Geniposide Increases Unfolded Protein Response-Mediating HRD1 Expression to Accelerate APP Degradation in Primary Cortical Neurons

Energy metabolism and inflammation in brain aging and Alzheimer’s disease

(2016) Fei Yin et al.   FREE RADICAL BIOLOGY AND MEDICINE

Geniposide Attenuates the Phosphorylation of Tau Protein in Cellular and Insulin-deficient APP/PS1 Transgenic Mouse Model of Alzheimer's Disease

(2015) Yonglan Zhang et al.   Chemical Biology & Drug Design

Unfolded Protein Response and Macroautophagy in Alzheimer’s, Parkinson’s and Prion Diseases

(2015) Irina Milisav et al.   MOLECULES

Geniposide attenuates insulin-deficiency-induced acceleration of β-amyloidosis in an APP/PS1 transgenic model of Alzheimer’s disease

(2015) Yonglan Zhang et al.   NEUROCHEMISTRY INTERNATIONAL

Acute ER stress regulates amyloid precursor protein processing through ubiquitin-dependent degradation

(2015) Eun Sun Jung et al.   Scientific Reports

The roles of lipid and glucose metabolism in modulation of β-amyloid, tau, and neurodegeneration in the pathogenesis of Alzheimer disease

(2015) Naoyuki Sato et al.   Frontiers in Aging Neuroscience

Heat shock proteins and hormesis in the diagnosis and treatment of neurodegenerative diseases

(2015) Sandro Dattilo et al.   Immunity & Ageing

The role of endoplasmic reticulum in amyloid precursor protein processing and trafficking: Implications for Alzheimer's disease

(2014) A.I. Plácido et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Elevated risk of type 2 diabetes for development of Alzheimer disease: A key role for oxidative stress in brain

(2014) D. Allan Butterfield et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Oxidative stress-dependent activation of the eIF2α–ATFr unfolded protein response branch by skin sensitizer 1-fluoro-2,4-dinitrobenzene modulates dendritic-like cell maturation and inflammatory status in a biphasic manner

(2014) Andreia Luís et al.   FREE RADICAL BIOLOGY AND MEDICINE

Geniposide decreases the level of A 1-42 in the hippocampus of streptozotocin-induced diabetic rats

(2013) J. Liu et al.   ACTA BIOCHIMICA ET BIOPHYSICA SINICA

Geniposide Regulates Insulin-Degrading Enzyme Expression to Inhibit the Cytotoxicity of Aβ1-42 in Cortical Neurons

(2013) Fei Yin et al.   CNS & Neurological Disorders-Drug Targets

RETRACTED: Autoadaptive ER-Associated Degradation Defines a Preemptive Unfolded Protein Response Pathway

(2013) Riccardo Bernasconi et al.   MOLECULAR CELL

Generative FDG-PET and MRI Model of Aging and Disease Progression in Alzheimer's Disease

(2013) Juergen Dukart et al.   PLoS Computational Biology

Redox signaling loops in the unfolded protein response

(2012) Arisa Higa et al.   CELLULAR SIGNALLING

Oxidative protein folding and unfolded protein response elicit differing redox regulation in endoplasmic reticulum and cytosol of yeast

(2012) Marizela Delic et al.   FREE RADICAL BIOLOGY AND MEDICINE

Activation of the Unfolded Protein Response Is an Early Event in Alzheimer’s and Parkinson’s Disease

(2012) Jeroen J.M. Hoozemans et al.   Neurodegenerative Diseases

The unfolded protein response and proteostasis in Alzheimer disease

(2011) Wiep Scheper et al.   Autophagy

Intraneuronal amyloid β oligomers cause cell death via endoplasmic reticulum stress, endosomal/lysosomal leakage, and mitochondrial dysfunction in vivo

(2011) Tomohiro Umeda et al.   JOURNAL OF NEUROSCIENCE RESEARCH

Loss of HRD1-Mediated Protein Degradation Causes Amyloid Precursor Protein Accumulation and Amyloid-  Generation

(2010) M. Kaneko et al.   JOURNAL OF NEUROSCIENCE

Correlation Between Decrease in Protein Levels of Ubiquitin Ligase HRD1 and Amyloid-β Production

(2010) Ryo Saito et al.   JOURNAL OF PHARMACOLOGICAL SCIENCES

Brain fuel metabolism, aging, and Alzheimer’s disease

(2010) Stephen Cunnane et al.   NUTRITION

Mechanisms and Implications of Reactive Oxygen Species Generation During the Unfolded Protein Response: Roles of Endoplasmic Reticulum Oxidoreductases, Mitochondrial Electron Transport, and NADPH Oxidase

(2009) Célio X.C. Santos et al.   ANTIOXIDANTS & REDOX SIGNALING

The Stress Rheostat: An Interplay Between the Unfolded Protein Response (UPR) and Autophagy in Neurodegeneration

(2008) Soledad Matus et al.   CURRENT MOLECULAR MEDICINE

Cellular Stress Response: A Novel Target for Chemoprevention and Nutritional Neuroprotection in Aging, Neurodegenerative Disorders and Longevity

(2008) Vittorio Calabrese et al.   NEUROCHEMICAL RESEARCH