Uncoupling of glycolysis from glucose oxidation accompanies the development of heart failure with preserved ejection fraction

Pyruvate dehydrogenase as a therapeutic target for obesity cardiomyopathy

(2016) Andrew JM Lewis et al.   EXPERT OPINION ON THERAPEUTIC TARGETS

Preservation of myocardial fatty acid oxidation prevents diastolic dysfunction in mice subjected to angiotensin II infusion

(2016) Yong Seon Choi et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

In vivo assessment of cardiac metabolism and function in the abdominal aortic banding model of compensated cardiac hypertrophy

(2015) Anne-Marie L. Seymour et al.   CARDIOVASCULAR RESEARCH

Energy Metabolic Reprogramming in the Hypertrophied and Early Stage Failing Heart

(2014) Ling Lai et al.   Circulation-Heart Failure

Murine Models of Diastolic Dysfunction and Heart Failure With Preserved Ejection Fraction

(2014) S. Horgan et al.   JOURNAL OF CARDIAC FAILURE

Metabolic programming and PDHK1 control CD4+ T cell subsets and inflammation

(2014) Valerie A. Gerriets et al.   JOURNAL OF CLINICAL INVESTIGATION

GLUT1 deficiency in cardiomyocytes does not accelerate the transition from compensated hypertrophy to heart failure

(2014) Renata O. Pereira et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

ANG II causes insulin resistance and induces cardiac metabolic switch and inefficiency: a critical role of PDK4

(2013) Jun Mori et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Failing mouse hearts utilize energy inefficiently and benefit from improved coupling of glycolysis and glucose oxidation

(2013) Waleed G.T. Masoud et al.   CARDIOVASCULAR RESEARCH

Cardiac Insulin-Resistance and Decreased Mitochondrial Energy Production Precede the Development of Systolic Heart Failure After Pressure-Overload Hypertrophy

(2013) Liyan Zhang et al.   Circulation-Heart Failure

Stimulation of glucose oxidation protects against acute myocardial infarction and reperfusion injury

(2012) John R. Ussher et al.   CARDIOVASCULAR RESEARCH

Pressure-overload-induced heart failure induces a selective reduction in glucose oxidation at physiological afterload

(2012) Pavel Zhabyeyev et al.   CARDIOVASCULAR RESEARCH

Hyperpolarized13C magnetic resonance reveals early- and late-onset changes toin vivopyruvate metabolism in the failing heart

(2012) Marie A. Schroeder et al.   EUROPEAN JOURNAL OF HEART FAILURE

FOXO1-mediated upregulation of pyruvate dehydrogenase kinase-4 (PDK4) decreases glucose oxidation and impairs right ventricular function in pulmonary hypertension: therapeutic benefits of dichloroacetate

(2012) Lin Piao et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

Angiotensin-Converting Enzyme 2 Suppresses Pathological Hypertrophy, Myocardial Fibrosis, and Cardiac Dysfunction

(2010) JiuChang Zhong et al.   CIRCULATION

Analysis of Metabolic Remodeling in Compensated Left Ventricular Hypertrophy and Heart Failure

(2010) Takao Kato et al.   Circulation-Heart Failure

Myocardial Fatty Acid Metabolism in Health and Disease

(2010) Gary D. Lopaschuk et al.   PHYSIOLOGICAL REVIEWS

Insulin-Stimulated Cardiac Glucose Oxidation Is Increased in High-Fat Diet-Induced Obese Mice Lacking Malonyl CoA Decarboxylase

(2009) J. R. Ussher et al.   DIABETES

The inhibition of pyruvate dehydrogenase kinase improves impaired cardiac function and electrical remodeling in two models of right ventricular hypertrophy: resuscitating the hibernating right ventricle

(2009) Lin Piao et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

Understanding the Warburg Effect: The Metabolic Requirements of Cell Proliferation

(2009) M. G. Vander Heiden et al.   SCIENCE

Activation of lipogenic pathway correlates with cell proliferation and poor prognosis in hepatocellular carcinoma

(2008) Taro Yamashita et al.   JOURNAL OF HEPATOLOGY