CARD9S12N facilitates the production of IL-5 by alveolar macrophages for the induction of type 2 immune responses

JNK1 negatively controls antifungal innate immunity by suppressing CD23 expression

(2017) Xueqiang Zhao et al.   NATURE MEDICINE

Host DNA released by NETosis promotes rhinovirus-induced type-2 allergic asthma exacerbation

(2017) Marie Toussaint et al.   NATURE MEDICINE

Insights into Group 2 Innate Lymphoid Cells in Human Airway Disease

(2016) Maya R. Karta et al.   CURRENT ALLERGY AND ASTHMA REPORTS

Recognition of Aspergillus fumigatus Hyphae by Human Plasmacytoid Dendritic Cells Is Mediated by Dectin-2 and Results in Formation of Extracellular Traps

(2015) Flávio V. Loures et al.   PLoS Pathogens

CARD9 Deficiency and Spontaneous Central Nervous System Candidiasis: Complete Clinical Remission With GM-CSF Therapy

(2014) C. Gavino et al.   CLINICAL INFECTIOUS DISEASES

C-type Lectin Receptor Dectin-3 Mediates Trehalose 6,6′-Dimycolate (TDM)-induced Mincle Expression through CARD9/Bcl10/MALT1-dependent Nuclear Factor (NF)-κB Activation

(2014) Xue-Qiang Zhao et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

CARD9 mediates Dectin-1–induced ERK activation by linking Ras-GRF1 to H-Ras for antifungal immunity

(2014) Xin-Ming Jia et al.   JOURNAL OF EXPERIMENTAL MEDICINE

A CARD9 Polymorphism Is Associated with Decreased Likelihood of Persistent Conjugated Hyperbilirubinemia in Intestinal Failure

(2014) Karolina Maria Burghardt et al.   PLoS One

Gene polymorphisms in pattern recognition receptors and susceptibility to idiopathic recurrent vulvovaginal candidiasis

(2014) Diana C. Rosentul et al.   Frontiers in Microbiology

One-Step Generation of Mice Carrying Reporter and Conditional Alleles by CRISPR/Cas-Mediated Genome Engineering

(2013) Hui Yang et al.   CELL

Deep Dermatophytosis and Inherited CARD9 Deficiency

(2013) Fanny Lanternier et al.   NEW ENGLAND JOURNAL OF MEDICINE

FLT3/D835Y mutation knock-in mice display less aggressive disease compared with FLT3/internal tandem duplication (ITD) mice

(2013) E. Bailey et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mepolizumab for severe eosinophilic asthma

(2013) Douglas S Robinson   Expert Review of Respiratory Medicine

Tracing Conidial Fate and Measuring Host Cell Antifungal Activity Using a Reporter of Microbial Viability in the Lung

(2012) Anupam Jhingran et al.   Cell Reports

Benralizumab – a humanized mAb to IL-5Rα with enhanced antibody-dependent cell-mediated cytotoxicity – a novel approach for the treatment of asthma

(2011) Aasia Ghazi et al.   EXPERT OPINION ON BIOLOGICAL THERAPY

Three ulcerative colitis susceptibility loci are associated with primary sclerosing cholangitis and indicate a role for IL2, REL, and CARD9

(2011) Marcel Janse et al.   HEPATOLOGY

Dectin-1 diversifiesAspergillus fumigatus–specific T cell responses by inhibiting T helper type 1 CD4 T cell differentiation

(2011) Amariliz Rivera et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Genetic Variation in the Dectin-1/CARD9 Recognition Pathway and Susceptibility to Candidemia

(2011) Diana C. Rosentul et al.   JOURNAL OF INFECTIOUS DISEASES

Deep resequencing of GWAS loci identifies independent rare variants associated with inflammatory bowel disease

(2011) Manuel A Rivas et al.   NATURE GENETICS

Malt1-dependent RelB cleavage promotes canonical NF- B activation in lymphocytes and lymphoma cell lines

(2011) S. Hailfinger et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

TNF-  from inflammatory dendritic cells (DCs) regulates lung IL-17A/IL-5 levels and neutrophilia versus eosinophilia during persistent fungal infection

(2011) M. Fei et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Protein structure analysis of mutations causing inheritable diseases. An e-Science approach with life scientist friendly interfaces

(2010) Hanka Venselaar et al.   BMC BIOINFORMATICS

Genome-wide association identifies multiple ulcerative colitis susceptibility loci

(2010) Dermot P B McGovern et al.   NATURE GENETICS

Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci

(2010) Andre Franke et al.   NATURE GENETICS

A HomozygousCARD9Mutation in a Family with Susceptibility to Fungal Infections

(2009) Erik-Oliver Glocker et al.   NEW ENGLAND JOURNAL OF MEDICINE

CARD9 versus CARMA1 in innate and adaptive immunity

(2009) Hiromitsu Hara et al.   TRENDS IN IMMUNOLOGY