Nrf2 in ischemic neurons promotes retinal vascular regeneration through regulation of semaphorin 6A

Endothelial PGC-1α Mediates Vascular Dysfunction in Diabetes

(2014) Naoki Sawada et al.   Cell Metabolism

Neuropilin-1 mediates myeloid cell chemoattraction and influences retinal neuroimmune crosstalk

(2014) Agnieszka Dejda et al.   JOURNAL OF CLINICAL INVESTIGATION

Subcellular localization of coagulation factor II receptor-like 1 in neurons governs angiogenesis

(2014) Jean-Sébastien Joyal et al.   NATURE MEDICINE

Neuronal sirtuin1 mediates retinal vascular regeneration in oxygen-induced ischemic retinopathy

(2013) Jing Chen et al.   ANGIOGENESIS

Neuronal ER Stress Impedes Myeloid-Cell-Induced Vascular Regeneration through IRE1α Degradation of Netrin-1

(2013) François Binet et al.   Cell Metabolism

NRF2 plays a protective role in diabetic retinopathy in mice

(2013) Zhenhua Xu et al.   DIABETOLOGIA

Sulforaphane preconditioning of the Nrf2/HO-1 defense pathway protects the cerebral vasculature against blood–brain barrier disruption and neurological deficits in stroke

(2013) Alessio Alfieri et al.   FREE RADICAL BIOLOGY AND MEDICINE

Knockdown of Nrf2 suppresses glioblastoma angiogenesis by inhibiting hypoxia-induced activation of HIF-1α

(2013) Xiangjun Ji et al.   INTERNATIONAL JOURNAL OF CANCER

Functional genomic screening identifies dual leucine zipper kinase as a key mediator of retinal ganglion cell death

(2013) D. S. Welsbie et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Endothelin-2 signaling in the neural retina promotes the endothelial tip cell state and inhibits angiogenesis

(2013) A. Rattner et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Nrf2 acts cell-autonomously in endothelium to regulate tip cell formation and vascular branching

(2013) Y. Wei et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

On and Off Retinal Circuit Assembly by Divergent Molecular Mechanisms

(2013) L. O. Sun et al.   SCIENCE

MEF2C Ablation in Endothelial Cells Reduces Retinal Vessel Loss and Suppresses Pathologic Retinal Neovascularization in Oxygen-Induced Retinopathy

(2012) Zhenhua Xu et al.   AMERICAN JOURNAL OF PATHOLOGY

Semaphorin 6A regulates angiogenesis by modulating VEGF signaling

(2012) M. Segarra et al.   BLOOD

Eyeing central neurons in vascular growth and reparative angiogenesis

(2012) P. Sapieha   BLOOD

Disruption of Nrf2 Signaling Impairs Angiogenic Capacity of Endothelial Cells: Implications for Microvascular Aging

(2012) M. N. Valcarcel-Ares et al.   JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES

Injury and repair in the neurovascular unit

(2012) Changhong Xing et al.   NEUROLOGICAL RESEARCH

Identification of novel NRF2-regulated genes by ChIP-Seq: influence on retinoid X receptor alpha

(2012) B. N. Chorley et al.   NUCLEIC ACIDS RESEARCH

Endothelial Semaphorin 7A promotes neutrophil migration during hypoxia

(2012) J. C. Morote-Garcia et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Emerging roles of Nrf2 and phase II antioxidant enzymes in neuroprotection

(2012) Meijuan Zhang et al.   PROGRESS IN NEUROBIOLOGY

Enhancing Nrf2 Pathway by Disruption of Keap1 in Myeloid Leukocytes Protects against Sepsis

(2011) Xiaoni Kong et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Ischemic neurons prevent vascular regeneration of neural tissue by secreting semaphorin 3A

(2011) J.-S. Joyal et al.   BLOOD

MicroRNA-27a/b controls endothelial cell repulsion and angiogenesis by targeting semaphorin 6A

(2011) C. Urbich et al.   BLOOD

NRF2 Blockade Suppresses Colon Tumor Angiogenesis by Inhibiting Hypoxia-Induced Activation of HIF-1 

(2011) T.-H. Kim et al.   CANCER RESEARCH

Inhibition of pathological retinal angiogenesis by the integrin αvβ3 antagonist tetraiodothyroacetic acid (tetrac)

(2011) Takeshi Yoshida et al.   EXPERIMENTAL EYE RESEARCH

The deletion of Math5 disrupts retinal blood vessel and glial development in mice

(2011) Malia M. Edwards et al.   EXPERIMENTAL EYE RESEARCH

Nrf2 has a protective role against neuronal and capillary degeneration in retinal ischemia–reperfusion injury

(2011) Yanhong Wei et al.   FREE RADICAL BIOLOGY AND MEDICINE

Semaphorin 3E-Plexin-D1 signaling regulates VEGF function in developmental angiogenesis via a feedback mechanism

(2011) J. Kim et al.   GENES & DEVELOPMENT

Sema3E-PlexinD1 signaling selectively suppresses disoriented angiogenesis in ischemic retinopathy in mice

(2011) Yoko Fukushima et al.   JOURNAL OF CLINICAL INVESTIGATION

Role of ROS in ischemia-induced lung angiogenesis

(2010) Julie Nijmeh et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Ablation of the Transcription Factor Nrf2 Promotes Ischemia-Induced Neovascularization by Enhancing the Inflammatory Response

(2010) Sahoko Ichihara et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Cis interaction between Semaphorin6A and Plexin-A4 modulates the repulsive response to Sema6A

(2010) Liat Haklai-Topper et al.   EMBO JOURNAL

The Science of Stroke: Mechanisms in Search of Treatments

(2010) Michael A. Moskowitz et al.   NEURON

Global mapping of binding sites for Nrf2 identifies novel targets in cell survival response through ChIP-Seq profiling and network analysis

(2010) Deepti Malhotra et al.   NUCLEIC ACIDS RESEARCH

Guidance of Vascular Development

(2009) Bruno Larrivée et al.   CIRCULATION RESEARCH

Inhibition of Semaphorin As a Novel Strategy for Therapeutic Angiogenesis

(2009) Junji Moriya et al.   CIRCULATION RESEARCH

Hypoxia-inducible Factor-1-mediated Regulation of Semaphorin 4D Affects Tumor Growth and Vascularity

(2009) Qiangming Sun et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Histone H2AX is integral to hypoxia-driven neovascularization

(2009) Matina Economopoulou et al.   NATURE MEDICINE

Quantification of oxygen-induced retinopathy in the mouse: a model of vessel loss, vessel regrowth and pathological angiogenesis

(2009) Kip M Connor et al.   Nature Protocols

The Nrf2/ARE Pathway as a Potential Therapeutic Target in Neurodegenerative Disease

(2008) Marcus J. Calkins et al.   ANTIOXIDANTS & REDOX SIGNALING

The succinate receptor GPR91 in neurons has a major role in retinal angiogenesis

(2008) Przemyslaw Sapieha et al.   NATURE MEDICINE

Regulation of multiple angiogenic pathways by Dll4 and Notch in human umbilical vein endothelial cells

(2007) Laura S. Harrington et al.   MICROVASCULAR RESEARCH