Effects of second-generation tyrosine kinase inhibitors towards osteogenic differentiation of human mesenchymal cells of healthy donors

The Src inhibitor dasatinib accelerates the differentiation of human bone marrow-derived mesenchymal stromal cells into osteoblasts

(2010) Hichame Id Boufker et al.   BMC CANCER

Phase 1 pharmacokinetic and drug-interaction study of dasatinib in patients with advanced solid tumors

(2010) Faye M. Johnson et al.   CANCER

The tyrosine kinase inhibitor dasatinib dysregulates bone remodeling through inhibition of osteoclasts in vivo

(2010) Kate Vandyke et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Second-generation TKI dasatinib inhibits proliferation of mesenchymal stem cells and osteoblast differentiation in vitro

(2010) S Jönsson et al.   LEUKEMIA

Mesenchymal Stromal Cells

(2009) Maria Ester Bernardo et al.   Annals of the New York Academy of Sciences

Acute dasatinib exposure commits Bcr-Abl-dependent cells to apoptosis

(2009) J. L. Snead et al.   BLOOD

Clinical Pharmacokinetics of the BCR–ABL Tyrosine Kinase Inhibitor Nilotinib

(2009) C Tanaka et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

Effects of imatinib mesylate in osteoblastogenesis

(2009) Daniele Tibullo et al.   EXPERIMENTAL HEMATOLOGY

Growth deceleration in a girl treated with imatinib

(2009) Tomiko Kimoto et al.   INTERNATIONAL JOURNAL OF HEMATOLOGY

Decreased Bone Turnover Despite Persistent Secondary Hyperparathyroidism during Prolonged Treatment with Imatinib

(2009) Susannah O'Sullivan et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Peroxisome Proliferator-Activated Receptor-γ Agonists Promote Differentiation and Antioxidant Defenses of Oligodendrocyte Progenitor Cells

(2009) Antonietta Bernardo et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

Effects of Dasatinib on Src Kinase Activity and Downstream Intracellular Signaling in Primitive Chronic Myelogenous Leukemia Hematopoietic Cells

(2008) H. Konig et al.   CANCER RESEARCH

Increased cortical bone mineralization in imatinib treated patients with chronic myelogenous leukemia

(2008) S. Jonsson et al.   HAEMATOLOGICA

Structural Coupling of Smad and Runx2 for Execution of the BMP2 Osteogenic Signal

(2008) Amjad Javed et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

PDGF Receptor β Is a Potent Regulator of Mesenchymal Stromal Cell Function

(2008) Ayano Tokunaga et al.   JOURNAL OF BONE AND MINERAL RESEARCH

A cytoprotective role for the heme oxygenase‐1/CO pathway during neural differentiation of human mesenchymal stem cells

(2008) Ignazio Barbagallo et al.   JOURNAL OF NEUROSCIENCE RESEARCH

Therapeutic concentrations of dasatinib inhibit in vitro osteoclastogenesis

(2008) K Vandyke et al.   LEUKEMIA

Imatinib mesylate (IM)-induced growth inhibition is associated with production of spliced osteocalcin—mRNA in cell lines

(2007) Peter Wihlidal et al.   LEUKEMIA RESEARCH