Mesencephalic Astrocyte-Derived Neurotrophic Factor (MANF) Elevates Stimulus-Evoked Release of Dopamine in Freely-Moving Rats

Unconventional neurotrophic factors CDNF and MANF: Structure, physiological functions and therapeutic potential

(2017) Maria Lindahl et al.   NEUROBIOLOGY OF DISEASE

Parkinson disease

(2017) Werner Poewe et al.   Nature Reviews Disease Primers

Brain delivery of microencapsulated GDNF induces functional and structural recovery in parkinsonian monkeys

(2016) Elisa Garbayo et al.   BIOMATERIALS

Comparative Analysis of the Effects of Neurotrophic Factors CDNF and GDNF in a Nonhuman Primate Model of Parkinson’s Disease

(2016) Enrique Garea-Rodríguez et al.   PLoS One

Therapeutic potential of the endoplasmic reticulum located and secreted CDNF/MANF family of neurotrophic factors in Parkinson's disease

(2015) Merja H. Voutilainen et al.   FEBS LETTERS

Parkinson's disease

(2015) Lorraine V Kalia et al.   LANCET

Evidence for a link between tail biting and central monoamine metabolism in pigs (Sus scrofa domestica)

(2015) Anna Valros et al.   PHYSIOLOGY & BEHAVIOR

GDNF Overexpression from the Native Locus Reveals its Role in the Nigrostriatal Dopaminergic System Function

(2015) Anmol Kumar et al.   PLoS Genetics

Mesencephalic Astrocyte-Derived Neurotrophic Factor Is Involved in Inflammation by Negatively Regulating the NF-κB Pathway

(2015) Lijian Chen et al.   Scientific Reports

Heterogeneity of dopamine neuron activity across traits and states

(2014) M. Marinelli et al.   NEUROSCIENCE

Epistasis between polymorphisms in COMT, ESR1, and GCH1 influences COMT enzyme activity and pain

(2014) Shad B. Smith et al.   PAIN

Overexpression of conserved dopamine neurotrophic factor (CDNF) in astrocytes alleviates endoplasmic reticulum stress-induced cell damage and inflammatory cytokine secretion

(2013) Lei Cheng et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Mesencephalic Astrocyte-Derived Neurotrophic Factor Inhibits Oxygen–Glucose Deprivation-Induced Cell Damage and Inflammation by Suppressing Endoplasmic Reticulum Stress in Rat Primary Astrocytes

(2013) Hua Zhao et al.   JOURNAL OF MOLECULAR NEUROSCIENCE

Gene therapy with AAV2-CDNF provides functional benefits in a rat model of Parkinson's disease

(2013) Susanne Bäck et al.   Brain and Behavior

A Transient Inhibition and Permanent Lack of Catechol-O-Methyltransferase have Minor Effects on Feeding Pattern of Female Rodents

(2011) Nadia Schendzielorz et al.   BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY

CDNF Protects the Nigrostriatal Dopamine System and Promotes Recovery after MPTP Treatment in Mice

(2011) Mikko Airavaara et al.   CELL TRANSPLANTATION

The in vivo neurochemistry of the brain during general anesthesia

(2011) Christian P. Müller et al.   JOURNAL OF NEUROCHEMISTRY

How Addictive Drugs Disrupt Presynaptic Dopamine Neurotransmission

(2011) David Sulzer   NEURON

Novel CDNF/MANF family of neurotrophic factors

(2010) Päivi Lindholm et al.   Developmental Neurobiology

Chronic infusion of CDNF prevents 6-OHDA-induced deficits in a rat model of Parkinson's disease

(2010) Merja H. Voutilainen et al.   EXPERIMENTAL NEUROLOGY

Mesencephalic Astrocyte-derived Neurotrophic Factor (MANF) Has a Unique Mechanism to Rescue Apoptotic Neurons

(2010) Maarit Hellman et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Estimating Extracellular Concentrations of Dopamine and 3,4-Dihydroxyphenylacetic Acid in Nucleus Accumbens and Striatum Using Microdialysis: Relationships Between In Vitro and In Vivo Recoveries

(2010) S. D. Glick et al.   JOURNAL OF NEUROCHEMISTRY

Quantitative role of COMT in dopamine clearance in the prefrontal cortex of freely moving mice

(2010) Mikko Käenmäki et al.   JOURNAL OF NEUROCHEMISTRY

Neurturin Effects on Nigrostriatal Dopamine Release and Content: Comparison with GDNF

(2010) Wayne A. Cass et al.   NEUROCHEMICAL RESEARCH

Pharmacokinetics and bioactivity of glial cell line-derived factor (GDNF) and neurturin (NTN) infused into the rat brain

(2010) Piotr Hadaczek et al.   NEUROPHARMACOLOGY

Repairing the parkinsonian brain with neurotrophic factors

(2010) Liviu Aron et al.   TRENDS IN NEUROSCIENCES

Bilateral effects of unilateral GDNF administration on dopamine- and GABA-regulating proteins in the rat nigrostriatal system

(2009) Michael F. Salvatore et al.   EXPERIMENTAL NEUROLOGY

Mesencephalic Astrocyte-Derived Neurotrophic Factor Is Neurorestorative in Rat Model of Parkinson's Disease

(2009) M. H. Voutilainen et al.   JOURNAL OF NEUROSCIENCE

The structure of the conserved neurotrophic factors MANF and CDNF explains why they are bifunctional

(2009) Vimal Parkash et al.   PROTEIN ENGINEERING DESIGN & SELECTION

Mesencephalic Astrocyte-Derived Neurotrophic Factor Is an Ischemia-Inducible Secreted Endoplasmic Reticulum Stress Response Protein in the Heart

(2008) Archana Tadimalla et al.   CIRCULATION RESEARCH

Signalling mechanisms underlying development and maintenance of dopamine neurons

(2008) Jaan-Olle Andressoo et al.   CURRENT OPINION IN NEUROBIOLOGY

Armet, a UPR-upregulated protein, inhibits cell proliferation and ER stress-induced cell death

(2008) A APOSTOLOU et al.   EXPERIMENTAL CELL RESEARCH

Characterization of the striatal dopaminergic neurotransmission in MEN2B mice with elevated cerebral tissue dopamine

(2008) Jelena Mijatovic et al.   JOURNAL OF NEUROCHEMISTRY

Depolarization-stimulated catecholamine biosynthesis: involvement of protein kinases and tyrosine hydroxylase phosphorylation sites in situ

(2003) Michael F. Salvatore et al.   JOURNAL OF NEUROCHEMISTRY