Derivation and differentiation of haploid human embryonic stem cells

Optimized sgRNA design to maximize activity and minimize off-target effects of CRISPR-Cas9

(2016) John G Doench et al.   NATURE BIOTECHNOLOGY

Differentiation of hypothalamic-like neurons from human pluripotent stem cells

(2015) Liheng Wang et al.   JOURNAL OF CLINICAL INVESTIGATION

Haploid Mouse Embryonic Stem Cells: Rapid Genetic Screening and Germline Transmission

(2014) Anton Wutz   Annual Review of Cell and Developmental Biology

Generation of Functional Human Pancreatic β Cells In Vitro

(2014) Felicia W. Pagliuca et al.   CELL

Comparable Frequencies of Coding Mutations and Loss of Imprinting in Human Pluripotent Cells Derived by Nuclear Transfer and Defined Factors

(2014) Bjarki Johannesson et al.   Cell Stem Cell

Induction of the G2/M transition stabilizes haploid embryonic stem cells

(2014) S. Takahashi et al.   DEVELOPMENT

Mitochondrial remodeling in hepatic differentiation and dedifferentiation

(2014) Anaïs Wanet et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Human oocytes reprogram adult somatic nuclei of a type 1 diabetic to diploid pluripotent stem cells

(2014) Mitsutoshi Yamada et al.   NATURE

Reversal of diabetes with insulin-producing cells derived in vitro from human pluripotent stem cells

(2014) Alireza Rezania et al.   NATURE BIOTECHNOLOGY

Transposon activation mutagenesis as a screening tool for identifying resistance to cancer therapeutics

(2013) Li Chen et al.   BMC CANCER

Generation of haploid embryonic stem cells from Macaca fascicularis monkey parthenotes

(2013) Hui Yang et al.   CELL RESEARCH

Genetic Modification and Screening in Rat Using Haploid Embryonic Stem Cells

(2013) Wei Li et al.   Cell Stem Cell

iPSC-derived β cells model diabetes due to glucokinase deficiency

(2013) Haiqing Hua et al.   JOURNAL OF CLINICAL INVESTIGATION

The Genotype-Tissue Expression (GTEx) project

(2013) John Lonsdale et al.   NATURE GENETICS

Immunologic and chemical targeting of the tight-junction protein Claudin-6 eliminates tumorigenic human pluripotent stem cells

(2013) Uri Ben-David et al.   Nature Communications

Involvement of parental imprinting in the antisense regulation of onco-miR-372-373

(2013) Yonatan Stelzer et al.   Nature Communications

Human Pluripotent Stem Cells with Distinct X Inactivation Status Show Molecular and Cellular Differences Controlled by the X-Linked ELK-1 Gene

(2013) Tal Bruck et al.   Cell Reports

Revisiting Global Gene Expression Analysis

(2012) Jakob Lovén et al.   CELL

Generation of Genetically Modified Mice by Oocyte Injection of Androgenetic Haploid Embryonic Stem Cells

(2012) Hui Yang et al.   CELL

Germline potential of parthenogenetic haploid mouse embryonic stem cells

(2012) M. Leeb et al.   DEVELOPMENT

Nuclear genome transfer in human oocytes eliminates mitochondrial DNA variants

(2012) Daniel Paull et al.   NATURE

Androgenetic haploid embryonic stem cells produce live transgenic mice

(2012) Wei Li et al.   NATURE

Directed cardiomyocyte differentiation from human pluripotent stem cells by modulating Wnt/β-catenin signaling under fully defined conditions

(2012) Xiaojun Lian et al.   Nature Protocols

The in vitro survival of human monosomies and trisomies as embryonic stem cells

(2012) Juan Carlos Biancotti et al.   Stem Cell Research

Impracticality of Egg Donor Recruitment in the Absence of Compensation

(2011) Dieter Egli et al.   Cell Stem Cell

Forward and Reverse Genetics through Derivation of Haploid Mouse Embryonic Stem Cells

(2011) Ulrich Elling et al.   Cell Stem Cell

Human oocytes reprogram somatic cells to a pluripotent state

(2011) Scott Noggle et al.   NATURE

Derivation of haploid embryonic stem cells from mouse embryos

(2011) Martin Leeb et al.   NATURE

Robust Enhancement of Neural Differentiation from Human ES and iPS Cells Regardless of their Innate Difference in Differentiation Propensity

(2010) Dae-Sung Kim et al.   Stem Cell Reviews and Reports

Optimal Timing of Inner Cell Mass Isolation Increases the Efficiency of Human Embryonic Stem Cell Derivation and Allows Generation of Sibling Cell Lines

(2009) Alice E. Chen et al.   Cell Stem Cell

Highly efficient neural conversion of human ES and iPS cells by dual inhibition of SMAD signaling

(2009) Stuart M Chambers et al.   NATURE BIOTECHNOLOGY

X-chromosome inactivation and epigenetic fluidity in human embryonic stem cells

(2008) S. S. Silva et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Chromosomal transposition of PiggyBac in mouse embryonic stem cells

(2008) W. Wang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA