Inhibition of Peroxynitrite-Induced Mitophagy Activation Attenuates Cerebral Ischemia-Reperfusion Injury

Reactive nitrogen species as therapeutic targets for autophagy: implication for ischemic stroke

(2017) Jinghan Feng et al.   EXPERT OPINION ON THERAPEUTIC TARGETS

Mitochondrial Dynamics: Coupling Mitochondrial Fitness with Healthy Aging

(2017) David Sebastián et al.   TRENDS IN MOLECULAR MEDICINE

Drp-1, a potential therapeutic target for brain ischaemic stroke

(2016) W Zuo et al.   BRITISH JOURNAL OF PHARMACOLOGY

Melatonin attenuates traumatic brain injury-induced inflammation: a possible role for mitophagy

(2016) Chao Lin et al.   JOURNAL OF PINEAL RESEARCH

Evidence for the recruitment of autophagic vesicles in human brain after stroke

(2016) Tony Frugier et al.   NEUROCHEMISTRY INTERNATIONAL

The critical roles of mitophagy in cerebral ischemia

(2016) Yan-Cheng Tang et al.   Protein & Cell

Peroxynitrite Decomposition Catalyst Reduces Delayed Thrombolysis-induced Hemorrhagic Transformation in Ischemia-reperfused Rat Brains

(2015) Han-Sen Chen et al.   CNS Neuroscience & Therapeutics

Low concentrations of chloroquine and 3-methyladenine suppress the viability of retinoblastoma cells synergistically with vincristine independent of autophagy inhibition

(2015) Xiao-Yu Zheng et al.   GRAEFES ARCHIVE FOR CLINICAL AND EXPERIMENTAL OPHTHALMOLOGY

Autophagy biomarkers in CSF correlates with infarct size, clinical severity and neurological outcome in AIS patients

(2015) Honghong Li et al.   Journal of Translational Medicine

Suppression of mitochondrial fission in experimental cerebral ischemia: The potential neuroprotective target of p38 MAPK inhibition

(2015) Xue-mei Zhang et al.   NEUROCHEMISTRY INTERNATIONAL

Momordica charantia polysaccharides could protect against cerebral ischemia/reperfusion injury through inhibiting oxidative stress mediated c-Jun N-terminal kinase 3 signaling pathway

(2015) Juanjuan Gong et al.   NEUROPHARMACOLOGY

Therapeutic targeting of autophagy in cancer. Part II: Pharmacological modulation of treatment-induced autophagy

(2015) Anika Nagelkerke et al.   SEMINARS IN CANCER BIOLOGY

Regulation of mitophagy in ischemic brain injury

(2015) Yang Yuan et al.   Neuroscience Bulletin

Autophagy in neonatal hypoxia ischemic brain is associated with oxidative stress

(2015) Qing Lu et al.   Redox Biology

Rapamycin attenuates mitochondrial dysfunction via activation of mitophagy in experimental ischemic stroke

(2014) Qiang Li et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Functional interplay between Parkin and Drp1 in mitochondrial fission and clearance

(2014) Lori Buhlman et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Blood–brain barrier disruption induced by hemoglobin in vivo: Involvement of up-regulation of nitric oxide synthase and peroxynitrite formation

(2014) Rui Ding et al.   BRAIN RESEARCH

BNIP3 Interacting with LC3 Triggers Excessive Mitophagy in Delayed Neuronal Death in Stroke

(2014) Ruo-Yang Shi et al.   CNS Neuroscience & Therapeutics

Autophagy: a double-edged sword for neuronal survival after cerebral ischemia

(2014) Kangyong Liu et al.   Neural Regeneration Research

Mitochondria autophagy is induced after hypoxic/ischemic stress in a Drp1 dependent manner: The role of inhibition of Drp1 in ischemic brain damage

(2014) Wei Zuo et al.   NEUROPHARMACOLOGY

Modulation of Mitochondrial Function and Autophagy Mediates Carnosine Neuroprotection Against Ischemic Brain Damage

(2014) Seung-Hoon Baek et al.   STROKE

Recanalization and Reperfusion Therapies of Acute Ischemic Stroke: What have We Learned, What are the Major Research Questions, and Where are We Headed?

(2014) Meritxell Gomis et al.   Frontiers in Neurology

Tools and techniques to measure mitophagy using fluorescence microscopy

(2013) Nick J Dolman et al.   Autophagy

Crosstalk between apoptosis, necrosis and autophagy

(2013) Vassiliki Nikoletopoulou et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Historical landmarks of autophagy research

(2013) Yoshinori Ohsumi   CELL RESEARCH

The role of cell signalling in the crosstalk between autophagy and apoptosis

(2013) Laurence A. Booth et al.   CELLULAR SIGNALLING

Baicalin can scavenge peroxynitrite and ameliorate endogenous peroxynitrite-mediated neurotoxicity in cerebral ischemia-reperfusion injury

(2013) Mingjing Xu et al.   JOURNAL OF ETHNOPHARMACOLOGY

Emerging regulation and functions of autophagy

(2013) Patricia Boya et al.   NATURE CELL BIOLOGY

Mitophagy in Ischaemia/Reperfusion Induced Cerebral Injury

(2013) Kangyong Liu et al.   NEUROCHEMICAL RESEARCH

Neuroprotective effects of lactate in brain ischemia: Dependence on anesthetic drugs

(2013) Tobias Horn et al.   NEUROCHEMISTRY INTERNATIONAL

Physiological and Pathological Significance of Dynamin-Related Protein 1 (Drp1)-Dependent Mitochondrial Fission in the Nervous System

(2013) Bongki Cho et al.   Experimental Neurobiology

Targeting reactive nitrogen species: a promising therapeutic strategy for cerebral ischemia-reperfusion injury

(2012) Xing-miao Chen et al.   ACTA PHARMACOLOGICA SINICA

The pathways of mitophagy for quality control and clearance of mitochondria

(2012) G Ashrafi et al.   CELL DEATH AND DIFFERENTIATION

A Double-Edged Sword with Therapeutic Potential: An Updated Role of Autophagy in Ischemic Cerebral Injury

(2012) Kai Wei et al.   CNS Neuroscience & Therapeutics

Autophagosomal Membrane Serves as Platform for Intracellular Death-inducing Signaling Complex (iDISC)-mediated Caspase-8 Activation and Apoptosis

(2012) Megan M. Young et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Plasma 3-nitrotyrosine estimates the reperfusion-induced cerebrovascular stress, whereas matrix metalloproteinases mainly reflect plasma activity: a study in patients treated with thrombolysis or endovascular recanalization

(2012) Demet Funda Bas et al.   JOURNAL OF NEUROCHEMISTRY

Effect of anesthesia and cerebral blood flow on neuronal injury in a rat middle cerebral artery occlusion (MCAO) model

(2012) C. Bleilevens et al.   EXPERIMENTAL BRAIN RESEARCH

In vivo protein tyrosine nitration in Arabidopsis thaliana

(2011) Jorge Lozano-Juste et al.   JOURNAL OF EXPERIMENTAL BOTANY

The Autophagy Protein Atg12 Associates with Antiapoptotic Bcl-2 Family Members to Promote Mitochondrial Apoptosis

(2011) Assaf D. Rubinstein et al.   MOLECULAR CELL

In vivo imaging of autophagy in a mouse stroke model

(2010) FengFeng Tian et al.   Autophagy

What are the sources of hydrogen peroxide production by heart mitochondria?

(2010) Vera G. Grivennikova et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

Age-related accumulation of 3-nitrotyrosine and nitro-A2E in human Bruch's membrane

(2010) L.S. Murdaugh et al.   EXPERIMENTAL EYE RESEARCH

S-Nitrosylation of Drp1 links excessive mitochondrial fission to neuronal injury in neurodegeneration

(2010) Tomohiro Nakamura et al.   MITOCHONDRION

Increased Protein Nitration in Mitochondrial Diseases: Evidence for Vessel Wall Involvement

(2010) Gaetano Vattemi et al.   MOLECULAR & CELLULAR PROTEOMICS

Recanalization therapy for acute ischemic stroke, part 1: surgical embolectomy and chemical thrombolysis

(2010) Saeed Ansari et al.   NEUROSURGICAL REVIEW

Chemical Biology of Peroxynitrite: Kinetics, Diffusion, and Radicals

(2009) Gerardo Ferrer-Sueta et al.   ACS Chemical Biology

Biochemical and cellular toxicology of peroxynitrite: implications in cell death and autoimmune phenomenon

(2009) Rizwan Ahmad et al.   IMMUNOPHARMACOLOGY AND IMMUNOTOXICOLOGY

S-Nitrosylation of Drp1 Mediates β-Amyloid-Related Mitochondrial Fission and Neuronal Injury

(2009) Dong-Hyung Cho et al.   SCIENCE

The ADP and ATP transport in mitochondria and its carrier

(2008) Martin Klingenberg   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Proteomic analysis of protein tyrosine nitration after ischemia reperfusion injury: Mitochondria as the major target

(2008) Bin Liu et al.   BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS