Multiplexed precision genome editing with trackable genomic barcodes in yeast

Evolved Cas9 variants with broad PAM compatibility and high DNA specificity

(2018) Johnny H. Hu et al.   NATURE

A method for high‐throughput production of sequence‐verified DNA libraries and strain collections

(2017) Justin D Smith et al.   Molecular Systems Biology

Enhanced proofreading governs CRISPR–Cas9 targeting accuracy

(2017) Janice S. Chen et al.   NATURE

CRISPR-UMI: single-cell lineage tracing of pooled CRISPR–Cas9 screens

(2017) Georg Michlits et al.   NATURE METHODS

High-fidelity CRISPR–Cas9 nucleases with no detectable genome-wide off-target effects

(2016) Benjamin P. Kleinstiver et al.   NATURE

Genome-wide mapping of mutations at single-nucleotide resolution for protein, metabolic and genome engineering

(2016) Andrew D Garst et al.   NATURE BIOTECHNOLOGY

Optimized sgRNA design to maximize activity and minimize off-target effects of CRISPR-Cas9

(2016) John G Doench et al.   NATURE BIOTECHNOLOGY

Distinct patterns of Cas9 mismatch tolerancein vitroandin vivo

(2016) Becky X.H. Fu et al.   NUCLEIC ACIDS RESEARCH

Binding of the Fkh1 Forkhead Associated Domain to a Phosphopeptide within the Mph1 DNA Helicase Regulates Mating-Type Switching in Budding Yeast

(2016) Antoinette M. Dummer et al.   PLoS Genetics

Rationally engineered Cas9 nucleases with improved specificity

(2015) I. M. Slaymaker et al.   SCIENCE

Rational design of highly active sgRNAs for CRISPR-Cas9–mediated gene inactivation

(2014) John G Doench et al.   NATURE BIOTECHNOLOGY

Selection of chromosomal DNA libraries using a multiplex CRISPR system

(2014) Owen W Ryan et al.   eLife

DNA targeting specificity of RNA-guided Cas9 nucleases

(2013) Patrick D Hsu et al.   NATURE BIOTECHNOLOGY

PITPs as targets for selectively interfering with phosphoinositide signaling in cells

(2013) Aaron H Nile et al.   Nature Chemical Biology

Genome engineering in Saccharomyces cerevisiae using CRISPR-Cas systems

(2013) James E. DiCarlo et al.   NUCLEIC ACIDS RESEARCH

Transcription termination by the eukaryotic RNA polymerase III

(2012) Aneeshkumar G. Arimbasseri et al.   Biochimica et Biophysica Acta-Gene Regulatory Mechanisms

Differential expression analysis of multifactor RNA-Seq experiments with respect to biological variation

(2012) Davis J. McCarthy et al.   NUCLEIC ACIDS RESEARCH

Regulation of Budding Yeast Mating-Type Switching Donor Preference by the FHA Domain of Fkh1

(2012) Jin Li et al.   PLoS Genetics

Dynamics of DNA damage response proteins at DNA breaks: a focus on protein modifications

(2011) S. E. Polo et al.   GENES & DEVELOPMENT

SEC14 is a specific requirement for secretion of phospholipase B1 and pathogenicity of Cryptococcus neoformans

(2011) Methee Chayakulkeeree et al.   MOLECULAR MICROBIOLOGY

Widespread occurrence of non-canonical transcription termination by human RNA polymerase III

(2011) Andrea Orioli et al.   NUCLEIC ACIDS RESEARCH

edgeR: a Bioconductor package for differential expression analysis of digital gene expression data

(2009) M. D. Robinson et al.   BIOINFORMATICS