ERK 1/2 Activation Mediates the Neuroprotective Effect of BpV(pic) in Focal Cerebral Ischemia–Reperfusion Injury

A non-ionotropic activity of NMDA receptors contributes to glycine-induced neuroprotection in cerebral ischemia-reperfusion injury

(2017) Juan Chen et al.   Scientific Reports

Glycine confers neuroprotection through microRNA-301a/PTEN signaling

(2016) Juan Chen et al.   Molecular Brain

The RAF-MEK-ERK pathway: targeting ERK to overcome obstacles to effective cancer therapy

(2015) Zutao Yu et al.   Future Medicinal Chemistry

Neuroprotective effects of Argon are mediated via an ERK-1/2 dependent regulation of heme-oxygenase-1 in retinal ganglion cells

(2015) Felix Ulbrich et al.   JOURNAL OF NEUROCHEMISTRY

Involvement of phosphatase and tensin homolog deleted from chromosome 10 in rodent model of neuropathic pain

(2015) Shi-Ying Huang et al.   Journal of Neuroinflammation

Signaling pathway of MAPK/ERK in cell proliferation, differentiation, migration, senescence and apoptosis

(2015) Yu Sun et al.   JOURNAL OF RECEPTORS AND SIGNAL TRANSDUCTION

Administration of a PTEN inhibitor BPV(pic) attenuates early brain injury via modulating AMPA receptor subunits after subarachnoid hemorrhage in rats

(2015) Yujie Chen et al.   NEUROSCIENCE LETTERS

Neuroprotective effects of bisperoxovanadium on cerebral ischemia by inflammation inhibition

(2015) Lun-Lin Mao et al.   NEUROSCIENCE LETTERS

Circuit-dependent striatal PKA and ERK signaling underlies rapid behavioral shift in mating reaction of male mice

(2015) Akihiro Goto et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

PTEN: Multiple Functions in Human Malignant Tumors

(2015) Michele Milella et al.   Frontiers in Oncology

ERKs and mitochondria-related pathways are essential for glycyrrhizic acid-mediated neuroprotection against glutamate-induced toxicity in differentiated PC12 cells

(2014) D. Wang et al.   BRAZILIAN JOURNAL OF MEDICAL AND BIOLOGICAL RESEARCH

The FGFR/MEK/ERK/brachyury pathway is critical for chordoma cell growth and survival

(2014) Yunping Hu et al.   CARCINOGENESIS

Alpha-7 nicotinic acetylcholine receptor agonist treatment reduces neuroinflammation, oxidative stress, and brain injury in mice with ischemic stroke and bone fracture

(2014) Zhenying Han et al.   JOURNAL OF NEUROCHEMISTRY

Chemerin Induces Insulin Resistance in Rat Cardiomyocytes in Part through the ERK1/2 Signaling Pathway

(2014) Ruining Zhang et al.   PHARMACOLOGY

PTEN modulators: a patent review

(2013) Chandra S Boosani et al.   EXPERT OPINION ON THERAPEUTIC PATENTS

Tumor necrosis factor receptor-associated factor 5 is an essential mediator of ischemic brain infarction

(2013) Lang Wang et al.   JOURNAL OF NEUROCHEMISTRY

Excitotoxicity and stroke: Identifying novel targets for neuroprotection

(2013) Ted Weita Lai et al.   PROGRESS IN NEUROBIOLOGY

Neuroprotection of Ischemic Postconditioning by Downregulating the Postsynaptic Signaling Mediated by Kainate Receptors

(2013) Jing Liu et al.   STROKE

Diets involved in PPAR and PI3K/AKT/PTEN pathway may contribute to neuroprotection in a traumatic brain injury

(2013) Yasuko Kitagishi et al.   Alzheimers Research & Therapy

Regulation of nuclear TDP-43 by NR2A-containing NMDA receptors and PTEN

(2012) M. Zheng et al.   JOURNAL OF CELL SCIENCE

SHPS-1 deficiency induces robust neuroprotection against experimental stroke by attenuating oxidative stress

(2012) Lang Wang et al.   JOURNAL OF NEUROCHEMISTRY

Combination treatment with progesterone and vitamin D hormone is more effective than monotherapy in ischemic stroke: The role of BDNF/TrkB/Erk1/2 signaling in neuroprotection

(2012) Fahim Atif et al.   NEUROPHARMACOLOGY

Tyrosine kinase-independent activation of extracellular-regulated kinase (ERK) 1/2 by the insulin-like growth factor-1 receptor

(2011) Raissa Perrault et al.   CELLULAR SIGNALLING

Exogenous and autocrine growth factors stimulate human intervertebral disc cell proliferation via the ERK and Akt pathways

(2011) Harris Pratsinis et al.   JOURNAL OF ORTHOPAEDIC RESEARCH

Focal Cerebral Ischemia Model by Endovascular Suture Occlusion of the Middle Cerebral Artery in the Rat

(2011) Kutluay Uluç et al.   Jove-Journal of Visualized Experiments

PTEN deletion prevents ischemic brain injury by activating the mTOR signaling pathway

(2010) G.D. Shi et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Genetic analysis of Ras signalling pathways in cell proliferation, migration and survival

(2010) Matthias Drosten et al.   EMBO JOURNAL

Restoration of Akt activity by the bisperoxovanadium compound bpV(pic) attenuates hippocampal apoptosis in experimental neonatal pneumococcal meningitis

(2010) Matthias D. Sury et al.   NEUROBIOLOGY OF DISEASE

The Science of Stroke: Mechanisms in Search of Treatments

(2010) Michael A. Moskowitz et al.   NEURON

Preservation of GABA A Receptor Function by PTEN Inhibition Protects Against Neuronal Death in Ischemic Stroke

(2010) Baosong Liu et al.   STROKE

Regulation of PINK1 by NR2B-containing NMDA receptors in ischemic neuronal injury

(2009) Yuexin Shan et al.   JOURNAL OF NEUROCHEMISTRY

TTC, Fluoro-Jade B and NeuN staining confirm evolving phases of infarction induced by middle cerebral artery occlusion

(2009) Fudong Liu et al.   JOURNAL OF NEUROSCIENCE METHODS

Leptin protects hippocampal CA1 neurons against ischemic injury

(2008) Feng Zhang et al.   JOURNAL OF NEUROCHEMISTRY

PTEN signaling in brain: neuropathology and tumorigenesis

(2008) R Endersby et al.   ONCOGENE