Targeting the Brain with a Neuroprotective Omega-3 Fatty Acid to Enhance Neurogenesis in Hypoxic Condition in Culture

Protectin DX ameliorates palmitate- or high-fat diet-induced insulin resistance and inflammation through an AMPK-PPARα-dependent pathway in mice

(2017) Tae Woo Jung et al.   Scientific Reports

Dietary docosahexaenoic acid (DHA) as lysophosphatidylcholine, but not as free acid, enriches brain DHA and improves memory in adult mice

(2017) Dhavamani Sugasini et al.   Scientific Reports

Mechanisms of DHA transport to the brain and potential therapy to neurodegenerative diseases

(2016) Amanda Lo Van et al.   BIOCHIMIE

Structural Insights into the Transport Mechanism of the Human Sodium-dependent Lysophosphatidylcholine Transporter MFSD2A

(2016) Debra Q. Y. Quek et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Urinary biomarkers of oxidative and nitrosative stress and the risk for incident stroke: A nested case–control study from a community-based cohort

(2015) Hung-Ju Lin et al.   INTERNATIONAL JOURNAL OF CARDIOLOGY

12/15-Lipoxygenase metabolites of arachidonic acid activate PPARγ: a possible neuroprotective effect in ischemic brain

(2015) Li Sun et al.   JOURNAL OF LIPID RESEARCH

Efficient Docosahexaenoic Acid Uptake by the Brain from a Structured Phospholipid

(2015) Mayssa Hachem et al.   MOLECULAR NEUROBIOLOGY

Pathophysiological Roles of Cyclooxygenases and Prostaglandins in the Central Nervous System

(2015) Tatsurou Yagami et al.   MOLECULAR NEUROBIOLOGY

Biological properties of a DHA-containing structured phospholipid (AceDoPC) to target the brain

(2015) M. Lagarde et al.   PROSTAGLANDINS LEUKOTRIENES AND ESSENTIAL FATTY ACIDS

Maternal dietary imbalance between omega-6 and omega-3 polyunsaturated fatty acids impairs neocortical development via epoxy metabolites

(2015) Nobuyuki Sakayori et al.   STEM CELLS

Omega-3 Fatty Acids Protect the Brain against Ischemic Injury by Activating Nrf2 and Upregulating Heme Oxygenase 1

(2014) M. Zhang et al.   JOURNAL OF NEUROSCIENCE

Mfsd2a is a transporter for the essential omega-3 fatty acid docosahexaenoic acid

(2014) Long N. Nguyen et al.   NATURE

Resolvins, Specialized Proresolving Lipid Mediators, and Their Potential Roles in Metabolic Diseases

(2013) Matthew Spite et al.   Cell Metabolism

Protectin DX, a Double Lipoxygenase Product of DHA, Inhibits Both ROS Production in Human Neutrophils and Cyclooxygenase Activities

(2013) Miao Liu et al.   LIPIDS

Omega-3 Polyunsaturated Fatty Acids Enhance Neuronal Differentiation in Cultured Rat Neural Stem Cells

(2013) Masanori Katakura et al.   Stem Cells International

Brain-Targeting Form of Docosahexaenoic Acid for Experimental Stroke Treatment: MRI Evaluation and Anti-Oxidant Impact

(2011) Fabien Chauveau et al.   CURRENT NEUROVASCULAR RESEARCH

Distinctive effects of arachidonic acid and docosahexaenoic acid on neural stem /progenitor cells

(2011) Nobuyuki Sakayori et al.   GENES TO CELLS

DHA inhibits ER Ca2+ release and ER stress in astrocytes following in vitro ischemia

(2011) Gulnaz Begum et al.   JOURNAL OF NEUROCHEMISTRY

Specialized pro-resolving lipid mediators in the inflammatory response: An update

(2010) Gerard Bannenberg et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Poxytrins, a class of oxygenated products from polyunsaturated fatty acids, potently inhibit blood platelet aggregation

(2010) Ping Chen et al.   FASEB JOURNAL

Lineage analysis of newly generated neurons in organotypic culture of rat hippocampus

(2010) Jun Yokose et al.   NEUROSCIENCE RESEARCH

Resolvins and protectins: Natural pharmacophores for resolution biology

(2010) Bruce D. Levy   PROSTAGLANDINS LEUKOTRIENES AND ESSENTIAL FATTY ACIDS

Effects of docosahexaenoic acid on in vitro amyloid beta peptide 25–35 fibrillation

(2009) Michio Hashimoto et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Full characterization of PDX, a neuroprotectin/protectin D1 isomer, which inhibits blood platelet aggregation

(2009) P. Chen et al.   FEBS LETTERS

Effect of Dietary Docosahexaenoic Acid Connecting Phospholipids on the Lipid Peroxidation of the Brain in Mice

(2009) Seiichi HIRATSUKA et al.   JOURNAL OF NUTRITIONAL SCIENCE AND VITAMINOLOGY

Docosahexaenoic acid promotes neuronal differentiation by regulating basic helix–loop–helix transcription factors and cell cycle in neural stem cells

(2009) M. Katakura et al.   NEUROSCIENCE

Improved spatial learning performance of fat-1 mice is associated with enhanced neurogenesis and neuritogenesis by docosahexaenoic acid

(2009) C. He et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

α-Linolenic acid supplementation and conversion to n-3 long-chain polyunsaturated fatty acids in humans

(2009) J. Thomas Brenna et al.   PROSTAGLANDINS LEUKOTRIENES AND ESSENTIAL FATTY ACIDS

Robust Docosahexaenoic Acid–Mediated Neuroprotection in a Rat Model of Transient, Focal Cerebral Ischemia

(2009) Ludmila Belayev et al.   STROKE

Protective effect of docosahexaenoic acid against brain injury in ischemic rats

(2008) Hung-Chuan Pan et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

Spatiotemporal Recapitulation of Central Nervous System Development by Murine Embryonic Stem Cell-Derived Neural Stem/Progenitor Cells

(2008) Yohei Okada et al.   STEM CELLS