The structure of the RbBP5 β-propeller domain reveals a surface with potential nucleic acid binding sites

Improvements to the APBS biomolecular solvation software suite

(2017) Elizabeth Jurrus et al.   PROTEIN SCIENCE

The new (dis)order in RNA regulation

(2016) Aino I. Järvelin et al.   Cell Communication and Signaling

High-Resolution Mapping of RNA-Binding Regions in the Nuclear Proteome of Embryonic Stem Cells

(2016) Chongsheng He et al.   MOLECULAR CELL

SONAR Discovers RNA-Binding Proteins from Analysis of Large-Scale Protein-Protein Interactomes

(2016) Kristopher W. Brannan et al.   MOLECULAR CELL

Structural basis for activity regulation of MLL family methyltransferases

(2016) Yanjing Li et al.   NATURE

HoxBlinc RNA Recruits Set1/MLL Complexes to Activate Hox Gene Expression Patterns and Mesoderm Lineage Development

(2016) Changwang Deng et al.   Cell Reports

A phosphorylation switch on RbBP5 regulates histone H3 Lys4 methylation

(2015) Pamela Zhang et al.   GENES & DEVELOPMENT

An Lnc RNA (GAS5)/SnoRNA-derived piRNA induces activation of TRAIL gene by site-specifically recruiting MLL/COMPASS-like complexes

(2015) Xin He et al.   NUCLEIC ACIDS RESEARCH

Evolving Catalytic Properties of the MLL Family SET Domain

(2015) Ying Zhang et al.   STRUCTURE

The long non-coding RNA HOTTIP enhances pancreatic cancer cell proliferation, survival and migration

(2015) Yating Cheng et al.   Oncotarget

Physical Interactions and Functional Coordination between the Core Subunits of Set1/Mll Complexes and the Reprogramming Factors

(2015) Zhenhua Yang et al.   PLoS One

Chromatin dynamics: Interplay between remodeling enzymes and histone modifications

(2014) Sarah G. Swygert et al.   Biochimica et Biophysica Acta-Gene Regulatory Mechanisms

RNAs — Physical and functional modulators of chromatin reader proteins

(2014) Kyoko Hiragami-Hamada et al.   Biochimica et Biophysica Acta-Gene Regulatory Mechanisms

Structural analysis of the KANSL1/WDR5/KANSL2 complex reveals that WDR5 is required for efficient assembly and chromatin targeting of the NSL complex

(2014) J. Dias et al.   GENES & DEVELOPMENT

A distinct set of long non-coding RNAs in childhood MLL-rearranged acute lymphoblastic leukemia: biology and epigenetic target

(2014) K. Fang et al.   HUMAN MOLECULAR GENETICS

Reactivation of maternal SNORD116 cluster via SETDB1 knockdown in Prader-Willi syndrome iPSCs

(2014) E. Cruvinel et al.   HUMAN MOLECULAR GENETICS

Transcriptional regulatory functions of nuclear long noncoding RNAs

(2014) Keith W. Vance et al.   TRENDS IN GENETICS

Essential role of lncRNA binding for WDR5 maintenance of active chromatin and embryonic stem cell pluripotency

(2014) Yul W Yang et al.   eLife

SET1 and p300 Act Synergistically, through Coupled Histone Modifications, in Transcriptional Activation by p53

(2013) Zhanyun Tang et al.   CELL

TET2 and TET3 regulate GlcNAcylation and H3K4 methylation through OGT and SET1/COMPASS

(2013) Rachel Deplus et al.   EMBO JOURNAL

A Prader–Willi locus lncRNA cloud modulates diurnal genes and energy expenditure

(2013) Weston T. Powell et al.   HUMAN MOLECULAR GENETICS

Quantitative Dissection and Stoichiometry Determination of the Human SET1/MLL Histone Methyltransferase Complexes

(2013) R. van Nuland et al.   MOLECULAR AND CELLULAR BIOLOGY

WRAD: enabler of the SET1-family of H3K4 methyltransferases

(2012) P. Ernst et al.   Briefings in Functional Genomics

ATAC-king the complexity of SAGA during evolution

(2012) G. Spedale et al.   GENES & DEVELOPMENT

Unusual Arginine Formations in Protein Function and Assembly: Rings, Strings, and Stacks

(2012) Marco A. C. Neves et al.   JOURNAL OF PHYSICAL CHEMISTRY B

The plasticity of WDR5 peptide-binding cleft enables the binding of the SET1 family of histone methyltransferases

(2012) Pamela Zhang et al.   NUCLEIC ACIDS RESEARCH

REFMAC5 for the refinement of macromolecular crystal structures

(2011) Garib N. Murshudov et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Role for Dpy-30 in ES Cell-Fate Specification by Regulation of H3K4 Methylation within Bivalent Domains

(2011) Hao Jiang et al.   CELL

Regulation of chromatin by histone modifications

(2011) Andrew J Bannister et al.   CELL RESEARCH

RETRACTED: The Noncoding RNA Mistral Activates Hoxa6 and Hoxa7 Expression and Stem Cell Differentiation by Recruiting MLL1 to Chromatin

(2011) Stéphane Bertani et al.   MOLECULAR CELL

A long noncoding RNA maintains active chromatin to coordinate homeotic gene expression

(2011) Kevin C. Wang et al.   NATURE

Structural and Biochemical Insights into MLL1 Core Complex Assembly

(2011) Vanja Avdic et al.   STRUCTURE

Structure and function of WD40 domain proteins

(2011) Chao Xu et al.   Protein & Cell

Pro Isomerization in MLL1 PHD3-Bromo Cassette Connects H3K4me Readout to CyP33 and HDAC-Mediated Repression

(2010) Zhanxin Wang et al.   CELL

Regulation of HOXA2 gene expression by the ATP-dependent chromatin remodeling enzyme CHD8

(2010) Joel A. Yates et al.   FEBS LETTERS

Characterization of a Novel WDR5-binding Site That Recruits RbBP5 through a Conserved Motif to Enhance Methylation of Histone H3 Lysine 4 by Mixed Lineage Leukemia Protein-1

(2010) Zain Odho et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Structural Basis for the Requirement of Additional Factors for MLL1 SET Domain Activity and Recognition of Epigenetic Marks

(2009) Stacey M. Southall et al.   MOLECULAR CELL

WDR5, a complexed protein

(2009) Raymond C Trievel et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

WDR5 is essential for assembly of the VISA-associated signaling complex and virus-triggered IRF3 and NF- B activation

(2009) Y.-Y. Wang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Structural Basis of UV DNA-Damage Recognition by the DDB1–DDB2 Complex

(2008) Andrea Scrima et al.   CELL

Polycomb complexes and epigenetic states

(2008) Yuri B Schwartz et al.   CURRENT OPINION IN CELL BIOLOGY

Structural basis of histone H4 recognition by p55

(2008) J.-J. Song et al.   GENES & DEVELOPMENT

Structure of WDR5 Bound to Mixed Lineage Leukemia Protein-1 Peptide

(2008) Anamika Patel et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Structural Basis for the Recognition of Histone H4 by the Histone-Chaperone RbAp46

(2008) Natalia V. Murzina et al.   STRUCTURE