Kaempferol Induces G2/M Cell Cycle Arrest via Checkpoint Kinase 2 and Promotes Apoptosis via Death Receptors in Human Ovarian Carcinoma A2780/CP70 Cells

Cancer statistics, 2018

(2018) Rebecca L. Siegel et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Kaempferol Sensitizes Human Ovarian Cancer Cells-OVCAR-3 and SKOV-3 to Tumor Necrosis Factor-Related Apoptosis-Inducing Ligand (TRAIL)-Induced Apoptosis via JNK/ERK-CHOP Pathway and Up-Regulation of Death Receptors 4 and 5

(2017) Yingmei Zhao et al.   MEDICAL SCIENCE MONITOR

Kaempferol induces ATM/p53-mediated death receptor and mitochondrial apoptosis in human umbilical vein endothelial cells

(2016) CHIU-FANG LEE et al.   INTERNATIONAL JOURNAL OF ONCOLOGY

Kaempferol Activates G2-Checkpoint of the Cell Cycle Resulting in G2-Arrest and Mitochondria-Dependent Apoptosis in Human Acute Leukemia Jurkat T Cells

(2016) Ki Yun Kim et al.   JOURNAL OF MICROBIOLOGY AND BIOTECHNOLOGY

Cancer stem-like cells of ovarian clear cell carcinoma are enriched in the ALDH-high population associated with an accelerated scavenging system in reactive oxygen species

(2015) T. Mizuno et al.   GYNECOLOGIC ONCOLOGY

Theaflavin-3, 3′-digallate decreases human ovarian carcinoma OVCAR-3 cell-induced angiogenesis via Akt and Notch-1 pathways, not via MAPK pathways

(2015) YING GAO et al.   INTERNATIONAL JOURNAL OF ONCOLOGY

Apple polyphenol induces cell apoptosis, cell cycle arrest at G2/M phase, and mitotic catastrophe in human bladder transitional carcinoma cells

(2015) Yu-Lin Kao et al.   Journal of Functional Foods

Suppression of death receptor 5 enhances cancer cell invasion and metastasis through activation of caspase-8/TRAF2-mediated signaling

(2015) You-Take Oh et al.   Oncotarget

Mechanisms Underlying Apoptosis-Inducing Effects of Kaempferol in HT-29 Human Colon Cancer Cells

(2014) Hyun Lee et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

CHK2 kinase in the DNA damage response and beyond

(2014) L. Zannini et al.   Journal of Molecular Cell Biology

Flavonoids as prospective compounds for anti-cancer therapy

(2013) Divyashree Ravishankar et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Dihydromyricetin suppresses the proliferation of hepatocellular carcinoma cells by inducing G2/M arrest through the Chk1/Chk2/Cdc25C pathway

(2013) HAILI HUANG et al.   ONCOLOGY REPORTS

Proapoptotic Activation of Death Receptor 5 on Tumor Endothelial Cells Disrupts the Vasculature and Reduces Tumor Growth

(2012) Nicholas S. Wilson et al.   CANCER CELL

Eupatilin, a dietary flavonoid, induces G2/M cell cycle arrest in human endometrial cancer cells

(2011) Jung-Hoon Cho et al.   FOOD AND CHEMICAL TOXICOLOGY

Kaempferol induces apoptosis in ovarian cancer cells through activating p53 in the intrinsic pathway

(2011) Haitao Luo et al.   FOOD CHEMISTRY

Kaempferol inhibits VEGF expression and in vitro angiogenesis through a novel ERK-NFκB-cMyc-p21 pathway

(2011) Haitao Luo et al.   FOOD CHEMISTRY

A Review on the Dietary Flavonoid Kaempferol

(2011) J. M. Calderon-Montano et al.   MINI-REVIEWS IN MEDICINAL CHEMISTRY

A Phase I Safety and Pharmacokinetic Study of the Death Receptor 5 Agonistic Antibody PRO95780 in Patients with Advanced Malignancies

(2010) D. R. Camidge et al.   CLINICAL CANCER RESEARCH

Tumor Suppressor CHK2: Regulator of DNA Damage Response and Mediator of Chromosomal Stability

(2010) A. Stolz et al.   CLINICAL CANCER RESEARCH

Life and death by death receptors

(2009) Maria Eugenia Guicciardi et al.   FASEB JOURNAL

Tricetin, a Dietary Flavonoid, Inhibits Proliferation of Human Breast Adenocarcinoma MCF-7 Cells by Blocking Cell Cycle Progression and Inducing Apoptosis

(2009) Ya-Ling Hsu et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Didymin, a dietary flavonoid glycoside from citrus fruits, induces Fas-mediated apoptotic pathway in human non-small-cell lung cancer cells in vitro and in vivo

(2009) Jen-Yu Hung et al.   LUNG CANCER

Kaempferol sensitizes colon cancer cells to TRAIL-induced apoptosis

(2008) Tatsushi Yoshida et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Hepatocyte growth factor enhances death receptor-induced apoptosis by up-regulating DR5

(2008) Yang Li et al.   BMC CANCER

Curcumin sensitizes TRAIL-resistant xenografts: molecular mechanisms of apoptosis, metastasis and angiogenesis

(2008) Sharmila Shankar et al.   Molecular Cancer