Heme Oxygenase Inhibition Sensitizes Neuroblastoma Cells to Carfilzomib

Potholing of the hydrophobic heme oxygenase-1 western region for the search of potent and selective imidazole-based inhibitors

(2018) Loredana Salerno et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Heme oxygenase-1: A new druggable target in the management of chronic and acute myeloid leukemia

(2017) Loredana Salerno et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Effect of Lipoic Acid on the Biochemical Mechanisms of Resistance to Bortezomib in SH-SY5Y Neuroblastoma Cells

(2017) Daniele Tibullo et al.   MOLECULAR NEUROBIOLOGY

Phase I study of bortezomib in combination with irinotecan in patients with relapsed/refractory high-risk neuroblastoma

(2017) Rajen Mody et al.   PEDIATRIC BLOOD & CANCER

Heme oxygenase-1 nuclear translocation regulates bortezomib-induced cytotoxicity and mediates genomic instability in myeloma cells

(2016) Daniele Tibullo et al.   Oncotarget

Second-generation proteasome inhibitor carfilzomib sensitizes neuroblastoma cells to doxorubicin-induced apoptosis

(2016) Shan Guan et al.   Oncotarget

The non-canonical functions of the heme oxygenases

(2016) Luca Vanella et al.   Oncotarget

A Focus on Heme Oxygenase-1 (HO-1) Inhibitors

(2016) V. Pittalà et al.   CURRENT MEDICINAL CHEMISTRY

Role of Nrf2, HO-1 and GSH in Neuroblastoma Cell Resistance to Bortezomib

(2016) A. L. Furfaro et al.   PLoS One

Novel proteasome inhibitor ixazomib sensitizes neuroblastoma cells to doxorubicin treatment

(2016) Haoyu Li et al.   Scientific Reports

Combined inhibition of Hsp90 and heme oxygenase-1 induces apoptosis and endoplasmic reticulum stress in melanoma

(2015) Ignazio Barbagallo et al.   ACTA HISTOCHEMICA

Novel imidazole derivatives as heme oxygenase-1 (HO-1) and heme oxygenase-2 (HO-2) inhibitors and their cytotoxic activity in human-derived cancer cell lines

(2015) Loredana Salerno et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

HO-1 up-regulation: A key point in high-risk neuroblastoma resistance to bortezomib

(2014) Anna Lisa Furfaro et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

The Role of the Heme Oxygenase System in the Metabolic Syndrome

(2014) Ignazio Barbagallo et al.   CURRENT PHARMACEUTICAL DESIGN

The ubiquitin–proteasome system: opportunities for therapeutic intervention in solid tumors

(2014) Daniel E Johnson   ENDOCRINE-RELATED CANCER

Evaluation of novel aryloxyalkyl derivatives of imidazole and 1,2,4-triazole as heme oxygenase-1 (HO-1) inhibitors and their antitumor properties

(2013) Loredana Salerno et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Nuclear Translocation of Heme Oxygenase-1 Confers Resistance to Imatinib in Chronic Myeloid Leukemia Cells

(2013) Daniele Tibullo et al.   CURRENT PHARMACEUTICAL DESIGN

Potential Therapeutic Effects of Natural Heme Oxygenase-1 Inducers in Cardiovascular Diseases

(2012) Ignazio Barbagallo et al.   ANTIOXIDANTS & REDOX SIGNALING

Evaluation of Imidazole-Based Compounds as Heme Oxygenase-1 Inhibitors

(2012) Valeria Sorrenti et al.   Chemical Biology & Drug Design

Synthesis and molecular modeling of 1H-pyrrolopyrimidine-2,4-dione derivatives as ligands for the α1-adrenoceptors

(2011) Valeria Pittalà et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Resistance of neuroblastoma GI-ME-N cell line to glutathione depletion involves Nrf2 and heme oxygenase-1

(2011) Anna Lisa Furfaro et al.   FREE RADICAL BIOLOGY AND MEDICINE

Effects of second-generation tyrosine kinase inhibitors towards osteogenic differentiation of human mesenchymal cells of healthy donors

(2011) Daniele Tibullo et al.   HEMATOLOGICAL ONCOLOGY

High Levels of Nrf2 Determine Chemoresistance in Type II Endometrial Cancer

(2010) T. Jiang et al.   CANCER RESEARCH

Loss of Keap1 Function Activates Nrf2 and Provides Advantages for Lung Cancer Cell Growth

(2008) T. Ohta et al.   CANCER RESEARCH

Genetic Alteration of Keap1 Confers Constitutive Nrf2 Activation and Resistance to Chemotherapy in Gallbladder Cancer

(2008) Tatsuhiro Shibata et al.   GASTROENTEROLOGY