CARD9 mediates Dectin-1–induced ERK activation by linking Ras-GRF1 to H-Ras for antifungal immunity

C-Type Lectin Receptors Dectin-3 and Dectin-2 Form a Heterodimeric Pattern-Recognition Receptor for Host Defense against Fungal Infection

(2013) Le-Le Zhu et al.   IMMUNITY

CARD9 mutations linked to subcutaneous phaeohyphomycosis and TH17 cell deficiencies

(2013) Xiaowen Wang et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Deep Dermatophytosis and Inherited CARD9 Deficiency

(2013) Fanny Lanternier et al.   NEW ENGLAND JOURNAL OF MEDICINE

Ras-guanine-nucleotide-releasing factors 1 and 2 interact with PLCγ at focal adhesions to enable IL-1-induced Ca2+signalling, ERK activation and MMP-3 expression

(2012) Qin Wang et al.   BIOCHEMICAL JOURNAL

C-type lectin receptor-induced NF-κB activation in innate immune and inflammatory responses

(2012) Lara M Kingeter et al.   Cellular & Molecular Immunology

C-type lectin SIGNR1 enhances cellular oxidative burst response against C. albicans in cooperation with Dectin-1

(2011) Kazuhiko Takahara et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Phospholipase Cγ2 (PLCγ2) Is Key Component in Dectin-2 Signaling Pathway, Mediating Anti-fungal Innate Immune Responses

(2011) Sara Gorjestani et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Y238X Stop Codon Polymorphism in the Human β-Glucan Receptor Dectin-1 and Susceptibility to Invasive Aspergillosis

(2011) Louis Y.A. Chai et al.   JOURNAL OF INFECTIOUS DISEASES

Activation and Function of the MAPKs and Their Substrates, the MAPK-Activated Protein Kinases

(2011) M. Cargnello et al.   MICROBIOLOGY AND MOLECULAR BIOLOGY REVIEWS

Activation of the innate immune receptor Dectin-1 upon formation of a ‘phagocytic synapse’

(2011) Helen S. Goodridge et al.   NATURE

Fungal recognition is mediated by the association of dectin-1 and galectin-3 in macrophages

(2011) A. Esteban et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Syk-coupled C-type lectins in immunity

(2011) Ann M. Kerrigan et al.   TRENDS IN IMMUNOLOGY

Dectin-1 Y238X polymorphism associates with susceptibility to invasive aspergillosis in hematopoietic transplantation through impairment of both recipient- and donor-dependent mechanisms of antifungal immunity

(2010) C. Cunha et al.   BLOOD

A Biphasic Innate Immune MAPK Response Discriminates between the Yeast and Hyphal Forms of Candida albicans in Epithelial Cells

(2010) David L. Moyes et al.   Cell Host & Microbe

The incidence of acute graft-versus-host disease increases with Candida colonization depending the dectin-1 gene status

(2010) Walter J.F.M. van der Velden et al.   CLINICAL IMMUNOLOGY

Dectin-2 Recognition of α-Mannans and Induction of Th17 Cell Differentiation Is Essential for Host Defense against Candida albicans

(2010) Shinobu Saijo et al.   IMMUNITY

Candida albicans  -Glucan Exposure Is Controlled by the Fungal CEK1-Mediated Mitogen-Activated Protein Kinase Pathway That Modulates Immune Responses Triggered through Dectin-1

(2010) M. Galan-Diez et al.   INFECTION AND IMMUNITY

CARD9 Mediates Dectin-2-induced IκBα Kinase Ubiquitination Leading to Activation of NF-κB in Response to Stimulation by the Hyphal Form ofCandida albicans

(2010) Liangkuan Bi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Cutting Edge: Mincle Is Essential for Recognition and Adjuvanticity of the Mycobacterial Cord Factor and its Synthetic Analog Trehalose-Dibehenate

(2010) H. Schoenen et al.   JOURNAL OF IMMUNOLOGY

Deletion of the Candida albicans histidine kinase gene CHK1 improves recognition by phagocytes through an increased exposure of cell wall  -1,3-glucans

(2010) N. Klippel et al.   MICROBIOLOGY-SGM

Regulation and Function of NF-κB Transcription Factors in the Immune System

(2009) Sivakumar Vallabhapurapu et al.   Annual Review of Immunology

Early Stop Polymorphism in Human DECTIN‐1 Is Associated with IncreasedCandidaColonization in Hematopoietic Stem Cell Transplant Recipients

(2009) Theo S. Plantinga et al.   CLINICAL INFECTIOUS DISEASES

Approaching the Asymptote: 20 Years Later

(2009) Ruslan Medzhitov   IMMUNITY

BLNK Binds Active H-Ras to Promote B Cell Receptor-mediated Capping and ERK Activation

(2009) Yasuhiro Imamura et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Dectin-2 is a Syk-coupled pattern recognition receptor crucial for Th17 responses to fungal infection

(2009) Matthew J. Robinson et al.   JOURNAL OF EXPERIMENTAL MEDICINE

CARD9 facilitates microbe-elicited production of reactive oxygen species by regulating the LyGDI-Rac1 complex

(2009) Weihui Wu et al.   NATURE IMMUNOLOGY

Dectin-1 directs T helper cell differentiation by controlling noncanonical NF-κB activation through Raf-1 and Syk

(2009) Sonja I Gringhuis et al.   NATURE IMMUNOLOGY

Human Dectin-1 Deficiency and Mucocutaneous Fungal Infections

(2009) Bart Ferwerda et al.   NEW ENGLAND JOURNAL OF MEDICINE

A HomozygousCARD9Mutation in a Family with Susceptibility to Fungal Infections

(2009) Erik-Oliver Glocker et al.   NEW ENGLAND JOURNAL OF MEDICINE

Dectin-1 synergizes with TLR2 and TLR4 for cytokine production in human primary monocytes and macrophages

(2008) Gerben Ferwerda et al.   CELLULAR MICROBIOLOGY

Dynamic, Morphotype-Specific Candida albicans β-Glucan Exposure during Infection and Drug Treatment

(2008) Robert T. Wheeler et al.   PLoS Pathogens

Stage-Specific Sampling by Pattern Recognition Receptors during Candida albicans Phagocytosis

(2008) Sigrid E. M. Heinsbroek et al.   PLoS Pathogens

Induction of ERK-kinase signalling triggers morphotype-specific killing of Candida albicans filaments by human neutrophils

(2007) Iwona Wozniok et al.   CELLULAR MICROBIOLOGY