Non-invasive perturbations of intracellular flow reveal physical principles of cell organization

Cortical forces and CDC-42 control clustering of PAR proteins for Caenorhabditis elegans embryonic polarization

(2017) Shyi-Chyi Wang et al.   NATURE CELL BIOLOGY

Size- and speed-dependent mechanical behavior in living mammalian cytoplasm

(2017) Jiliang Hu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Active matter at the interface between materials science and cell biology

(2017) Daniel Needleman et al.   Nature Reviews Materials

Polar Positioning of Phase-Separated Liquid Compartments in Cells Regulated by an mRNA Competition Mechanism

(2016) Shambaditya Saha et al.   CELL

Cilia-based flow network in the brain ventricles

(2016) R. Faubel et al.   SCIENCE

A pH-driven transition of the cytoplasm from a fluid- to a solid-like state promotes entry into dormancy

(2016) Matthias Christoph Munder et al.   eLife

A glucose-starvation response regulates the diffusion of macromolecules

(2016) Ryan P Joyner et al.   eLife

Cortical flow aligns actin filaments to form a furrow

(2016) Anne-Cecile Reymann et al.   eLife

Software concepts and numerical algorithms for a scalable adaptive parallel finite element method

(2015) T. Witkowski et al.   ADVANCES IN COMPUTATIONAL MATHEMATICS

Reversible, Specific, Active Aggregates of Endogenous Proteins Assemble upon Heat Stress

(2015) Edward W.J. Wallace et al.   CELL

Propagating gene expression fronts in a one-dimensional coupled system of artificial cells

(2015) Alexandra M. Tayar et al.   Nature Physics

Active gel physics

(2015) J. Prost et al.   Nature Physics

A physical perspective on cytoplasmic streaming

(2015) R. E. Goldstein et al.   Interface Focus

Temperature Dependence of Cell Division Timing Accounts for a Shift in the Thermal Limits of C. elegans and C. briggsae

(2015) Maria L. Begasse et al.   Cell Reports

Probing the Stochastic, Motor-Driven Properties of the Cytoplasm Using Force Spectrum Microscopy

(2014) Ming Guo et al.   CELL

TNF and IL-1 exhibit distinct ubiquitin requirements for inducing NEMO–IKK supramolecular structures

(2014) Nadine Tarantino et al.   JOURNAL OF CELL BIOLOGY

The heat released during catalytic turnover enhances the diffusion of an enzyme

(2014) Clement Riedel et al.   NATURE

Apical constriction drives tissue-scale hydrodynamic flow to mediate cell elongation

(2014) Bing He et al.   NATURE

The Bacterial Cytoplasm Has Glass-like Properties and Is Fluidized by Metabolic Activity

(2013) Bradley R. Parry et al.   CELL

Morphogen transport

(2013) P. Muller et al.   DEVELOPMENT

Image-based analysis of lipid nanoparticle–mediated siRNA delivery, intracellular trafficking and endosomal escape

(2013) Jerome Gilleron et al.   NATURE BIOTECHNOLOGY

Principles of PAR polarity in Caenorhabditis elegans embryos

(2013) Carsten Hoege et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Stability of Localized Wave Fronts in Bistable Systems

(2013) Steffen Rulands et al.   PHYSICAL REVIEW LETTERS

Fiji: an open-source platform for biological-image analysis

(2012) Johannes Schindelin et al.   NATURE METHODS

Cytoplasmic streaming in Drosophila oocytes varies with kinesin activity and correlates with the microtubule cytoskeleton architecture

(2012) S. Ganguly et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Microtubules induce self-organization of polarized PAR domains in Caenorhabditis elegans zygotes

(2011) Fumio Motegi et al.   NATURE CELL BIOLOGY

Turing's next steps: the mechanochemical basis of morphogenesis

(2011) Jonathon Howard et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Polarization of PAR Proteins by Advective Triggering of a Pattern-Forming System

(2011) N. W. Goehring et al.   SCIENCE

Cortical domain correction repositions the polarity boundary to match the cytokinesis furrow in C. elegans embryos

(2010) C. Schenk et al.   DEVELOPMENT

Anisotropies in cortical tension reveal the physical basis of polarizing cortical flows

(2010) Mirjam Mayer et al.   NATURE

Reaction-Diffusion Model as a Framework for Understanding Biological Pattern Formation

(2010) S. Kondo et al.   SCIENCE

Nuclear Architecture of Rod Photoreceptor Cells Adapts to Vision in Mammalian Evolution

(2009) Irina Solovei et al.   CELL

Determining the scale of the Bicoid morphogen gradient

(2009) Inbal Hecht et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Germline P Granules Are Liquid Droplets That Localize by Controlled Dissolution/Condensation

(2009) C. P. Brangwynne et al.   SCIENCE

Characterization of Protein Dynamics in Asymmetric Cell Division by Scanning Fluorescence Correlation Spectroscopy

(2008) Zdeněk Petrášek et al.   BIOPHYSICAL JOURNAL

Optically driven fluid flow along arbitrary microscale patterns using thermoviscous expansion

(2008) Franz M. Weinert et al.   JOURNAL OF APPLIED PHYSICS

Cytoplasmic diffusion: molecular motors mix it up

(2008) Clifford P. Brangwynne et al.   JOURNAL OF CELL BIOLOGY

Microscale Fluid Flow Induced by Thermoviscous Expansion Along a Traveling Wave

(2008) Franz M. Weinert et al.   PHYSICAL REVIEW LETTERS

Spatial Regulators for Bacterial Cell Division Self-Organize into Surface Waves in Vitro

(2008) M. Loose et al.   SCIENCE