Folic Acid Exerts Post-Ischemic Neuroprotection In Vitro Through HIF-1α Stabilization

New horizons in hypoxia signaling pathways

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Targeting Protein-Protein Interactions in the HIF System

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Folic acid deficiency increases brain cell injury via autophagy enhancement after focal cerebral ischemia

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Efficacy of Folic Acid Therapy in Primary Prevention of Stroke Among Adults With Hypertension in China

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Nrf2 in ischemic neurons promotes retinal vascular regeneration through regulation of semaphorin 6A

(2015) Yanhong Wei et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Folate Deficiency Could Restrain Decidual Angiogenesis in Pregnant Mice

(2015) Yanli Li et al.   Nutrients

Drug Repurposing: A Systematic Approach to Evaluate Candidate Oral Neuroprotective Interventions for Secondary Progressive Multiple Sclerosis

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Ensemble pharmacophore meets ensemble docking: a novel screening strategy for the identification of RIPK1 inhibitors

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Inhibition of HIF prolyl-4-hydroxylases by FG-4497 Reduces Brain Tissue Injury and Edema Formation during Ischemic Stroke

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Vascular remodeling after ischemic stroke: Mechanisms and therapeutic potentials

(2013) Jialing Liu et al.   PROGRESS IN NEUROBIOLOGY

Nrf2 activation supports cell survival during hypoxia and hypoxia/reoxygenation in cardiomyoblasts; the roles of reactive oxygen and nitrogen species

(2013) Rajitha T Kolamunne et al.   Redox Biology

Folic acid inhibits endothelial cell proliferation through activating the cSrc/ERK 2/NF-κB/p53 pathway mediated by folic acid receptor

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Biomolecular Simulation: A Computational Microscope for Molecular Biology

(2012) Ron O. Dror et al.   Annual Review of Biophysics

Hypoxia-Inducible Factors in Physiology and Medicine

(2012) Gregg L. Semenza   CELL

Dissecting Fragment-Based Lead Discovery at the von Hippel-Lindau Protein:Hypoxia Inducible Factor 1α Protein-Protein Interface

(2012) Inge Van Molle et al.   CHEMISTRY & BIOLOGY

Efficacy of folic acid supplementation in stroke prevention: new insight from a meta-analysis

(2012) Y. Huo et al.   INTERNATIONAL JOURNAL OF CLINICAL PRACTICE

Hypoxia-Inducible Factor Prolyl Hydroxylase Inhibition: Robust New Target or Another Big Bust for Stroke Therapeutics?

(2012) Saravanan S Karuppagounder et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Folic acid enhances Notch signaling, hippocampal neurogenesis, and cognitive function in a rat model of cerebral ischemia

(2012) Xumei Zhang et al.   NUTRITIONAL NEUROSCIENCE

The effects of homocysteine and folic acid on angiogenesis and VEGF expression during chicken vascular development

(2011) Annelien M. Oosterbaan et al.   MICROVASCULAR RESEARCH

Inhibition of prolyl hydroxylases by dimethyloxaloylglycine after stroke reduces ischemic brain injury and requires hypoxia inducible factor-1α

(2011) Molly E. Ogle et al.   NEUROBIOLOGY OF DISEASE

HIF-1α signaling is augmented during intermittent hypoxia by induction of the Nrf2 pathway in NOX1-expressing adenocarcinoma A549 cells

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Neuroprotection by Dimethyloxalylglycine following Permanent and Transient Focal Cerebral Ischemia in Rats

(2010) Simon Nagel et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Hypoxia Inducible Factor 1 as a Therapeutic Target in Ischemic Stroke

(2009) Honglian Shi   CURRENT MEDICINAL CHEMISTRY

AutoDock4 and AutoDockTools4: Automated docking with selective receptor flexibility

(2009) Garrett M. Morris et al.   JOURNAL OF COMPUTATIONAL CHEMISTRY

Specific inhibition of hypoxia inducible factor 1 exaggerates cell injury induced byin vitroischemia through deteriorating cellular redox environment

(2009) Shuhong Guo et al.   JOURNAL OF NEUROCHEMISTRY

Target identification using drug affinity responsive target stability (DARTS)

(2009) B. Lomenick et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Structural Basis for Binding of Hypoxia-Inducible Factor to the Oxygen-Sensing Prolyl Hydroxylases

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