Defining essential genes for human pluripotent stem cells by CRISPR–Cas9 screening in haploid cells

Human pluripotent stem cells recurrently acquire and expand dominant negative P53 mutations

(2017) Florian T. Merkle et al.   NATURE

Haploid Human Embryonic Stem Cells: Half the Genome, Double the Value

(2016) Atilgan Yilmaz et al.   Cell Stem Cell

Derivation and differentiation of haploid human embryonic stem cells

(2016) Ido Sagi et al.   NATURE

Identification and propagation of haploid human pluripotent stem cells

(2016) Ido Sagi et al.   Nature Protocols

Pluripotent stem cells in disease modelling and drug discovery

(2016) Yishai Avior et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Cripto is essential to capture mouse epiblast stem cell and human embryonic stem cell pluripotency

(2016) Alessandro Fiorenzano et al.   Nature Communications

Tuberous sclerosis complex

(2016) Elizabeth P. Henske et al.   Nature Reviews Disease Primers

High-Resolution CRISPR Screens Reveal Fitness Genes and Genotype-Specific Cancer Liabilities

(2015) Traver Hart et al.   CELL

Hallmarks of pluripotency

(2015) Alejandro De Los Angeles et al.   NATURE

The oncogene c-Jun impedes somatic cell reprogramming

(2015) Jing Liu et al.   NATURE CELL BIOLOGY

Gene essentiality and synthetic lethality in haploid human cells

(2015) V. A. Blomen et al.   SCIENCE

Identification and characterization of essential genes in the human genome

(2015) T. Wang et al.   SCIENCE

Epigenetic Biomarker to Support Classification into Pluripotent and Non-Pluripotent Cells

(2015) Michael Lenz et al.   Scientific Reports

Haploid Mouse Embryonic Stem Cells: Rapid Genetic Screening and Germline Transmission

(2014) Anton Wutz   Annual Review of Cell and Developmental Biology

COMPARTMENTS: unification and visualization of protein subcellular localization evidence

(2014) J. X. Binder et al.   Database-The Journal of Biological Databases and Curation

Generation of haploid embryonic stem cells from Macaca fascicularis monkey parthenotes

(2013) Hui Yang et al.   CELL RESEARCH

Genetic Modification and Screening in Rat Using Haploid Embryonic Stem Cells

(2013) Wei Li et al.   Cell Stem Cell

Genome-Scale CRISPR-Cas9 Knockout Screening in Human Cells

(2013) Ophir Shalem et al.   SCIENCE

Generation of Genetically Modified Mice by Oocyte Injection of Androgenetic Haploid Embryonic Stem Cells

(2012) Hui Yang et al.   CELL

Androgenetic haploid embryonic stem cells produce live transgenic mice

(2012) Wei Li et al.   NATURE

Fast gapped-read alignment with Bowtie 2

(2012) Ben Langmead et al.   NATURE METHODS

Monoallelic Expression Determines Oncogenic Progression and Outcome in Benign and Malignant Brain Tumors

(2011) E. J. Walker et al.   CANCER RESEARCH

Forward and Reverse Genetics through Derivation of Haploid Mouse Embryonic Stem Cells

(2011) Ulrich Elling et al.   Cell Stem Cell

Derivation of haploid embryonic stem cells from mouse embryos

(2011) Martin Leeb et al.   NATURE

Knockdown of Fanconi anemia genes in human embryonic stem cells reveals early developmental defects in the hematopoietic lineage

(2010) A. Tulpule et al.   BLOOD

An Atlas of Combinatorial Transcriptional Regulation in Mouse and Man

(2010) Timothy Ravasi et al.   CELL

Disease-corrected haematopoietic progenitors from Fanconi anaemia induced pluripotent stem cells

(2009) Ángel Raya et al.   NATURE

Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources

(2009) Da Wei Huang et al.   Nature Protocols

mTOR supports long-term self-renewal and suppresses mesoderm and endoderm activities of human embryonic stem cells

(2009) J. Zhou et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Haploid Genetic Screens in Human Cells Identify Host Factors Used by Pathogens

(2009) J. E. Carette et al.   SCIENCE

The Pharmacology of mTOR Inhibition

(2009) D. A. Guertin et al.   Science Signaling

Rex1/Zfp42 is dispensable for pluripotency in mouse ES cells

(2008) Shinji Masui et al.   BMC DEVELOPMENTAL BIOLOGY

An Extended Transcriptional Network for Pluripotency of Embryonic Stem Cells

(2008) Jonghwan Kim et al.   CELL