Berberine Ameliorates MCAO Induced Cerebral Ischemia/Reperfusion Injury via Activation of the BDNF–TrkB–PI3K/Akt Signaling Pathway

Berberine confers neuroprotection in coping with focal cerebral ischemia by targeting inflammatory cytokines

(2018) Solmaz Nasseri Maleki et al.   JOURNAL OF CHEMICAL NEUROANATOMY

Downregulation of Iduna is associated with AIF nuclear translocation in neonatal brain after hypoxia–ischemia

(2017) Xiaoxia Yang et al.   NEUROSCIENCE

Quercetin ameliorates ischemia/reperfusion-induced cognitive deficits by inhibiting ASK1/JNK3/caspase-3 by enhancing the Akt signaling pathway

(2016) Bing Pei et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Evidence of CCR2-independent transmigration of Ly6C hi monocytes into the brain after permanent cerebral ischemia in mice

(2016) Hannah X. Chu et al.   BRAIN RESEARCH

Metformin Attenuates Cognitive Impairments in Hypoxia–Ischemia Neonatal Rats via Improving Remyelination

(2016) Boxiang Qi et al.   CELLULAR AND MOLECULAR NEUROBIOLOGY

Berberine up-regulates the BDNF expression in hippocampus and attenuates corticosterone-induced depressive-like behavior in mice

(2016) Ji-duo Shen et al.   NEUROSCIENCE LETTERS

The Specific Protein Kinase R (PKR) Inhibitor C16 Protects Neonatal Hypoxia-Ischemia Brain Damages by Inhibiting Neuroinflammation in a Neonatal Rat Model

(2016) Jinglei Xiao et al.   MEDICAL SCIENCE MONITOR

Silencing of Id2 attenuates hypoxia/ischemia-induced neuronal injury via inhibition of neuronal apoptosis

(2015) Liemei Guo et al.   BEHAVIOURAL BRAIN RESEARCH

The Zinc Ion Chelating Agent TPEN Attenuates Neuronal Death/apoptosis Caused by Hypoxia/ischemia Via Mediating the Pathophysiological Cascade Including Excitotoxicity, Oxidative Stress, and Inflammation

(2015) Wei-Ming Wang et al.   CNS Neuroscience & Therapeutics

Berberine reduces ischemia/reperfusion-induced myocardial apoptosis via activating AMPK and PI3K–Akt signaling in diabetic rats

(2014) Keke Chen et al.   APOPTOSIS

Berberine was neuroprotective against an in vitro model of brain ischemia: Survival and apoptosis pathways involved

(2014) Elisa Nicoloso Simões Pires et al.   BRAIN RESEARCH

Testosterone enhances functional recovery after stroke through promotion of antioxidant defenses, BDNF levels and neurogenesis in male rats

(2014) Hamed Fanaei et al.   BRAIN RESEARCH

Protective effect of polydatin on learning and memory impairments in neonatal rats with hypoxic-ischemic brain injury by up-regulating brain-derived neurotrophic factor

(2014) JIN SUN et al.   Molecular Medicine Reports

Propofol Reduces Inflammatory Reaction and Ischemic Brain Damage in Cerebral Ischemia in Rats

(2014) Song-sheng Shi et al.   NEUROCHEMICAL RESEARCH

Hypoxia-inducible factor 1 mediates the anti-apoptosis of berberine in neurons during hypoxia/ischemia

(2012) Q. Zhang et al.   ACTA PHYSIOLOGICA HUNGARICA

Berberine in the Treatment of Type 2 Diabetes Mellitus: A Systemic Review and Meta-Analysis

(2012) Hui Dong et al.   Evidence-based Complementary and Alternative Medicine

Quercetin Attenuates Cell Apoptosis in Focal Cerebral Ischemia Rat Brain Via Activation of BDNF–TrkB–PI3K/Akt Signaling Pathway

(2012) Rui-Qin Yao et al.   NEUROCHEMICAL RESEARCH

The immunology of stroke: from mechanisms to translation

(2011) Costantino Iadecola et al.   NATURE MEDICINE

Apoptotic Mechanisms After Cerebral Ischemia

(2009) Brad R.S. Broughton et al.   STROKE

Berberine Induces G1 Arrest and Apoptosis in Human Glioblastoma T98G Cells through Mitochondrial/Caspases Pathway

(2008) Ki-Seong Eom et al.   BIOLOGICAL & PHARMACEUTICAL BULLETIN

Neuroprotective effects of hydrogen saline in neonatal hypoxia–ischemia rat model

(2008) Jianmei Cai et al.   BRAIN RESEARCH

Therapeutic application of gene silencing MMP-9 in a middle cerebral artery occlusion-induced focal ischemia rat model

(2008) Qin Hu et al.   EXPERIMENTAL NEUROLOGY

Neuroprotective effects of berberine on stroke models in vitro and in vivo

(2008) Xi-Qiao Zhou et al.   NEUROSCIENCE LETTERS

Neuroprotection of brain-derived neurotrophic factor against hypoxic injury in vitro requires activation of extracellular signal-regulated kinase and phosphatidylinositol 3-kinase

(2007) Xiaomei Sun et al.   INTERNATIONAL JOURNAL OF DEVELOPMENTAL NEUROSCIENCE