Exosomal miR-423-5p targets SUFU to promote cancer growth and metastasis and serves as a novel marker for gastric cancer

Tumor-derived exosomal miR-1247-3p induces cancer-associated fibroblast activation to foster lung metastasis of liver cancer

(2018) Tian Fang et al.   Nature Communications

Gastric cancer-derived exosomes promote peritoneal metastasis by destroying the mesothelial barrier

(2017) Guang Deng et al.   FEBS LETTERS

Exosome-delivered EGFR regulates liver microenvironment to promote gastric cancer liver metastasis

(2017) Haiyang Zhang et al.   Nature Communications

miR-423-5p contributes to a malignant phenotype and temozolomide chemoresistance in glioblastomas

(2016) Shouwei Li et al.   NEURO-ONCOLOGY

Exosomes derived from gastric cancer cells activate NF-κB pathway in macrophages to promote cancer progression

(2016) Lijun Wu et al.   TUMOR BIOLOGY

YKT6 expression, exosome release, and survival in non-small cell lung cancer

(2016) Marc Ruiz-Martinez et al.   Oncotarget

Circular RNA is enriched and stable in exosomes: a promising biomarker for cancer diagnosis

(2015) Yan Li et al.   CELL RESEARCH

Morphological and molecular features of oral fluid-derived exosomes: oral cancer patients versus healthy individuals

(2015) Ayelet Zlotogorski-Hurvitz et al.   JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY

Exosomes in cancer: small particle, big player

(2015) Xu Zhang et al.   Journal of Hematology & Oncology

MicroRNA molecular profiling from matched tumor and bio-fluids in bladder cancer

(2015) David A. Armstrong et al.   Molecular Cancer

Glypican-1 identifies cancer exosomes and detects early pancreatic cancer

(2015) Sonia A. Melo et al.   NATURE

High serum levels of extracellular vesicles expressing malignancy-related markers are released in patients with various types of hematological neoplastic disorders

(2015) Antonella Caivano et al.   TUMOR BIOLOGY

Exosomal levels of miRNA-21 from cerebrospinal fluids associated with poor prognosis and tumor recurrence of glioma patients

(2015) Rui Shi et al.   Oncotarget

microRNA-214 promotes epithelial-mesenchymal transition and metastasis in lung adenocarcinoma by targeting the suppressor-of-fused protein (Sufu)

(2015) Haixia Long et al.   Oncotarget

MicroRNA-423-5p Promotes Autophagy in Cancer Cells and Is Increased in Serum From Hepatocarcinoma Patients Treated With Sorafenib

(2015) Paola Stiuso et al.   Molecular Therapy-Nucleic Acids

Urothelial cells undergo epithelial-to-mesenchymal transition after exposure to muscle invasive bladder cancer exosomes

(2015) C A Franzen et al.   Oncogenesis

Exosomal miRNAs from Peritoneum Lavage Fluid as Potential Prognostic Biomarkers of Peritoneal Metastasis in Gastric Cancer

(2015) Motohiko Tokuhisa et al.   PLoS One

Suppressor of fused (Sufu) represses Gli1 transcription and nuclear accumulation, inhibits glioma cell proliferation, invasion and vasculogenic mimicry, improving glioma chemo-sensitivity and prognosis

(2015) Xing Liu et al.   Oncotarget

Exosomal miR-221/222 enhances tamoxifen resistance in recipient ER-positive breast cancer cells

(2014) Yifang Wei et al.   BREAST CANCER RESEARCH AND TREATMENT

Deregulated microRNAs in gastric cancer tissue-derived mesenchymal stem cells: novel biomarkers and a mechanism for gastric cancer

(2014) M Wang et al.   BRITISH JOURNAL OF CANCER

Cancer Exosomes Perform Cell-Independent MicroRNA Biogenesis and Promote Tumorigenesis

(2014) Sonia A. Melo et al.   CANCER CELL

miRNA423-5p regulates cell proliferation and invasion by targeting trefoil factor 1 in gastric cancer cells

(2014) Jingjing Liu et al.   CANCER LETTERS

miRNA in Plasma Exosome is Stable under Different Storage Conditions

(2014) Qinyu Ge et al.   MOLECULES

Plasma long noncoding RNA protected by exosomes as a potential stable biomarker for gastric cancer

(2014) Qier Li et al.   TUMOR BIOLOGY

A systematic review of microRNA expression profiling studies in human gastric cancer

(2014) Sirjana Shrestha et al.   Cancer Medicine

Exosomes in cancer development, metastasis, and drug resistance: a comprehensive review

(2013) Asfar S. Azmi et al.   CANCER AND METASTASIS REVIEWS

Tumor-derived exosomes are enriched in ΔNp73, which promotes oncogenic potential in acceptor cells and correlates with patient survival

(2013) Beatriz Soldevilla et al.   HUMAN MOLECULAR GENETICS

Heparanase Regulates Secretion, Composition, and Function of Tumor Cell-derived Exosomes

(2013) Camilla A. Thompson et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Analysis of serum exosomal microRNAs and clinicopathologic features of patients with pancreatic adenocarcinoma

(2013) Risheng Que et al.   World Journal of Surgical Oncology

Suppression of growth and migration by blocking the hedgehog signaling pathway in gastric cancer cells

(2013) Runwei Yan et al.   CELLULAR ONCOLOGY

Intricacies of hedgehog signaling pathways: A perspective in tumorigenesis

(2012) Swayamsiddha Kar et al.   EXPERIMENTAL CELL RESEARCH

The Majority of MicroRNAs Detectable in Serum and Saliva Is Concentrated in Exosomes

(2012) Alessia Gallo et al.   PLoS One

Gastric Cancer Exosomes Trigger Differentiation of Umbilical Cord Derived Mesenchymal Stem Cells to Carcinoma-Associated Fibroblasts through TGF-β/Smad Pathway

(2012) Jianmei Gu et al.   PLoS One

Twist1-Induced Invadopodia Formation Promotes Tumor Metastasis

(2011) Mark A. Eckert et al.   CANCER CELL

Analysis of exosome release and its prognostic value in human colorectal cancer

(2011) J. Silva et al.   GENES CHROMOSOMES & CANCER

A five-microRNA signature identified from genome-wide serum microRNA expression profiling serves as a fingerprint for gastric cancer diagnosis

(2010) Rui Liu et al.   EUROPEAN JOURNAL OF CANCER

Circulating tumour-derived microvesicles in plasma of gastric cancer patients

(2009) Jaroslaw Baran et al.   CANCER IMMUNOLOGY IMMUNOTHERAPY

Microenvironmental pH Is a Key Factor for Exosome Traffic in Tumor Cells

(2009) Isabella Parolini et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Rab27a and Rab27b control different steps of the exosome secretion pathway

(2009) Matias Ostrowski et al.   NATURE CELL BIOLOGY