Enantioselective palladium-catalyzed allylic alkylation reactions in the synthesis of Aspidosperma and structurally related monoterpene indole alkaloids

Tandem Intramolecular Diels–Alder/1,3-Dipolar Cycloaddition Cascade of 1,3,4-Oxadiazoles: Initial Scope and Applications

(2016) Justin E. Sears et al.   ACCOUNTS OF CHEMICAL RESEARCH

Enantioselective Pd-Catalyzed Allylic Alkylation Reactions of Dihydropyrido[1,2-a ]indolone Substrates: Efficient Syntheses of (−)-Goniomitine, (+)-Aspidospermidine, and (−)-Quebrachamine

(2016) Beau P. Pritchett et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Concise Total Syntheses of (+)-Haplocidine and (+)-Haplocine via Late-Stage Oxidation of (+)-Fendleridine Derivatives

(2016) Kolby L. White et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Enantioselective Total Syntheses of (−)-Rhazinilam, (−)-Leucomidine B, and (+)-Leuconodine F

(2015) Dylan Dagoneau et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Direct Observation of Intermediates Involved in the Interruption of the Bischler–Napieralski Reaction

(2015) Kolby L. White et al.   JOURNAL OF ORGANIC CHEMISTRY

Total Syntheses of (−)-Mersicarpine, (−)-Scholarisine G, (+)-Melodinine E, (−)-Leuconoxine, (−)-Leuconolam, (−)-Leuconodine A, (+)-Leuconodine F, and (−)-Leuconodine C: Self-Induced Diastereomeric Anisochronism (SIDA) Phenomenon for Scholarisine G and Leuconodines A and C

(2015) Zhengren Xu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Palladium-Catalyzed Enantioselective Decarboxylative Allylic Alkylation of Cyclopentanones

(2015) Robert A. Craig et al.   ORGANIC LETTERS

Synthesis and exploration of electronically modified (R)-5,5-dimethyl-(p-CF3)3-i-PrPHOX in palladium-catalyzed enantio- and diastereoselective allylic alkylation: a practical alternative to (R)-(p-CF3)3-t-BuPHOX

(2015) Robert A. Craig et al.   TETRAHEDRON LETTERS

Selective syntheses of leuconolam, leuconoxine, and mersicarpine alkaloids from a common intermediate through regiocontrolled cyclizations by Staudinger reactions

(2015) Zining Li et al.   Organic Chemistry Frontiers

Formal total syntheses of classic natural product target molecules via palladium-catalyzed enantioselective alkylation

(2014) Yiyang Liu et al.   Beilstein Journal of Organic Chemistry

Total synthesis of (+)-kopsihainanine A

(2014) Masaya Mizutani et al.   CHEMICAL COMMUNICATIONS

Catalytic Enantioselective and Divergent Total Synthesis of (+)-10-Oxocylindrocarpidine, (+)-Cylindrocarpidine, (−)-N-Acetylcylindrocarpinol, and (+)-Aspidospermine

(2014) Xiao-Lei Shen et al.   JOURNAL OF ORGANIC CHEMISTRY

Unified Strategy to Monoterpene Indole Alkaloids: Total Syntheses of (±)-Goniomitine, (±)-1,2-Dehydroaspidospermidine, (±)-Aspidospermidine, (±)-Vincadifformine, and (±)-Kopsihainanine A

(2014) Olivier Wagnières et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Biosynthetically Inspired Divergent Approach to Monoterpene Indole Alkaloids: Total Synthesis of Mersicarpine, Leuconodines B and D, Leuconoxine, Melodinine E, Leuconolam, and Rhazinilam

(2014) Yang Yang et al.   ORGANIC LETTERS

Palladium-Catalyzed Intermolecular Asymmetric Allylic Dearomatization Reaction of Naphthol Derivatives

(2013) Chun-Xiang Zhuo et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Enantioselective Palladium-Catalyzed Decarboxylative Allylation of Carbazolones: Total Synthesis of (−)-Aspidospermidine and (+)-Kopsihainanine A

(2013) Zeqian Li et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Total Synthesis of the Indole Alkaloid (±)- and (+)-MethylN-Decarbomethoxychanofruticosinate

(2013) Yi Wei et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

General Entry to Aspidosperma Alkaloids: Enantioselective Total Synthesis of (−)-Aspidophytine

(2013) Rongwen Yang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Enantioselective Palladium-Catalyzed Decarboxylative Allylation of Carbazolones and Indolones: Formal Synthesis of (+)-Kopsihainanine A

(2013) Christopher J. Gartshore et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Expanding Insight into Asymmetric Palladium-Catalyzed Allylic Alkylation of N-Heterocyclic Molecules and Cyclic Ketones

(2013) Nathan B. Bennett et al.   CHEMISTRY-A EUROPEAN JOURNAL

The Construction of All-Carbon Quaternary Stereocenters by Use of Pd-Catalyzed Asymmetric Allylic Alkylation Reactions in Total Synthesis

(2013) Allen Y. Hong et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

One-Pot Anti-Markovnikov Hydroamination of Unactivated Alkenes by Hydrozirconation and Amination

(2013) Alexandra E. Strom et al.   JOURNAL OF ORGANIC CHEMISTRY

Enantioselective Total Synthesis of (−)-Limaspermidine and Formal Synthesis of (−)-1-Acetylaspidoalbidine

(2013) Shao-Xiong Zhang et al.   JOURNAL OF ORGANIC CHEMISTRY

Enantioselective Total Syntheses of Leuconolam–Leuconoxine–Mersicarpine Group Monoterpene Indole Alkaloids

(2013) Zhengren Xu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

A Concise and Versatile Double-Cyclization Strategy for the Highly Stereoselective Synthesis and Arylative Dimerization of Aspidosperma Alkaloids

(2012) Jonathan William Medley et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Total Synthesis of (±)-Kopsihainanine A

(2012) Peng Jing et al.   CHEMISTRY-A EUROPEAN JOURNAL

The Reaction Mechanism of the Enantioselective Tsuji Allylation: Inner-Sphere and Outer-Sphere Pathways, Internal Rearrangements, and Asymmetric C–C Bond Formation

(2012) John A. Keith et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Pd(II)-Catalyzed Regioselective 2-Alkylation of Indoles via a Norbornene-Mediated C–H Activation: Mechanism and Applications

(2012) Lei Jiao et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Application of a Raney-Cobalt-Mediated Tandem Reductive Cyclization Protocol to Total Syntheses of the Aspidosperma Alkaloids (±)-Limaspermidine and (±)-1-Acetylaspidoalbidine

(2012) Shen H. Tan et al.   ORGANIC LETTERS

Enantioselective Decarboxylative Alkylation Reactions: Catalyst Development, Substrate Scope, and Mechanistic Studies

(2011) Douglas C. Behenna et al.   CHEMISTRY-A EUROPEAN JOURNAL

Collective synthesis of natural products by means of organocascade catalysis

(2011) Spencer B. Jones et al.   NATURE

Enantioselective construction of quaternary N-heterocycles by palladium-catalysed decarboxylative allylic alkylation of lactams

(2011) Douglas C. Behenna et al.   Nature Chemistry

Kopsihainanines A and B, two unusual alkaloids from Kopsia hainanensis

(2011) Jia Chen et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Iminium Ion Cascade Reaction in the Total Synthesis of (+)-Vincadifformine

(2011) Ganesh Pandey et al.   ORGANIC LETTERS

Melotenine A, a Cytotoxic Monoterpenoid Indole Alkaloid fromMelodinus tenuicaudatus

(2010) Tao Feng et al.   ORGANIC LETTERS

A Concise Enantioselective Synthesis of (−)-Ranirestat

(2010) Barry M. Trost et al.   ORGANIC LETTERS

Total Synthesis of (±)-Quebrachamine via [3+2] Cycloaddition and Efficient Chloroacetamide Photocyclization

(2009) Barbora Bajtos et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Rhazinilam and Quebrachamine Derivatives from YunnanKopsia arborea

(2009) Yuqiu Wu et al.   JOURNAL OF NATURAL PRODUCTS

Melodinines A−G, Monoterpenoid Indole Alkaloids fromMelodinus henryi

(2009) Tao Feng et al.   JOURNAL OF NATURAL PRODUCTS

Palladium-Catalyzed Decarboxylative Asymmetric Allylic Alkylation of Enol Carbonates

(2009) Barry M. Trost et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Monoterpenoid Indole Alkaloids from the Bark ofAlstonia scholaris

(2009) Tao Feng et al.   PLANTA MEDICA

A Concise Asymmetric Total Synthesis of Aspidophytine

(2008) K. C. Nicolaou et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Pseudo-domino palladium-catalyzed allylic alkylation/Mizoroki–Heck coupling reaction: a key sequence toward (±)-podophyllotoxin

(2007) Francesco Mingoia et al.   TETRAHEDRON LETTERS