Pyruvate Kinase M2 Increases Angiogenesis, Neurogenesis, and Functional Recovery Mediated by Upregulation of STAT3 and Focal Adhesion Kinase Activities After Ischemic Stroke in Adult Mice

Stem cell transplantation therapy for multifaceted therapeutic benefits after stroke

(2017) Ling Wei et al.   PROGRESS IN NEUROBIOLOGY

Regulator of G protein signaling 20 enhances cancer cell aggregation, migration, invasion and adhesion

(2016) Lei Yang et al.   CELLULAR SIGNALLING

PKM2 released by neutrophils at wound site facilitates early wound healing by promoting angiogenesis

(2016) Yinwei Zhang et al.   WOUND REPAIR AND REGENERATION

PKM2 and cancer: The function of PKM2 beyond glycolysis

(2016) GAOCHAO DONG et al.   Oncology Letters

Intranasal Delivery of Apelin-13 Is Neuroprotective and Promotes Angiogenesis After Ischemic Stroke in Mice

(2015) Dongdong Chen et al.   ASN Neuro

The Role of Pyruvate Kinase M2 in Cancer Metabolism

(2015) Vivian M. Liu et al.   BRAIN PATHOLOGY

Adaptations of energy metabolism during cerebellar neurogenesis are co-opted in medulloblastoma

(2015) Katherine Tech et al.   CANCER LETTERS

Pyruvate kinase M2 at a glance

(2015) W. Yang et al.   JOURNAL OF CELL SCIENCE

SHMT2 drives glioma cell survival in ischaemia but imposes a dependence on glycine clearance

(2015) Dohoon Kim et al.   NATURE

Pyruvate Kinase M2: Regulatory Circuits and Potential for Therapeutic Intervention

(2015) Vibhor Gupta et al.   CURRENT PHARMACEUTICAL DESIGN

No evidence for a shift in pyruvate kinase PKM1 to PKM2 expression during tumorigenesis

(2015) Katharina Bluemlein et al.   Oncotarget

Tissue-specific isoform switch and DNA hypomethylation of the pyruvate kinase PKM gene in human cancers

(2015) Shruti Desai et al.   Oncotarget

A genetic perspective on glucose consumption in the cerebral cortex during human development

(2014) J. Caravas et al.   DIABETES OBESITY & METABOLISM

Pyruvate Kinase M2 in Blood Circulation Facilitates Tumor Growth by Promoting Angiogenesis

(2014) Liangwei Li et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Mobilization of Endogenous Bone Marrow Derived Endothelial Progenitor Cells and Therapeutic Potential of Parathyroid Hormone after Ischemic Stroke in Mice

(2014) Li-Li Wang et al.   PLoS One

Reciprocal Regulation of Protein Kinase and Pyruvate Kinase Activities of Pyruvate Kinase M2 by Growth Signals

(2013) Xueliang Gao et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Insulin enhances metabolic capacities of cancer cells by dual regulation of glycolytic enzyme pyruvate kinase M2

(2013) Mohd Iqbal et al.   Molecular Cancer

Mitogenic and Oncogenic Stimulation of K433 Acetylation Promotes PKM2 Protein Kinase Activity and Nuclear Localization

(2013) Lei Lv et al.   MOLECULAR CELL

PKM2 Regulates Chromosome Segregation and Mitosis Progression of Tumor Cells

(2013) Yuhui Jiang et al.   MOLECULAR CELL

Citalopram enhances neurovascular regeneration and sensorimotor functional recovery after ischemic stroke in mice

(2013) A.R. Espinera et al.   NEUROSCIENCE

Pyruvate Kinase M2 Regulates Gene Transcription by Acting as a Protein Kinase

(2012) Xueliang Gao et al.   MOLECULAR CELL

ERK1/2-dependent phosphorylation and nuclear translocation of PKM2 promotes the Warburg effect

(2012) Weiwei Yang et al.   NATURE CELL BIOLOGY

Aerobic Glycolysis: Meeting the Metabolic Requirements of Cell Proliferation

(2011) Sophia Y. Lunt et al.   Annual Review of Cell and Developmental Biology

Rap1 promotes VEGFR2 activation and angiogenesis by a mechanism involving integrin  v 3

(2011) S. Lakshmikanthan et al.   BLOOD

Nuclear PKM2 regulates β-catenin transactivation upon EGFR activation

(2011) Weiwei Yang et al.   NATURE

Investigational Therapies for Ischemic Stroke: Neuroprotection and Neurorecovery

(2011) Preeti Sahota et al.   Neurotherapeutics

Mammalian target of rapamycin up-regulation of pyruvate kinase isoenzyme type M2 is critical for aerobic glycolysis and tumor growth

(2011) Q. Sun et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Induction of STAT3-related genes in fast degenerating cone photoreceptors of cpfl1 mice

(2010) K. Schaeferhoff et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Emerging Metabolic Targets in Cancer Therapy

(2010) Yuhua Zhao   Frontiers in Bioscience-Landmark

Evidence for an Alternative Glycolytic Pathway in Rapidly Proliferating Cells

(2010) M. G. Vander Heiden et al.   SCIENCE

Cooperation between integrin ανβ3 and VEGFR2 in angiogenesis

(2009) Payaningal R. Somanath et al.   ANGIOGENESIS

The adhesive removal test: a sensitive method to assess sensorimotor deficits in mice

(2009) Valentine Bouet et al.   Nature Protocols

Intranasal delivery of antiepileptic medications for treatment of seizures

(2009) Daniel P. Wermeling   Neurotherapeutics

Formation of Kv2.1-FAK complex as a mechanism of FAK activation, cell polarization and enhanced motility

(2008) Jian-Feng Wei et al.   JOURNAL OF CELLULAR PHYSIOLOGY