Effects of subclass change on the structural stability of chimeric, humanized, and human antibodies under thermal stress
Published 2013 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Effects of subclass change on the structural stability of chimeric, humanized, and human antibodies under thermal stress
Authors
Keywords
-
Journal
PROTEIN SCIENCE
Volume 22, Issue 11, Pages 1542-1551
Publisher
Wiley
Online
2013-08-21
DOI
10.1002/pro.2340
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Marketed therapeutic antibodies compendium
- (2012) Janice M. Reichert mAbs
- Elucidation of Acid-induced Unfolding and Aggregation of Human Immunoglobulin IgG1 and IgG2 Fc
- (2011) Ramil F. Latypov et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Advances in the assessment and control of the effector functions of therapeutic antibodies
- (2011) Xu-Rong Jiang et al. NATURE REVIEWS DRUG DISCOVERY
- High-throughput measurement, correlation analysis, and machine-learning predictions for pH and thermal stabilities of Pfizer-generated antibodies
- (2011) Amy C. King et al. PROTEIN SCIENCE
- Acid-Induced Aggregation of Human Monoclonal IgG1 and IgG2: Molecular Mechanism and the Effect of Solution Composition
- (2010) Sanjay B. Hari et al. BIOCHEMISTRY
- Influence of pH on Heat-Induced Aggregation and Degradation of Therapeutic Monoclonal Antibodies
- (2010) Tomoyoshi Ishikawa et al. BIOLOGICAL & PHARMACEUTICAL BULLETIN
- Formulation Development of Therapeutic Monoclonal Antibodies Using High-Throughput Fluorescence and Static Light Scattering Techniques: Role of Conformational and Colloidal Stability
- (2010) Deborah S. Goldberg et al. JOURNAL OF PHARMACEUTICAL SCIENCES
- IgG2m4, an engineered antibody isotype with reduced Fc function
- (2010) Zhiqiang An et al. mAbs
- Increased aggregation propensity of IgG2 subclass over IgG1: Role of conformational changes and covalent character in isolated aggregates
- (2010) Heather Franey et al. PROTEIN SCIENCE
- Immunogenicity of aggregates of recombinant human growth hormone in mouse models
- (2009) Amber Haynes Fradkin et al. JOURNAL OF PHARMACEUTICAL SCIENCES
- High throughput thermostability screening of monoclonal antibody formulations
- (2009) Feng He et al. JOURNAL OF PHARMACEUTICAL SCIENCES
- Aggregation of a multidomain protein: A coagulation mechanism governs aggregation of a model IgG1 antibody under weak thermal stress
- (2009) Christian Beyschau Andersen et al. PROTEIN SCIENCE
- Disulfide Connectivity of Human Immunoglobulin G2 Structural Isoforms
- (2008) Theresa Martinez et al. BIOCHEMISTRY
- When binding is enough: nonactivating antibody formats
- (2008) Aran F Labrijn et al. CURRENT OPINION IN IMMUNOLOGY
- Human IgG2 Antibodies Display Disulfide-mediated Structural Isoforms
- (2008) Jette Wypych et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Structural and Functional Characterization of Disulfide Isoforms of the Human IgG2 Subclass
- (2008) Thomas M. Dillon et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Human IgG2 Antibody Disulfide Rearrangementin Vivo
- (2008) Y. Diana Liu et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Fragmentation of a Recombinant Monoclonal Antibody at Various pH
- (2008) Georgeen Gaza-Bulseco et al. PHARMACEUTICAL RESEARCH
- Contribution of Variable Domains to the Stability of Humanized IgG1 Monoclonal Antibodies
- (2007) Roxana M. Ionescu et al. JOURNAL OF PHARMACEUTICAL SCIENCES
Add your recorded webinar
Do you already have a recorded webinar? Grow your audience and get more views by easily listing your recording on Peeref.
Upload NowBecome a Peeref-certified reviewer
The Peeref Institute provides free reviewer training that teaches the core competencies of the academic peer review process.
Get Started