Fibroblast growth factor 23 is induced by an activated renin–angiotensin–aldosterone system in cardiac myocytes and promotes the pro-fibrotic crosstalk between cardiac myocytes and fibroblasts

Myocardial fibrosis: biomedical research from bench to bedside

(2017) Mariann Gyöngyösi et al.   EUROPEAN JOURNAL OF HEART FAILURE

Vitamin D treatment attenuates cardiac FGF23/FGFR4 signaling and hypertrophy in uremic rats

(2017) Maren Leifheit-Nestler et al.   NEPHROLOGY DIALYSIS TRANSPLANTATION

Differential Regulatory Role of Soluble Klothos on Cardiac Fibrogenesis in Hypertension

(2016) Xue Liu et al.   AMERICAN JOURNAL OF HYPERTENSION

Up-regulation of FGF23 release by aldosterone

(2016) Bingbing Zhang et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Extrarenal effects of FGF23

(2016) Dieter Haffner et al.   PEDIATRIC NEPHROLOGY

Klotho modulates FGF23-mediated NO synthesis and oxidative stress in human coronary artery endothelial cells

(2016) Beatrice Richter et al.   PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY

FGF23 promotes myocardial fibrosis in mice through activation of β-catenin

(2016) Huixin Hao et al.   Oncotarget

Klotho Ameliorates Kidney Injury and Fibrosis and Normalizes Blood Pressure by Targeting the Renin-Angiotensin System

(2015) Lili Zhou et al.   AMERICAN JOURNAL OF PATHOLOGY

Activation of Cardiac Fibroblast Growth Factor Receptor 4 Causes Left Ventricular Hypertrophy

(2015) Alexander Grabner et al.   Cell Metabolism

Antiandrogenic Therapy With Finasteride Attenuates Cardiac Hypertrophy and Left Ventricular Dysfunction

(2015) C. Zwadlo et al.   CIRCULATION

Experimental Myocardial Infarction Upregulates Circulating Fibroblast Growth Factor-23

(2015) Olena Andrukhova et al.   JOURNAL OF BONE AND MINERAL RESEARCH

The failing heart is a major source of circulating FGF23 via oncostatin M receptor activation

(2015) Manfred Richter et al.   JOURNAL OF HEART AND LUNG TRANSPLANTATION

Klotho Protects Against Indoxyl Sulphate-Induced Myocardial Hypertrophy

(2015) K. Yang et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Antiaging Gene Klotho Regulates Adrenal CYP11B2 Expression and Aldosterone Synthesis

(2015) X. Zhou et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

The ImageJ ecosystem: An open platform for biomedical image analysis

(2015) Johannes Schindelin et al.   MOLECULAR REPRODUCTION AND DEVELOPMENT

Induction of cardiac FGF23/FGFR4 expression is associated with left ventricular hypertrophy in patients with chronic kidney disease

(2015) Maren Leifheit-Nestler et al.   NEPHROLOGY DIALYSIS TRANSPLANTATION

Elevation of circulating but not myocardial FGF23 in human acute decompensated heart failure

(2015) Ingrid A. Andersen et al.   NEPHROLOGY DIALYSIS TRANSPLANTATION

Association of Fibroblast Growth Factor-23 Levels and Angiotensin-Converting Enzyme Inhibition in Chronic Systolic Heart Failure

(2015) Peter Wohlfahrt et al.   JACC-Heart Failure

Fibroblast Growth Factor-23 and Incident Atrial Fibrillation

(2014) Jehu S. Mathew et al.   CIRCULATION

Klotho and Phosphate Are Modulators of Pathologic Uremic Cardiac Remodeling

(2014) M. C. Hu et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Multiple Genes of the Renin-Angiotensin System Are Novel Targets of Wnt/ -Catenin Signaling

(2014) L. Zhou et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Exploring mechanisms of FGF signalling through the lens of structural biology

(2013) Regina Goetz et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Fibroblast growth factor-23: what we know, what we don't know, and what we need to know

(2013) C. P. Kovesdy et al.   NEPHROLOGY DIALYSIS TRANSPLANTATION

FGF-23: the rise of a novel cardiovascular risk marker in CKD

(2012) G. H. Heine et al.   NEPHROLOGY DIALYSIS TRANSPLANTATION

A Comparative Transcriptome Analysis Identifying FGF23 Regulated Genes in the Kidney of a Mouse CKD Model

(2012) Bing Dai et al.   PLoS One

The phosphatonin fibroblast growth factor 23 links calcium–phosphate metabolism with left-ventricular dysfunction and atrial fibrillation

(2011) Sarah Seiler et al.   EUROPEAN HEART JOURNAL

FGF23 induces left ventricular hypertrophy

(2011) Christian Faul et al.   JOURNAL OF CLINICAL INVESTIGATION

Fibroblast growth factor 23 is elevated before parathyroid hormone and phosphate in chronic kidney disease

(2011) Tamara Isakova et al.   KIDNEY INTERNATIONAL

Molecular mechanisms that control interstitial fibrosis in the pressure-overloaded heart

(2010) E. E. Creemers et al.   CARDIOVASCULAR RESEARCH

The opposing effects of CCN2 and CCN5 on the development of cardiac hypertrophy and fibrosis

(2010) Pyoung Oh Yoon et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Transforming growth factor (TGF)-β signaling in cardiac remodeling

(2010) Marcin Dobaczewski et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Angiotensin II blockade upregulates the expression of Klotho, the anti-ageing gene, in an experimental model of chronic cyclosporine nephropathy

(2010) H. E. Yoon et al.   NEPHROLOGY DIALYSIS TRANSPLANTATION

Fibroblast Growth Factor 23 and Left Ventricular Hypertrophy in Chronic Kidney Disease

(2009) Orlando M. Gutiérrez et al.   CIRCULATION

Role of the renin–angiotensin–aldosterone system and inflammatory processes in the development and progression of diastolic dysfunction

(2009) Sebastiano Sciarretta et al.   CLINICAL SCIENCE

Plasma Interleukin-5 Levels Are Related to Antibodies Binding to Oxidized Low-Density Lipoprotein and to Decreased Subclinical Atherosclerosis

(2008) Maritta Sämpi et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

MicroRNA-21 contributes to myocardial disease by stimulating MAP kinase signalling in fibroblasts

(2008) Thomas Thum et al.   NATURE

Fibroblast Growth Factor 23 and Mortality among Patients Undergoing Hemodialysis

(2008) Orlando M. Gutiérrez et al.   NEW ENGLAND JOURNAL OF MEDICINE

NON-CORONARY HEART DISEASE IN DIALYSIS PATIENTS: Hypertrophy and Fibrosis in the Cardiomyopathy of Uremia-Beyond Coronary Heart Disease

(2008) Marie-Luise Gross et al.   SEMINARS IN DIALYSIS