Paeoniflorin Inhibits Migration and Invasion of Human Glioblastoma Cells via Suppression Transforming Growth Factor β-Induced Epithelial–Mesenchymal Transition

New Drugs from Old Natural Compounds: Scarcely Investigated Sesquiterpenes as New Possible Therapeutic Agents

(2018) Stefania Sut et al.   CURRENT MEDICINAL CHEMISTRY

Understanding the Effectiveness of Natural Compound Mixtures in Cancer through Their Molecular Mode of Action

(2017) Thazin Aung et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

The mechanism of epithelial-mesenchymal transition induced by TGF-β1 in neuroblastoma cells

(2017) Jing-Bo Shao et al.   INTERNATIONAL JOURNAL OF ONCOLOGY

Epithelial-mesenchymal transition (EMT): A biological process in the development, stem cell differentiation, and tumorigenesis

(2017) Tong Chen et al.   JOURNAL OF CELLULAR PHYSIOLOGY

The epithelial to mesenchymal transition (EMT) and cancer stem cells: implication for treatment resistance in pancreatic cancer

(2017) Pingting Zhou et al.   Molecular Cancer

EMT, CSCs, and drug resistance: the mechanistic link and clinical implications

(2017) Tsukasa Shibue et al.   Nature Reviews Clinical Oncology

Modulation of MMP-2 and MMP-9 secretion by cytokines, inducers and inhibitors in human glioblastoma T-98G cells

(2017) M. Waheed Roomi et al.   ONCOLOGY REPORTS

Decitabine reverses TGF-β1-induced epithelial–mesenchymal transition in non-small-cell lung cancer by regulating miR-200/ZEB axis

(2017) Nan Zhang et al.   Drug Design Development and Therapy

Epithelial-mesenchymal transition as a therapeutic target for overcoming chemoresistance in pancreatic cancer

(2017) Omar Elaskalani et al.   World Journal of Gastrointestinal Oncology

Paeoniflorin Ameliorates Experimental Autoimmune Encephalomyelitis via Inhibition of Dendritic Cell Function and Th17 Cell Differentiation

(2017) Han Zhang et al.   Scientific Reports

Beneficial effects of paeoniflorin on non-alcoholic fatty liver disease induced by high-fat diet in rats

(2017) Zhihong Ma et al.   Scientific Reports

Plant-Derived Urease Inhibitors as Alternative Chemotherapeutic Agents

(2016) Sherif T. S. Hassan et al.   ARCHIV DER PHARMAZIE

Paeoniflorin inhibits proliferation and invasion of breast cancer cells through suppressing Notch-1 signaling pathway

(2016) Qiang Zhang et al.   BIOMEDICINE & PHARMACOTHERAPY

Transforming growth factor-β and stem cell markers are highly expressed around necrotic areas in glioblastoma

(2016) Yasuo Iwadate et al.   JOURNAL OF NEURO-ONCOLOGY

The Epithelial-to-Mesenchymal Transition-Like Process in Glioblastoma: An Updated Systematic Review and In Silico Investigation

(2016) Isabele C. Iser et al.   MEDICINAL RESEARCH REVIEWS

Epithelial-mesenchymal transition in tumor metastasis

(2016) Kay T. Yeung et al.   Molecular Oncology

Paeoniflorin prevents hypoxia-induced epithelial–mesenchymal transition in human breast cancer cells

(2016) Zhenyu Zhou et al.   OncoTargets and Therapy

Paeoniflorin attenuates hippocampal damage in a rat model of vascular dementia

(2016) Ying Zhang et al.   Experimental and Therapeutic Medicine

Epithelial-mesenchymal transition in glioblastoma progression

(2016) YASUO IWADATE   Oncology Letters

Calycosin inhibits migration and invasion through modulation of transforming growth factor beta-mediated mesenchymal properties in U87 and U251 cells

(2016) Ru-xiang Xu et al.   Drug Design Development and Therapy

Paeoniflorin Potentiates the Inhibitory Effects of Erlotinib in Pancreatic Cancer Cell Lines by Reducing ErbB3 Phosphorylation

(2016) Jian Hao et al.   Scientific Reports

Baicalin and baicalein inhibit transforming growth factor-β1-mediated epithelial-mesenchymal transition in human breast epithelial cells

(2015) Heesung Chung et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Characterization of matrix metalloproteinase-2 and -9, ADAM-10 and N-cadherin expression in human glioblastoma multiforme

(2015) Giuseppe Musumeci et al.   CELL AND TISSUE RESEARCH

TGFβ signaling regulates epithelial–mesenchymal plasticity in ovarian cancer ascites-derived spheroids

(2015) Samah Rafehi et al.   ENDOCRINE-RELATED CANCER

Paeoniflorin inhibits proliferation and induces apoptosis of human glioma cells via microRNA-16 upregulation and matrix metalloproteinase-9 downregulation

(2015) WEIHUA LI et al.   Molecular Medicine Reports

MicroRNA-663 inhibits the proliferation, migration and invasion of glioblastoma cells via targeting TGF-β1

(2015) QIZHUANG LI et al.   ONCOLOGY REPORTS

Paeoniflorin inhibits human gastric carcinoma cell proliferation through up-regulation of microRNA-124 and suppression of PI3K/Akt and STAT3 signaling

(2015) Yong-Bin Zheng et al.   WORLD JOURNAL OF GASTROENTEROLOGY

Paeoniflorin inhibits human glioma cells via STAT3 degradation by the ubiquitin–proteasome pathway

(2015) Ru-xiang Xu et al.   Drug Design Development and Therapy

Multidimensional analysis of gene expression reveals TGFB1I1-induced EMT contributes to malignant progression of astrocytomas

(2015) Yanwei Liu et al.   Oncotarget

TGF- : Duality of Function Between Tumor Prevention and Carcinogenesis

(2014) D. R. Principe et al.   JNCI-Journal of the National Cancer Institute

TPM3, a strong prognosis predictor, is involved in malignant progression through MMP family members and EMT-like activators in gliomas

(2014) Tao Tao et al.   TUMOR BIOLOGY

TGF-β is an inducer of ZEB1-dependent mesenchymal transdifferentiation in glioblastoma that is associated with tumor invasion

(2014) J V Joseph et al.   Cell Death & Disease

Update on Anti-angiogenic Treatment for Malignant Gliomas

(2014) John F. de Groot et al.   Current Oncology Reports

Glioblastoma and Other Malignant Gliomas

(2013) Antonio Omuro   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Epithelial-to-mesenchymal(-like) transition as a relevant molecular event in malignant gliomas

(2012) U.D. Kahlert et al.   CANCER LETTERS

Power from the Garden: Plant Compounds as Inhibitors of the Hallmarks of Cancer

(2012) B. Orlikova et al.   CURRENT MEDICINAL CHEMISTRY

Glioblastoma Multiforme

(2012) Kevin Anton et al.   HEMATOLOGY-ONCOLOGY CLINICS OF NORTH AMERICA

Transfection of a human glioblastoma cell line with liver-type glutaminase (LGA) down-regulates the expression of DNA-repair gene MGMT and sensitizes the cells to alkylating agents

(2012) Monika Szeliga et al.   JOURNAL OF NEUROCHEMISTRY

Current concepts and management of glioblastoma

(2011) Matthias Preusser et al.   ANNALS OF NEUROLOGY

SNAI1 is Involved in the Proliferation and Migration of Glioblastoma Cells

(2011) Sung-Pil Han et al.   CELLULAR AND MOLECULAR NEUROBIOLOGY

Influence of Paeonia lactiflora roots extract on cAMP-phosphodiesterase activity and related anti-inflammatory action

(2011) DaiXun Jiang et al.   JOURNAL OF ETHNOPHARMACOLOGY

Gadd45a sensitizes medulloblastoma cells to irradiation and suppresses MMP-9–mediated EMT

(2011) Swapna Asuthkar et al.   NEURO-ONCOLOGY

Absence of the MGMT protein as well as methylation of the MGMT promoter predict the sensitivity for temozolomide

(2010) K A van Nifterik et al.   BRITISH JOURNAL OF CANCER

TWIST1 promotes invasion through mesenchymal change in human glioblastoma

(2010) Svetlana A Mikheeva et al.   Molecular Cancer

Epithelial-mesenchymal transitions: the importance of changing cell state in development and disease

(2009) Hervé Acloque et al.   JOURNAL OF CLINICAL INVESTIGATION

Adenovirus-mediated transfer of siRNA against MMP-2 mRNA results in impaired invasion and tumor-induced angiogenesis, induces apoptosis in vitro and inhibits tumor growth in vivo in glioblastoma

(2008) O Kargiotis et al.   ONCOGENE

Epithelial–mesenchymal transition and the invasive potential of tumors

(2008) Nancy Gavert et al.   TRENDS IN MOLECULAR MEDICINE