Role of Nitric Oxide and Hydrogen Sulfide in Ischemic Stroke and the Emergent Epigenetic Underpinnings

Gasotransmitter hydrogen sulfide signaling in neuronal health and disease

(2018) Bindu D. Paul et al.   BIOCHEMICAL PHARMACOLOGY

Nitric Oxide and Mitochondrial Function in Neurological Diseases

(2018) Mehdi Ghasemi et al.   NEUROSCIENCE

The role of hypernitrosylation in the pathogenesis and pathophysiology of neuroprogressive diseases

(2018) Gerwyn Morris et al.   NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS

Nitric oxide-mediated posttranslational modifications control neurotransmitter release by modulating complexin farnesylation and enhancing its clamping ability

(2018) Susan W. Robinson et al.   PLOS BIOLOGY

Nitric oxide-mediated pathways and its role in the degenerative diseases

(2017) Yanling Yin   Frontiers in Bioscience-Landmark

Hydrogen sulfide modulates eukaryotic translation initiation factor 2α (eIF2α) phosphorylation status in the integrated stress-response pathway

(2017) Vinita Yadav et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Opening a New Time Window for Treatment of Stroke by Targeting HDAC2

(2017) Yu-Hui Lin et al.   JOURNAL OF NEUROSCIENCE

Interplay between mitochondrial metabolism and oxidative stress in ischemic stroke: An epigenetic connection

(2017) Parimala Narne et al.   MOLECULAR AND CELLULAR NEUROSCIENCE

Nitrosothiol formation and S-nitrosation signaling through nitric oxide synthases

(2017) Sarah L. Wynia-Smith et al.   NITRIC OXIDE-BIOLOGY AND CHEMISTRY

Epigenetics: The third pillar of nitric oxide signaling

(2017) Samantha Socco et al.   PHARMACOLOGICAL RESEARCH

Cystathionine-β-synthase-derived hydrogen sulfide is required for amygdalar long-term potentiation and cued fear memory in rats

(2017) Hai-Bo Chen et al.   PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR

Poly(ADP-ribose)polymerase-1 hyperactivation in neurodegenerative diseases: The death knell tolls for neurons

(2017) Parimala Narne et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Sodium hydrosulfide attenuates cerebral ischemia/reperfusion injury by suppressing overactivated autophagy in rats

(2017) Wen-Wu Jiang et al.   FEBS Open Bio

SIRT3 Mediates the Antioxidant Effect of Hydrogen Sulfide in Endothelial Cells

(2016) Liping Xie et al.   ANTIOXIDANTS & REDOX SIGNALING

S-adenosylhomocysteine induces inflammation through NFkB: A possible role for EZH2 in endothelial cell activation

(2016) Madalena Barroso et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Atorvastatin Attenuates Ischemia/Reperfusion-Induced Hippocampal Neurons Injury Via Akt-nNOS-JNK Signaling Pathway

(2016) Sen Shao et al.   CELLULAR AND MOLECULAR NEUROBIOLOGY

Sodium Sulfide, a Hydrogen Sulfide-Releasing Molecule, Attenuates Acute Cerebral Ischemia in Rats

(2016) Hao-Qiang Shi et al.   CNS Neuroscience & Therapeutics

Hydrogen Sulfide Induces Keap1 S-sulfhydration and Suppresses Diabetes-Accelerated Atherosclerosis via Nrf2 Activation

(2016) Liping Xie et al.   DIABETES

Epigenetic suppression of iNOS expression in human endothelial cells: A potential role of Ezh2-mediated H3K27me3

(2016) Henryk Dreger et al.   GENOMICS

Involvement of exogenous H2S in recovery of cardioprotection from ischemic post-conditioning via increase of autophagy in the aged hearts

(2016) Junting Chen et al.   INTERNATIONAL JOURNAL OF CARDIOLOGY

Mechanism of Sirt1 NAD+-dependent Protein Deacetylase Inhibition by CysteineS-Nitrosation

(2016) Kelsey S. Kalous et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

HDAC9 exacerbates endothelial injury in cerebral ischaemia/reperfusion injury

(2016) Weichen Shi et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Neuronal deficiency of HIF prolyl 4-hydroxylase 2 in mice improves ischemic stroke recovery in an HIF dependent manner

(2016) Lexiao Li et al.   NEUROBIOLOGY OF DISEASE

Nitric oxide, the new architect of epigenetic landscapes

(2016) Divya Vasudevan et al.   NITRIC OXIDE-BIOLOGY AND CHEMISTRY

Hydrogen Sulfide Attenuates Tissue Plasminogen Activator-Induced Cerebral Hemorrhage Following Experimental Stroke

(2016) Hui Liu et al.   Translational Stroke Research

“Zipped Synthesis” by Cross-Metathesis Provides a Cystathionine β-Synthase Inhibitor that Attenuates Cellular H2S Levels and Reduces Neuronal Infarction in a Rat Ischemic Stroke Model

(2016) Christopher D. McCune et al.   ACS Central Science

Mitochondria-targeted esculetin alleviates mitochondrial dysfunction by AMPK-mediated nitric oxide and SIRT3 regulation in endothelial cells: potential implications in atherosclerosis

(2016) Santosh Karnewar et al.   Scientific Reports

Purinergic glio-endothelial coupling during neuronal activity: role of P2Y1 receptors and eNOS in functional hyperemia in the mouse somatosensory cortex

(2015) Peter Toth et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Modes of Physiologic H2S Signaling in the Brain and Peripheral Tissues

(2015) Bindu D. Paul et al.   ANTIOXIDANTS & REDOX SIGNALING

Signaling Molecules: Hydrogen Sulfide and Polysulfide

(2015) Hideo Kimura   ANTIOXIDANTS & REDOX SIGNALING

Epigenetics in the Vascular EndotheliumSignificance

(2015) Matthew S. Yan et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Cystathionine β-Synthase Inhibition Is a Potential Therapeutic Approach to Treatment of Ischemic Injury

(2015) Su Jing Chan et al.   ASN Neuro

Endogenous S-sulfhydration of PTEN helps protect against modification by nitric oxide

(2015) Kazuki Ohno et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Nitric Oxide Regulates Gene Expression in Cancers by Controlling Histone Posttranslational Modifications

(2015) D. Vasudevan et al.   CANCER RESEARCH

ROS-Dependent Neuroprotective Effects of NaHS in Ischemia Brain Injury Involves the PARP/AIF Pathway

(2015) Qian Yu et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

The role of the nitric oxide pathway in brain injury and its treatment — From bench to bedside

(2015) P.S. Garry et al.   EXPERIMENTAL NEUROLOGY

Hydrogen sulfide attenuates cytokine production through the modulation of chromatin remodeling

(2015) ESTER C.S. RIOS et al.   INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE

Selective Irreversible Inhibition of Neuronal and Inducible Nitric-oxide Synthase in the Combined Presence of Hydrogen Sulfide and Nitric Oxide

(2015) Christian L. Heine et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

S-Nitrosylation of Bcl-2 Negatively Affects Autophagy in Lung Epithelial Cells

(2015) Clayton Wright et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Sirtuin 6 Is Essential for Sodium Sulfide-mediated Cytoprotective Effect in Ischemia/Reperfusion–Stimulated Brain Endothelial Cells

(2015) Youyang Hu et al.   Journal of Stroke & Cerebrovascular Diseases

Effect of the Inhibition of Hydrogen Sulfide Synthesis on Ischemic Injury and Oxidative Stress Biomarkers in a Transient Model of Focal Cerebral Ischemia in Rats

(2015) Maryam Hadadha et al.   Journal of Stroke & Cerebrovascular Diseases

EZH2 Modulates Angiogenesis In Vitro and in a Mouse Model of Limb Ischemia

(2015) Tijana Mitić et al.   MOLECULAR THERAPY

Biogenesis of reactive sulfur species for signaling by hydrogen sulfide oxidation pathways

(2015) Tatiana V Mishanina et al.   Nature Chemical Biology

The role of H2S bioavailability in endothelial dysfunction

(2015) Rui Wang et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Promoting endothelial function by S-nitrosoglutathione through the HIF-1α/VEGF pathway stimulates neurorepair and functional recovery following experimental stroke in rats

(2015) Mushfiquddin Khan et al.   Drug Design Development and Therapy

Regulation of the unfolded protein response via S-nitrosylation of sensors of endoplasmic reticulum stress

(2015) Ryosuke Nakato et al.   Scientific Reports

Sirtuin 6 Is Essential for Sodium Sulfide-mediated Cytoprotective Effect in Ischemia/Reperfusion–Stimulated Brain Endothelial Cells

(2015) Youyang Hu et al.   Journal of Stroke & Cerebrovascular Diseases

Effect of the Inhibition of Hydrogen Sulfide Synthesis on Ischemic Injury and Oxidative Stress Biomarkers in a Transient Model of Focal Cerebral Ischemia in Rats

(2015) Maryam Hadadha et al.   Journal of Stroke & Cerebrovascular Diseases

Histone deacetylase 1 reduces NO production in endothelial cells via lysine deacetylation of NO synthase 3

(2014) Kelly A. Hyndman et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Unsuspected task for an old team: Succinate, fumarate and other Krebs cycle acids in metabolic remodeling

(2014) Paule Bénit et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

Novel role of silent information regulator 1 in acute endothelial cell oxidative stress injury

(2014) Yue Li et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

S-nitrosation and neuronal plasticity

(2014) A I Santos et al.   BRITISH JOURNAL OF PHARMACOLOGY

Respiratory Substrates Regulate S-Nitrosylation of Mitochondrial Proteins through a Thiol-Dependent Pathway

(2014) Allen H. K. Chang et al.   CHEMICAL RESEARCH IN TOXICOLOGY

A Redox-resistant Sirtuin-1 Mutant Protects against Hepatic Metabolic and Oxidant Stress

(2014) Di Shao et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Hydrogen Sulfide Epigenetically Attenuates Homocysteine-Induced Mitochondrial Toxicity Mediated Through NMDA Receptor in Mouse Brain Endothelial (bEnd3) Cells

(2014) Pradip K. Kamat et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Inducible Nitric Oxide Synthase in Neutrophils and Endothelium Contributes to Ischemic Brain Injury in Mice

(2014) Lidia Garcia-Bonilla et al.   JOURNAL OF IMMUNOLOGY

Hydrogen Sulfide Protects the Brain Against Ischemic Reperfusion Injury in a Transient Model of Focal Cerebral Ischemia

(2014) Sevda Gheibi et al.   JOURNAL OF MOLECULAR NEUROSCIENCE

Hydrogen sulfide protects blood-brain barrier integrity following cerebral ischemia

(2014) Yali Wang et al.   JOURNAL OF NEUROCHEMISTRY

Endothelial Dysfunction Abrogates the Efficacy of Normobaric Hyperoxia in Stroke

(2014) H. K. Shin et al.   JOURNAL OF NEUROSCIENCE

Interaction of nNOS with PSD-95 Negatively Controls Regenerative Repair after Stroke

(2014) C.-X. Luo et al.   JOURNAL OF NEUROSCIENCE

Hydrogen sulfide treatment induces angiogenesis after cerebral ischemia

(2014) Hyunduk Jang et al.   JOURNAL OF NEUROSCIENCE RESEARCH

Cytokine-Induced GAPDH Sulfhydration Affects PSD95 Degradation and Memory

(2014) Sajad Mir et al.   MOLECULAR CELL

Ischaemic accumulation of succinate controls reperfusion injury through mitochondrial ROS

(2014) Edward T. Chouchani et al.   NATURE

Inflammatory stimuli induce inhibitory S-nitrosylation of the deacetylase SIRT1 to increase acetylation and activation of p53 and p65

(2014) S. Shinozaki et al.   Science Signaling

The coordination of S-sulfhydration, S-nitrosylation, and phosphorylation of endothelial nitric oxide synthase by hydrogen sulfide

(2014) Z. Altaany et al.   Science Signaling

Silent Information Regulator 2 Homolog 1 Counters Cerebral Hypoperfusion Injury by Deacetylating Endothelial Nitric Oxide Synthase

(2014) Yorito Hattori et al.   STROKE

S-Nitrosylation-Mediated Redox Transcriptional Switch Modulates Neurogenesis and Neuronal Cell Death

(2014) Shu-ichi Okamoto et al.   Cell Reports

Redox Modulation of Endothelial Nitric Oxide Synthase by Glutaredoxin-1 through Reversible Oxidative Post-Translational Modification

(2013) Chun-An Chen et al.   BIOCHEMISTRY

Brg1-dependent epigenetic control of vascular smooth muscle cell proliferation by hydrogen sulfide

(2013) Li Li et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Specific transcriptional enhancement of inducible nitric oxide synthase by targeted promoter demethylation

(2013) David J Gregory et al.   Epigenetics

Nitric Oxide Modifies Global Histone Methylation by Inhibiting Jumonji C Domain-containing Demethylases

(2013) Jason R. Hickok et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Crosstalk between hydrogen sulfide and nitric oxide in endothelial cells

(2013) Zaid Altaany et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Functional Deterioration of Endothelial Nitric Oxide Synthase after Focal Cerebral Ischemia

(2013) Yoshiki Yagita et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Physiological role of hydrogen sulfide and polysulfide in the central nervous system

(2013) Hideo Kimura   NEUROCHEMISTRY INTERNATIONAL

Aberrant Protein S-Nitrosylation in Neurodegenerative Diseases

(2013) Tomohiro Nakamura et al.   NEURON

Correction: Tertiary Origin and Pleistocene Diversification of Dragon Blood Tree (Dracaena cambodiana-Asparagaceae) Populations in the Asian Tropical Forests

(2013) Jian-Li Zhao et al.   PLoS One

The role of nitric oxide in pre-synaptic plasticity and homeostasis

(2013) Neil Hardingham et al.   Frontiers in Cellular Neuroscience

A tale of two gases: NO and H2S, foes or friends for life?

(2013) Gopi K. Kolluru et al.   Redox Biology

Cerebral ischemia-reperfusion induces GAPDH S-nitrosylation and nuclear translocation

(2012) Chong Li et al.   BIOCHEMISTRY-MOSCOW

Hydrogen sulfide inhibits the translational expression of hypoxia-inducible factor-1α

(2012) Bo Wu et al.   BRITISH JOURNAL OF PHARMACOLOGY

Expression patterns of histone deacetylases in experimental stroke and potential targets for neuroprotection

(2012) Yan-Ting Chen et al.   CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY

Histone Deacetylase-1 (HDAC1) Is a Molecular Switch between Neuronal Survival and Death

(2012) Farah H. Bardai et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A Novel Hydrogen Sulfide-releasingN-Methyl-d-Aspartate Receptor Antagonist Prevents Ischemic Neuronal Death

(2012) Eizo Marutani et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

S-nitrosylation of B23/nucleophosmin by GAPDH protects cells from the SIAH1–GAPDH death cascade

(2012) Sang Bae Lee et al.   JOURNAL OF CELL BIOLOGY

S-nitrosylated protein disulfide isomerase contributes to mutant SOD1 aggregates in amyotrophic lateral sclerosis

(2012) Xueping Chen et al.   JOURNAL OF NEUROCHEMISTRY

The inhibitory effect of S-nitrosoglutathione on blood-brain barrier disruption and peroxynitrite formation in a rat model of experimental stroke

(2012) Mushfiquddin Khan et al.   JOURNAL OF NEUROCHEMISTRY

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(2012) Yinzhong Zhang et al.   MOLECULAR MEDICINE

Genome-wide association study identifies a variant in HDAC9 associated with large vessel ischemic stroke

(2012) Céline Bellenguez et al.   NATURE GENETICS

Histone acetylation rescues contextual fear conditioning in nNOS KO mice and accelerates extinction of cued fear conditioning in wild type mice

(2012) Yossef Itzhak et al.   NEUROBIOLOGY OF LEARNING AND MEMORY

Hydrogen sulfide and nitric oxide are mutually dependent in the regulation of angiogenesis and endothelium-dependent vasorelaxation

(2012) C. Coletta et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Neuron-Specific Prolyl-4-Hydroxylase Domain 2 Knockout Reduces Brain Injury After Transient Cerebral Ischemia

(2012) Reiner Kunze et al.   STROKE

Hydrogen Sulfide Inhibits Hypoxia- But Not Anoxia-Induced Hypoxia-Inducible Factor 1 Activation in a von Hippel-Lindau- and Mitochondria-Dependent Manner

(2011) Shinichi Kai et al.   ANTIOXIDANTS & REDOX SIGNALING

Biochemical insight into physiological effects of H2S: reaction with peroxynitrite and formation of a new nitric oxide donor, sulfinyl nitrite

(2011) Milos R. Filipovic et al.   BIOCHEMICAL JOURNAL

Protein S-nitrosylation: Role for nitric oxide signaling in neuronal death

(2011) Neelam Shahani et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Regulation of mitochondrial processes by protein S-nitrosylation

(2011) Claude A. Piantadosi   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Hydroxylation of 5-Methylcytosine by TET1 Promotes Active DNA Demethylation in the Adult Brain

(2011) Junjie U. Guo et al.   CELL

S-Glutathionylation: A Redox-Sensitive Switch Participating in Nitroso-Redox Balance

(2011) Raul A. Dulce et al.   CIRCULATION RESEARCH

Dinitrosyliron complexes are the most abundant nitric oxide-derived cellular adduct: biological parameters of assembly and disappearance

(2011) Jason R. Hickok et al.   FREE RADICAL BIOLOGY AND MEDICINE

Regulation byS-Nitrosylation of Protein Post-translational Modification

(2011) Douglas T. Hess et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

eNOS activation and NO function: Structural motifs responsible for the posttranslational control of endothelial nitric oxide synthase activity

(2011) Ruslan Rafikov et al.   JOURNAL OF ENDOCRINOLOGY

Studies on the Reaction of Nitric Oxide with the Hypoxia-Inducible Factor Prolyl Hydroxylase Domain 2 (EGLN1)

(2011) Rasheduzzaman Chowdhury et al.   JOURNAL OF MOLECULAR BIOLOGY

S-Nitrosylation at the Interface of Autophagy and Disease

(2011) Saptarsi M. Haldar et al.   MOLECULAR CELL

Complex Inhibitory Effects of Nitric Oxide on Autophagy

(2011) Sovan Sarkar et al.   MOLECULAR CELL

S-Nitrosylation and S-Palmitoylation Reciprocally Regulate Synaptic Targeting of PSD-95

(2011) Gary P.H. Ho et al.   NEURON

Nitric oxide activates Nrf2 through S-nitrosylation of Keap1 in PC12 cells

(2011) Han-Cheon Um et al.   NITRIC OXIDE-BIOLOGY AND CHEMISTRY

On-off system for PI3-kinase-Akt signaling through S-nitrosylation of phosphatase with sequence homology to tensin (PTEN)

(2011) N. Numajiri et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Neurotrophin-mediated degradation of histone methyltransferase by S-nitrosylation cascade regulates neuronal differentiation

(2011) N. Sen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

H2S-Induced Sulfhydration of the Phosphatase PTP1B and Its Role in the Endoplasmic Reticulum Stress Response

(2011) N. Krishnan et al.   Science Signaling

Nitric Oxide Signaling and Nitrosative Stress in Neurons: Role for S-Nitrosylation

(2010) Neelam Shahani et al.   ANTIOXIDANTS & REDOX SIGNALING

Histone Deacetylase 3 Antagonizes Aspirin-Stimulated Endothelial Nitric Oxide Production by Reversing Aspirin-Induced Lysine Acetylation of Endothelial Nitric Oxide Synthase

(2010) Saet-Byel Jung et al.   CIRCULATION RESEARCH

Neuronal MeCP2 Is Expressed at Near Histone-Octamer Levels and Globally Alters the Chromatin State

(2010) Peter J. Skene et al.   MOLECULAR CELL

NO signaling and S-nitrosylation regulate PTEN inhibition in neurodegeneration

(2010) Young-Don Kwak et al.   Molecular Neurodegeneration

S-glutathionylation uncouples eNOS and regulates its cellular and vascular function

(2010) Chun-An Chen et al.   NATURE

GAPDH mediates nitrosylation of nuclear proteins

(2010) Michael D. Kornberg et al.   NATURE CELL BIOLOGY

Dynamic epigenetic regulation in neurons: enzymes, stimuli and signaling pathways

(2010) Antonella Riccio   NATURE NEUROSCIENCE

GAPDH regulates cellular heme insertion into inducible nitric oxide synthase

(2010) R. Chakravarti et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Endothelial Dysfunction, Vascular Disease and Stroke: The ARTICO Study

(2009) J. Roquer et al.   CEREBROVASCULAR DISEASES

Folic Acid, Neurodegenerative and Neuropsychiatric Disease

(2009) Golo Kronenberg et al.   CURRENT MOLECULAR MEDICINE

Hypoxic Repression of Endothelial Nitric-oxide Synthase Transcription Is Coupled with Eviction of Promoter Histones

(2009) Jason E. Fish et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

HDAC2 negatively regulates memory formation and synaptic plasticity

(2009) Ji-Song Guan et al.   NATURE

S-nitrosylation of PTEN Invovled in Ischemic Brain Injury in Rat Hippocampal CA1 Region

(2009) Dong-Sheng Pei et al.   NEUROCHEMICAL RESEARCH

GOSPEL: A Neuroprotective Protein that Binds to GAPDH upon S-Nitrosylation

(2009) Nilkantha Sen et al.   NEURON

Hydrogen sulfide is an endogenous stimulator of angiogenesis

(2009) A. Papapetropoulos et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Nuclear DNA Base 5-Hydroxymethylcytosine Is Present in Purkinje Neurons and the Brain

(2009) S. Kriaucionis et al.   SCIENCE

3-Mercaptopyruvate Sulfurtransferase Produces Hydrogen Sulfide and Bound Sulfane Sulfur in the Brain

(2008) Norihiro Shibuya et al.   ANTIOXIDANTS & REDOX SIGNALING

Epigenetic Regulation of Vascular Endothelial Gene Expression

(2008) Charles C. Matouk et al.   CIRCULATION RESEARCH

CysteineS-Nitrosylation Protects Protein-tyrosine Phosphatase 1B against Oxidation-induced Permanent Inactivation

(2008) Yi-Yun Chen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Hypoxia induces a novel signature of chromatin modifications and global repression of transcription

(2008) Amber Buescher Johnson et al.   MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS

S-nitrosylation of histone deacetylase 2 induces chromatin remodelling in neurons

(2008) Alexi Nott et al.   NATURE

Nitric oxide-induced nuclear GAPDH activates p300/CBP and mediates apoptosis

(2008) Nilkantha Sen et al.   NATURE CELL BIOLOGY

Therapeutic application of histone deacetylase inhibitors for central nervous system disorders

(2008) Aleksey G. Kazantsev et al.   NATURE REVIEWS DRUG DISCOVERY

Cell death and endoplasmic reticulum stress: disease relevance and therapeutic opportunities

(2008) Inki Kim et al.   NATURE REVIEWS DRUG DISCOVERY

H2S as a Physiologic Vasorelaxant: Hypertension in Mice with Deletion of Cystathionine  -Lyase

(2008) G. Yang et al.   SCIENCE