Nickel exposure induces persistent mesenchymal phenotype in human lung epithelial cells through epigenetic activation of ZEB1

Identification of a unique gene expression signature in mercury and 2,3,7,8-tetrachlorodibenzo-p-dioxin co-exposed cells

(2017) Lakshmanan Jagannathan et al.   Toxicology Research

ZEB1 drives epithelial-to-mesenchymal transition in lung cancer

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ZEB1: At the crossroads of epithelial-mesenchymal transition, metastasis and therapy resistance

(2015) Peijing Zhang et al.   CELL CYCLE

Nuclear Factor κB1/RelA Mediates Inflammation in Human Lung Epithelial Cells at Atmospheric Oxygen Levels

(2015) Lakshmanan Jagannathan et al.   JOURNAL OF CELLULAR PHYSIOLOGY

ClustVis: a web tool for visualizing clustering of multivariate data using Principal Component Analysis and heatmap

(2015) Tauno Metsalu et al.   NUCLEIC ACIDS RESEARCH

Persistence of Smoking-Induced Dysregulation of MiRNA Expression in the Small Airway Epithelium Despite Smoking Cessation

(2015) Guoqing Wang et al.   PLoS One

Uncertain Inheritance: Transgenerational Effects of Environmental Exposures

(2014) Charles W. Schmidt   ENVIRONMENTAL HEALTH PERSPECTIVES

Molecular mechanisms of epithelial–mesenchymal transition

(2014) Samy Lamouille et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Epigenetic dysregulation by nickel through repressive chromatin domain disruption

(2014) Cynthia C. Jose et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Prognostic significance of Zinc finger E-box binding homeobox 1 (ZEB1) expression in cancer cells and cancer-associated fibroblasts in pancreatic head cancer

(2014) Peter Bronsert et al.   SURGERY

δEF1 associates with DNMT1 and maintains DNA methylation of the E-cadherin promoter in breast cancer cells

(2014) Akihiko Fukagawa et al.   Cancer Medicine

Causal analysis approaches in Ingenuity Pathway Analysis

(2013) Andreas Krämer et al.   BIOINFORMATICS

Vimentin, zeb1 and Sip1 are up-regulated in triple-negative and basal-like breast cancers: association with an aggressive tumour phenotype

(2013) Peeter Karihtala et al.   BREAST CANCER RESEARCH AND TREATMENT

Poised Chromatin at the ZEB1 Promoter Enables Breast Cancer Cell Plasticity and Enhances Tumorigenicity

(2013) Christine L. Chaffer et al.   CELL

A double take on bivalent promoters

(2013) P. Voigt et al.   GENES & DEVELOPMENT

E-cadherin-integrin crosstalk in cancer invasion and metastasis

(2013) M. Canel et al.   JOURNAL OF CELL SCIENCE

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MicroRNA-based regulation of epithelial-hybrid-mesenchymal fate determination

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Epithelial–mesenchymal transition in the pathophysiology of airway remodelling in asthma

(2012) Tillie-Louise Hackett   Current Opinion in Allergy and Clinical Immunology

Nickel-induced Epithelial-Mesenchymal Transition by Reactive Oxygen Species Generation and E-cadherin Promoter Hypermethylation

(2012) Chih-Hsien Wu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Transgenerational Actions of Environmental Compounds on Reproductive Disease and Identification of Epigenetic Biomarkers of Ancestral Exposures

(2012) Mohan Manikkam et al.   PLoS One

EMT and Stem Cell-Like Properties Associated with miR-205 and miR-200 Epigenetic Silencing Are Early Manifestations during Carcinogen-Induced Transformation of Human Lung Epithelial Cells

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Hallmarks of Cancer: The Next Generation

(2011) Douglas Hanahan et al.   CELL

Functional Cooperation between Snail1 and Twist in the Regulation ofZEB1Expression during Epithelial to Mesenchymal Transition

(2011) Natàlia Dave et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Exploring the molecular mechanisms of nickel-induced genotoxicity and carcinogenicity: a literature review

(2011) Keyuna S. Cameron et al.   REVIEWS ON ENVIRONMENTAL HEALTH

Snail Family Regulation and Epithelial Mesenchymal Transitions in Breast Cancer Progression

(2010) Antonio Garcia de Herreros et al.   JOURNAL OF MAMMARY GLAND BIOLOGY AND NEOPLASIA

ZEB1 represses E-cadherin and induces an EMT by recruiting the SWI/SNF chromatin-remodeling protein BRG1

(2010) E Sánchez-Tilló et al.   ONCOGENE

Complete reversal of epithelial to mesenchymal transition requires inhibition of both ZEB expression and the Rho pathway

(2009) Shreyas Das et al.   BMC CELL BIOLOGY

Epithelial-Mesenchymal Transitions in Development and Disease

(2009) Jean Paul Thiery et al.   CELL

The basics of epithelial-mesenchymal transition

(2009) Raghu Kalluri et al.   JOURNAL OF CLINICAL INVESTIGATION

Carcinogenic metal compounds: recent insight into molecular and cellular mechanisms

(2008) Detmar Beyersmann et al.   ARCHIVES OF TOXICOLOGY

A Double-Negative Feedback Loop between ZEB1-SIP1 and the microRNA-200 Family Regulates Epithelial-Mesenchymal Transition

(2008) C. P. Bracken et al.   CANCER RESEARCH

The miR-200 family and miR-205 regulate epithelial to mesenchymal transition by targeting ZEB1 and SIP1

(2008) Philip A. Gregory et al.   NATURE CELL BIOLOGY

Genetic and Epigenetic Mechanisms in Metal Carcinogenesis and Cocarcinogenesis: Nickel, Arsenic, and Chromium

(2007) Konstantin Salnikow et al.   CHEMICAL RESEARCH IN TOXICOLOGY