases

(2011) Sergey Dikalov   FREE RADICAL BIOLOGY AND MEDICINE

Repair of persistent strand breaks in the mitochondrial genome

(2011) Peter Sykora et al.   MECHANISMS OF AGEING AND DEVELOPMENT

Therapeutic Targeting of Mitochondrial Superoxide in Hypertension

(2010) Anna E. Dikalova et al.   CIRCULATION RESEARCH

A Mouse Macrophage Lipidome

(2010) Edward A. Dennis et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Arrest of human mitochondrial RNA polymerase transcription by the biological aldehyde adduct of DNA, M 1 dG

(2010) Susan D. Cline et al.   NUCLEIC ACIDS RESEARCH

Oxidative stress induces degradation of mitochondrial DNA

(2009) Inna Shokolenko et al.   NUCLEIC ACIDS RESEARCH

NF- B as a Critical Link Between Inflammation and Cancer

(2009) M. Karin   Cold Spring Harbor Perspectives in Biology

Mitochondrial base excision repair of uracil and AP sites takes place by single-nucleotide insertion and long-patch DNA synthesis

(2008) Mansour Akbari et al.   DNA REPAIR

Accumulation of M1dG DNA adducts after chronic exposure to PCBs, but not from acute exposure to polychlorinated aromatic hydrocarbons

(2008) Yo-Chan Jeong et al.   FREE RADICAL BIOLOGY AND MEDICINE

Removal of Oxidative DNA Damage via FEN1-Dependent Long-Patch Base Excision Repair in Human Cell Mitochondria

(2008) P. Liu et al.   MOLECULAR AND CELLULAR BIOLOGY

Effect of vitamin levels on biomarkers of exposure and oxidative damage—The EXPAH study

(2008) R.J. Sram et al.   MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS

“One-Pot” Syntheses of Malondialdehyde Adducts of Nucleosides

(2008) Jozsef Szekely et al.   NUCLEOSIDES NUCLEOTIDES & NUCLEIC ACIDS

The Chemical Toxicology of 2-Deoxyribose Oxidation in DNA

(2007) Peter C. Dedon   CHEMICAL RESEARCH IN TOXICOLOGY