β-Escin Effectively Modulates HUVECs Proliferation and Tube Formation

2,5-Dihydroxyacetophenone Induces Apoptosis of Multiple Myeloma Cells by Regulating the MAPK Activation Pathway

(2017) Jeong-Hyeon Ko et al.   MOLECULES

Escin induces caspase-dependent apoptosis and autophagy through the ROS/p38 MAPK signalling pathway in human osteosarcoma cells in vitro and in vivo

(2017) Jian Zhu et al.   Cell Death & Disease

Ephrin-B2/Fc promotes proliferation and migration, and suppresses apoptosis in human umbilical vein endothelial cells

(2017) Li-Chun Zheng et al.   Oncotarget

The positive clinical therapeutically effects of Escin on advanced thyroid cancer

(2017) Jin-Yu Mei et al.   Cancer Medicine

Ginkgolic Acid Inhibits Invasion and Migration and TGF-β-Induced EMT of Lung Cancer Cells Through PI3K/Akt/mTOR Inactivation

(2016) Seung Ho Baek et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Molecular Mechanism for Cellular Response to β-Escin and Its Therapeutic Implications

(2016) Dominik Domanski et al.   PLoS One

Natural products against cancer angiogenesis

(2016) El Bairi Khalid et al.   TUMOR BIOLOGY

Escin Ia suppresses the metastasis of triple-negative breast cancer by inhibiting epithelial-mesenchymal transition via down-regulating LOXL2 expression

(2016) Yuhui Wang et al.   Oncotarget

Escin reduces cell proliferation and induces apoptosis on glioma and lung adenocarcinoma cell lines

(2015) Gülşen Akalin Çiftçi et al.   CYTOTECHNOLOGY

Targeting the PI3K/Akt signaling pathway in gastric carcinoma: A reality for personalized medicine?

(2015) Shikha Satendra Singh   WORLD JOURNAL OF GASTROENTEROLOGY

Thymoquinone overcomes chemoresistance and enhances the anticancer effects of bortezomib through abrogation of NF-κB regulated gene products in multiple myeloma xenograft mouse model

(2015) Kodappully Sivaraman Siveen et al.   Oncotarget

γ-tocotrienol inhibits angiogenesis-dependent growth of human hepatocellular carcinoma through abrogation of AKT/mTOR pathway in an orthotopic mouse model

(2015) Kodappully Sivaraman Siveen et al.   Oncotarget

Antiangiogenesis Strategies Revisited: From Starving Tumors to Alleviating Hypoxia

(2014) Rakesh K. Jain   CANCER CELL

Cytotoxic Effects of Escin on Human Castration-resistant Prostate Cancer Cells Through the Induction of Apoptosis and G2/M Cell Cycle Arrest

(2014) Songzhe Piao et al.   UROLOGY

 -Escin Inhibits NNK-Induced Lung Adenocarcinoma and ALDH1A1 and RhoA/Rock Expression in A/J Mice and Growth of H460 Human Lung Cancer Cells

(2013) J. M. R. Patlolla et al.   Cancer Prevention Research

United States Food and Drug Administration approved oral kinase inhibitors for the treatment of malignancies

(2013) Woondong Jeong et al.   CURRENT PROBLEMS IN CANCER

Anti-angiogenic activity of the flavonoid precursor 4-hydroxychalcone

(2012) Lenka Varinska et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Targeting the MAPK–RAS–RAF signaling pathway in cancer therapy

(2012) Libero Santarpia et al.   EXPERT OPINION ON THERAPEUTIC TARGETS

Escin augments the efficacy of gemcitabine through down-regulation of nuclear factor-κB and nuclear factor-κB-regulated gene products in pancreatic cancer both in vitro and in vivo

(2012) Yong-Wei Wang et al.   JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY

The Apoptotic Effects of Escin in The H-RasTransformed 5RP7 Cell Line

(2012) G. Güney et al.   PHYTOTHERAPY RESEARCH

PI3K/AKT/mTOR Pathway in Angiogenesis

(2011) Jayashree Karar et al.   Frontiers in Molecular Neuroscience

Angiogenesis as a potential target of pharmaconutrients in cancer therapy

(2010) Virginie Granci et al.   CURRENT OPINION IN CLINICAL NUTRITION AND METABOLIC CARE

Escin, a Pentacyclic Triterpene, Chemosensitizes Human Tumor Cells through Inhibition of Nuclear Factor- B Signaling Pathway

(2010) K. B. Harikumar et al.   MOLECULAR PHARMACOLOGY

Anti-obesity Effects of Escins Extracted from the Seeds of Aesculus turbinata BLUME (Hippocastanaceae)

(2008) Jiang-Ning Hu et al.   CHEMICAL & PHARMACEUTICAL BULLETIN

Effect of β-escin sodium on endothelial cells proliferation, migration and apoptosis

(2008) Xu-Hua Wang et al.   VASCULAR PHARMACOLOGY

Pilot Postoperative Ileus Study of Escin in Cancer Patients After Colorectal Surgery

(2008) Qiwei Xie et al.   WORLD JOURNAL OF SURGERY